Anticlastogenic effects of black tea (World blend) and its two active polyphenols theaflavins and thearubigins in vivo in Swiss albino mice

Life Sciences

Volumn 69, Issue 23, 2001, Pages 2735-2744

  Gupta, S ^a   Chaudhuri, T ^a   Ganguly, D K ^a   Giri, A K ^a  

^a INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

Author keywords

Anticlastogenic; Black tea (World blend); In vivo; Mice; Theaflavins; Thearubigins

Indexed keywords

CARCINOGEN; CLASTOGEN; CYCLOPHOSPHAMIDE; DIMETHYLBENZ[A]ANTHRACENE; POLYPHENOL DERIVATIVE; THEAFLAVIN; THEARUBIGIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; CHROMOSOME ABERRATION; CONTROLLED STUDY; MALE; MOUSE; NONHUMAN; SISTER CHROMATID EXCHANGE; TEA;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ANIMALS; ANTIMUTAGENIC AGENTS; BIFLAVONOIDS; CATECHIN; CHROMOSOME ABERRATIONS; CYCLOPHOSPHAMIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; MICE; MUTAGENS; PHENOLS; SISTER CHROMATID EXCHANGE; TEA;

EID: 0035955460     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(01)01348-0     Document Type: Article

References (41)

1. The bacteriocidal activity of tea and coffee
2. The protective activity of tea against infection by Vibrio cholerae 01
3. Inhibition of influenza virus infection by tea
4. Inhibition of multiplication of influenza virus by extracts of tea
5. Antioxidative activity of tea leaf catechins
6. Protection against N-nitrosodiethylamine and benzo[a]pyrene-induced forestomach and lung tumorigenesis in A/J mice by green tea
7. Inhibition of 12-O-tetradecanoylphorbol-13-acetate-caused tumor promotion in 7,12-dimethylbenz[a]anthracene-initiated SENCAR mouse skin by a polyphenolic fraction isolated from green tea
8. Bio-antimutagenic activity of green tea catechins in cultured Chinese hamster V79 cells
9. Tea polyphenols as inhibitors of major classes of carcinogens
10. Relationship between antimutagenic activity and major components of various teas
11. Antimutagenicity and catechin content of soluble instant teas
12. Involvement of protein tyrosine phosphorylation in the effect of green tea polyphenols on Ehrlich ascites tumor cells in vitro
13. Cancer chemoprevention by tea polyphenols
14. The prevention of lung cancer by a tobacco specific carcinogen in rodents by green and black tea
15. Inhibition of angiogenesis and induction of endothelial and tumor cell apoptosis by green tea in animal models of human high grade non Hodgkin's lymphoma
16. Effects of tea and chlorophyllin on the mutagenicity of N-hydroxy-IQ: Studies of enzyme inhibition, molecular complex formation, and degradation/scavenging of the active metabolites
17. Antimutagenic activity of tea towards 2-hydroxyamino-3-methylimidazo[4,5-f]quinoline: Effect of tea towards 2-hydroxyamino-3-methylimidazo[4,5-f] quinoline: Effect of tea concentration and brew time on electrophile scavenging
18. A comparison of the antimutagenic potential of green, black and decaffeinated teas: Contribution of flavonols to the antimutagenic effect
19. Tea in chemoprevention of cancer: Epidemiological experimental studies
20. Genetic damage and the inhibition of 7,12-dimethylbenz[a]-anthracene induced genetic damage by the phytoestrogens, genistein and daidzein, in female ICR mice
21. Comparitive antimutagenic effects of d- and l- centchroman and their comparison with tamoxifen in Salmonella assay
22. Antimutagenic effects of centchroman and its enantiomers in Swiss albino mice. I. Acute study and their comparison with tamoxifen
23. In vitro antimutagenic effects of black tea (World blend) and its two active polyphenols theaflavins and thearubigins in Salmonella strains TA97a, TA98, TA100 and TA102
24. Antioxidative and antimutagenic effects of theaflavin from black tea
25. The relative anti-oxidant activities of plant-derived polyphenolic flavonoids
26. Prokinetic effect of black tea on gastrointestinal motility
27. Antioxidant properties of fractions and polyphenol constituents from green, oolong and black teas
28. Inhibition of 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine (PhIP) mutagenicity by black and green tea extracts and polyphenols
29. Mammalian in vivo cytogenetic assays: Analysis of chromosome aberrations in bone marrow cells
30. Improved sister chromatid differentiation using paraffin coated bromodeoxyuridine tablets in mice
31. New Giemsa method for the differential staining of sister chromatids
32. Average generation time: A new method for analyzing cellular proliferation kinetics based on bromodeoxyuridine-dependent chromosome differential staining patterns
33. A multiple comparison procedure for comparing several treatments with the control
34. Tea tannin components modify the induction of sister chromatid exchanges and chromosome aberrations in mutagen-treated cultured mammalian cells and mice
35. Effects of dietary consumption of black tea infusion alone and in combination with known clastogens on mouse bone marrow chromosomes in vivo
36. Contribution of theafulvins to the antimutagenicity of black tea: Their mechanism of action
37. Inhibitory activity of green and black tea in a free radical generating system using 2-amino-3-methylimidazo[4,5-b] quinoline as substrate
38. Catechin as antimutagen: Its mode of action
39. The electrophile counterattack response: Protection against neoplasia and toxicity