Insulin-like growth factor-1 protects H9c2 cardiac myoblasts from oxidative stress-induced apoptosis via phosphatidylinositol 3-kinase and extracellular signal-regulated kinase pathways

Life Sciences

Volumn 68, Issue 10, 2001, Pages 1095-1105

  Hong, Feng ^a   Kwon, Si Joong ^a   Jhun, Bong Sook ^b   Kim, Sung Soo ^a   Ha, Joohun ^a   Kim, Soo Ja ^b   Sohn, Nak Won ^b   Kang, Chulhun ^b   Kang, Insug ^a,b  

^a Kyung Hee University Hospital   (South Korea)

^b Kyung Hee University   (South Korea)

Author keywords

Bax expression; c jun N terminal kinase; H9c2 cardiac myoblasts; Insulin like growth factor 1 protection; Oxidative stress induced apoptosis; Phosphatidylinositol 3 kinase and extracellular signal regulated kinase

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAX; RAPAMYCIN; SOMATOMEDIN C; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME REGULATION; MYOBLAST; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELLS, CULTURED; ENZYME ACTIVATION; INSULIN-LIKE GROWTH FACTOR I; MITOGEN-ACTIVATED PROTEIN KINASE 8; MITOGEN-ACTIVATED PROTEIN KINASES; MYOCARDIUM; OXIDATIVE STRESS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS;

EID: 0035951395     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(00)01012-2     Document Type: Article

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