Dihydro(alkylthio)(naphthylmethyl)oxopyrimidines: Novel non-nucleoside reverse transcriptase inhibitors of the S-DABO series

Journal of Medicinal Chemistry

Volumn 40, Issue 10, 1997, Pages 1447-1454

  Mai, Antonello ^b   Artico, Marino ^b   Sbardella, Gianluca ^b   Quartarone, Silvana ^b   Massa, Silvio ^c   Loi, Anna G ^a   De Montis, Antonella ^a   Scintu, Franca ^a   Putzolu, Monica ^a   La Colla, Paolo ^a  

^a UNIVERSITY OF CAGLIARI   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c UNIVERSITY OF SIENA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

2 (CYCLOHEXYLTHIO) 3,4 DIHYDRO 3,5 DIMETHYL 6 (3' METHYLBENZYL) 4 OXOPYRIMIDINE; 2 (CYCLOHEXYLTHIO) 3,4 DIHYDRO 5 METHYL 4 OXO 6 (PHENOXYMETHYL)PYRIMIDINE; 2 (CYCLOHEXYLTHIO) 3,4 DIHYDRO 5 METHYL 6 (3' METHYLBENZYL) 4 THIOXOPYRIMIDINE; 2 (CYCLOHEXYLTHIO) 4 METHOXY 5 METHYL 6 (3' METHYLBENZYL)PYRIMIDINE; 2 CYCLOHEXYLTHIO 3,4 DIHYDRO 5 METHYL 6 (3 METHYLBENZYL) 4 PYRIMIDINONE; 3,4 DIHYDRO 2 [(1 METHYLPROPYL)THIO] 4 OXO 6 (1 NAPHTHYLMETHYL)PYRIMIDINE; 4 OXO 6 (PHENOXYMETHYL) 1,2,3,4 TETRAHYDRO 2 THIOXOPYRIMIDINE; ACETOACETIC ACID DERIVATIVE; METHYL GROUP; NEVIRAPINE; PYRIMIDINE; PYRIMIDINE DERIVATIVE; RNA DIRECTED DNA POLYMERASE INHIBITOR; SULFUR; THIOUREA; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CHEMICAL MODIFICATION; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION;

CELL LINE; HIV-1; HIV-1 REVERSE TRANSCRIPTASE; HIV-2; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; PYRIMIDINES; REVERSE TRANSCRIPTASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 15444340492     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960802y     Document Type: Article

References (23)

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