The replication timing program of the Chinese hamster β-globin locus is established coincident with its repositioning near peripheral heterochromatin in early G1 phase

Journal of Cell Biology

Volumn 154, Issue 2, 2001, Pages 283-292

  Li, Feng ^a   Chen, Jianhua ^a   Izumi, Masako ^b   Butler, Mark C ^a   Keezer, Susan M ^a   Gilbert, David M ^a  

^a State University of New York Upstate Medical University: College of Medicine   (United States)

^b INST OF PHYS AND CHEMICAL RESEARCH   (Japan)

Author keywords

globin; Cell cycle; DNA replication; Heterochromatin; Nuclear organization

Indexed keywords

BETA GLOBIN; DIHYDROFOLATE REDUCTASE;

ANIMAL CELL; ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL SYNCHRONIZATION; CHO CELL; CONTROLLED STUDY; GENE LOCATION; GENE LOCUS; GENE REPLICATION; HETEROCHROMATIN; MITOSIS; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BROMODEOXYURIDINE; CELL NUCLEUS; CHO CELLS; CRICETINAE; DNA; DNA REPLICATION; G1 PHASE; GLOBINS; HETEROCHROMATIN; IN SITU HYBRIDIZATION, FLUORESCENCE; MITOSIS; S PHASE; TETRAHYDROFOLATE DEHYDROGENASE; TIME FACTORS; XENOPUS;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS; RODENTIA;

EID: 0035939669     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200104043     Document Type: Article

References (52)

1. Chromatin dynamics in interphase nuclei and its implications for nuclear structure
2. Perinuclear localization of chromatin facilitates transcriptional silencing
3. Factors affecting the timing and imprinting of replication on a mammalian chromosome
4. Analysis of replication timing properties of human X-chromosomal loci by fluorescence in situ hybridization
5. Analysis of DNA replication by fluorescence in situ hybridization
6. Re-modeling of nuclear architecture in quiescent and senescent human fibroblasts
7. Rate of replication of the murine immunoglobulin heavy-chain locus: Evidence that the region is part of a single replicon
8. Dynamic repositioning of genes in the nucleus of lymphocytes preparing for cell division
9. Long-distance control of origin choice and replication timing in the human β-globin locus are independent of the locus control region
10. Nuclear compartments and gene regulation
11. Differences in the localization and morphology of chromosomes in the human nucleus
12. Genetic modification of heterochromatic association and nuclear organization in Drosophila
13. Large-scale chromosomal movements during interphase progression in Drosophila
14. Perturbation of nuclear architecture by long-distance chromosome interactions
15. The coordinate replication of the human β-globin gene domain reflects its transcriptional activity and nuclease hypersensitivity
16. Activation and repression of a β-globin gene in cell hybrids is accompanied by a shift in its temporal regulation
17. Regulation of mammalian replication origin usage in Xenopus egg extracts
18. DNA replication and nuclear organization: Prospects for a soluble in vitro system
19. The spatial position and replication timing of chromosomal domains are both established in early G1-phase
20. Asynchronous DNA replication within the human β-globin gene locus
21. Spatial organization of large-scale chromatin domains in the nucleus: A magnified view of single chromosome territories
22. A functional enhancer suppresses silencing of a transgene and prevents its localization close to centrometric heterochromatin
23. Positions of potential: Nuclear organization and gene expression
24. Temporal order of replication of Xenopus laevis 5S ribosomal RNA genes in somatic cells
25. Nuclear position leaves its mark on replication timing
26. Replication program of active and inactive multigene families in mammalian cells
27. The positioning and dynamics of origins of replication in the budding yeast nucleus
28. DNA replication-dependent intranuclear relocation of double minute chromatin
29. Replicon clusters are stable units of chromosome structure: Evidence that nuclear organization contributes to the efficient activation and propagation of S phase in human cells
30. Allele-specific replication timing of imprinted gene regions
31. Replication structure of the human β-globin gene domain
32. Cloning of two adult hamster globin cDNAs (α and β major)
33. Cloning and sequence analysis of two embryonic β-like globin cDNAs (y and z) of hamster
34. Interphase cell cycle dynamics of a late-replicating, heterochromatic homogeneously staining region: Precise choreography of condensation/decondensation and nuclear positioning
35. Spatial and temporal dynamics of DNA replication sites in mammalian cells
36. Dynamic behavior of DNA replication domains
37. Direct imaging of DNA in living cells reveals the dynamics of chromosome formation
38. Interphase chromosomes undergo constrained diffusional motion in living cells
39. Splitting the chromosome: Cutting the ties that bind sister chromatids
40. Dynamic organization of DNA replication in mammalian cell nuclei: Spatially and temporally defined replication of chromosome-specific α-satellite DNA sequences
41. The spatial distribution of human immunoglobulin genes within the nucleus: Evidence for gene topography independent of cell type and transcriptional activity
42. Nuclear localization and histone acetylation: A pathway for chromatin opening and transcriptional activation of the human β-globin locus
43. Delineation of DNA replication time zones by fluorescence in situ hybridization
44. Dynamic elastic behavior of α-satellite DNA domains visualized in situ in living human cells
45. The pattern of replication at a human relomeric region (16p13.3): Its relationship to chromosome structure and gene expression
46. Replication timing properties of the human HPRT locus on active, inactive and reactivated X chromosomes
47. Duplication and maintenance of heterochromatin domains
48. Temporal order of gene replication in Chinese hamster ovary cells
49. Interphase movements of a DNA chromosome region modulated by VP16 transcriptional activator
50. Segregation of transcription and replication sites into higher order domains
51. Origin-specific initiation of mammalian nuclear DNA replication in a Xenopus cell-free system
52. Structure and dynamics of human interphase chromosome territories in vivo