Design, synthesis, and biological activity of methoctramine-related polyamines as putative Gi protein activators

Journal of Medicinal Chemistry

Volumn 44, Issue 24, 2001, Pages 4035-4038

  Melchiorre, C ^a   Bolognesi, M L ^a   Budriesi, R ^a   Ghelardini, C ^b   Chiarini, A ^a   Minarini, A ^a   Rosini, M ^a   Tumiatti, V ^a   Wade, E J ^c  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b UNIVERSITY OF FLORENCE   (Italy)

^c GRÜNENTHAL GMBH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BENEXTRAMINE; BENZALKONIUM CHLORIDE; GUANINE NUCLEOTIDE BINDING PROTEIN; METHOCTRAMINE; MUSCARINIC RECEPTOR BLOCKING AGENT; POLYAMINE DERIVATIVE;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DESIGN; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTROSTIMULATION; GUINEA PIG; HEART LEFT ATRIUM; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANIMALS; ATRIAL FUNCTION; CHO CELLS; CRICETINAE; DIAMINES; DRUG DESIGN; ELECTRIC STIMULATION; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GUINEA PIGS; HEART ATRIA; HUMANS; MUSCARINIC AGONISTS; POLYAMINES; RATS; RECEPTORS, MUSCARINIC; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035935710     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0155594     Document Type: Article

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