Ref-1 and transcriptional control of endothelial apoptosis

Circulation Research

Volumn 88, Issue 12, 2001, Pages 1223-1225

  Wang, Nanping ^a   Stemerman, Michael B ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Apoptosis; Endothelium; Oxidative stress; Transcription factor

Indexed keywords

APOPTOSIS; CONTROL SYSTEM; EDITORIAL; ENDOTHELIUM CELL; MOLECULAR CLONING; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; TRANSCRIPTION REGULATION; VASCULAR ENDOTHELIUM;

EID: 0035933430     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/hh1201.093162     Document Type: Editorial

References (30)

1. Endothelial cells in physiology and in the pathophysiology of vascular disorders
2. Endothelial apoptosis: Could it have a role in the pathogenesis and treatment of disease?
3. Endothelial cell apoptosis in angiogenesis and vessel regression
4. Overexpression of Ref-1 inhibits hypoxia and tumor necrosis factor-induced endothelial cell apoptosis through nuclear factor-κB-independent and -dependent pathways
5. Cloning and expression of APE, the cDNA encoding the major human apurinic endonuclease: Definition of a family of DNA repair enzymes
6. Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity
7. Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme
8. Two different cellular redox systems regulate the DNA-binding activity of the p50 subunit of NF-κB in vitro
9. Ref-1 regulates the transactivation and pro-apoptotic functions of p53 in vivo
10. Identification of redox/repair protein Ref-1 as a potent activator of p53
11. Molecular mechanisms of transcription activation by HLF and HIFlα in response to hypoxia: Their stabilization and redox signal-induced interaction with CBP/p300
12. Analysis of c-Fos and c-Jun redox-dependent DNA binding activity
13. Reduction of apurinic/apyrimidinic endonuclease expression after transient global cerebral ischemia in rats: Implication of the failure of DNA repair in neuronal apoptosis
14. Glutaredoxin protects cerebellar granule neurons from dopamine-induced apoptosis by activating NF-κB via Ref-1
15. NF-κB: Pivotal mediator or innocent bystander in atherogenesis?
16. An essential role for NF-κB in preventing TNF-α-induced cell death
17. Protective genes expressed in endothelial cells: A regulatory response to injury
18. NF-κB activation is required for human endothelial survival during exposure to tumor necrosis factor-α but not to interleukin-1β or lipopolysaccharide
19. Mechanisms of hypoxia-induced endothelial cell death: Role of p53 in apoptosis
20. L serve an anti-inflammatory function in endothelial cells through inhibition of NF-κB
21. Failure to regulate TNF-induced NF-κB and cell death responses in A20-deficient mice
22. AP-1 function and regulation
23. c-Jun triggers apoptosis in human vascular endothelial cells
24. Sustained JNK activation induces endothelial apoptosis: Studies with colchicine and shear stress
25. Mildly oxidized low density lipoprotein activates multiple apoptotic signaling pathways in human coronary cells
26. Mechanisms of hypoxia-induced endothelial cell death: Role of p53 in apoptosis
27. Molecular mechanism of endothelial growth arrest by laminar shear stress
28. Going APE over ref-1
29. Accelerated death of retinal microvascular cells in human and experimental diabetic retinopathy
30. Human transplant coronary artery disease: Pathological evidence for Fas-mediated apoptotic cytotoxicity in allograft arteriopathy