Sustained JNK activation induces endothelial apoptosis: Studies with colchicine and shear stress

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 277, Issue 4 46-4, 1999, Pages

  Hu, Ying Li ^a   Li, Song ^a   Shyy, John Y J ^a   Chien, Shu ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cell death; Endothelial cells

Indexed keywords

COLCHICINE; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DNA NICK TRANSLATION; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; MICROTUBULE; NONHUMAN; PRIORITY JOURNAL; SHEAR STRESS; SWINE;

EID: 0032716312     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1999.277.4.h1593     Document Type: Article

References (27)

1. Allen, T. D., J. H. Scarffe, and D. Crowther. Ultrastructural aspects of colchicine ultrasensitivity in CLL lymphocytes. Blood Cells 1: 147-160, 1981.
2. Bonfoco, E., S. Ceccatelli, L. Manzo, and P. Nicotera. Colchicine induces apoptosis in cerebellar granule cells. Exp. Cell Res. 218: 189-200, 1995.
3. Bossy-Wetzel, E., L. Bakiri, and M. Yaniv. Induction of apoptosis by the transcription factor c-Jun. EMBO J. 16: 1695-1709, 1997.
4. Bumbasirevic, V., V. Lackovic, and M. Japundzic. Enhancement of apoptosis in lymphoid tissue by microtubule disrupting drugs. IRCS Med. Sci. 13: 1257-1259, 1985.
5. Chen, Y. R., X. Wang, D. Templeton, R. J. Davis, and T. H. Tan. The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and γ radiation. Duration of JNK activation may determine cell death and proliferation. J. Biol. Chem. 271: 31929-31936, 1996.
6. Coan, D. E., A. R. Wechezak, R. F. Viggers, and L. R. Sauvage. Effect of shear stress upon localization of the Golgi apparatus and microtubule organizing center in isolated cultured endothelial cells. J. Cell Sci. 104: 1145-1153, 1993.
7. Cohen, J. J. Apoptosis. Immunol. Today 14: 126-130, 1993.
8. Derijard, B., M. Hibi, I. H. Wu, T. Barrett, B. Su, T. Deng, M. Karin, and R. J. Davis. JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell 76: 1025-1037, 1994.
9. Dewey, C. J., S. R. Bussolari, M J. Gimbrone, and P. F. Davies. The dynamic response of vascular endothelial cells to fluid shear stress. J. Biomech. Eng. 103: 177-185, 1981.
10. Dimmeler, S., J. Haendeler, V. Rippmann, M. Nehls, and A. M. Zeiher. Shear stress inhibits apoptosis of human endothelial cells. FEBS Lett. 399: 71-74, 1996.
11. Eskin, S. G., C. L. Ives, J. A. Frangos, and L. V. McIntire. Cultured endothelium: the response to flow. ASAIO J. 8: 109-112, 1985.
12. Galbraith, C. G., R. Skalak, and S. Chien. Shear stress induces spatial reorganization of the endothelial cell cytoskeleton. Cell Motil. Cytoskeleton 40: 317-330, 1998.
13. Ijiri, K., and C. S. Potten. Further studies on the response of intestinal crypt cells of different hierarchical status to eighteen different cytotoxic agents. Br. J. Cancer 55: 113-123, 1987.
14. Ingber, D. E. Cellular tensegrity: defining new rules of biological design that govern the cytoskeleton. J. Clin. Invest. 92: 1706-1712, 1993.
15. Kidd, V. J. Proteolytic activities that mediate apoptosis. Annu. Rev. Physiol. 60: 533-573, 1998.
16. Kolesnick, R. N., and M. Kronke. Regulation of ceramide production and apoptosis. Annu. Rev. Physiol. 60: 643-665, 1998.
17. Li, Y. S., J. Y. Shyy, S. Li, J. Lee, B. Su, M. Karin, and S. Chien. The Ras-JNK pathway is involved in shear-induced gene expression. Mol. Cell. Biol. 16: 5947-5954, 1996.
18. Malek, A. M., and S. Izumo. Mechanism of endothelial cell shape change and cytoskeletal remodeling in response to fluid shear stress. J. Cell Sci. 109: 713-726, 1996.
19. Malek, A. M., and S. Izumo. Molecular aspects of signal transduction of shear stress in the endothelial cell. J. Hypertens. 12: 989-999, 1994.
20. Martin, S. J., and T. G. Cotter. Specific loss of microtubules in HL-60 cells leads to programmed cell death (apoptosis). Biochem. Soc. Trans. 18: 299-301, 1990.
21. Steller, H. Mechanisms and genes of cellular suicide. Science 267: 1445-1449, 1995.
22. Thompson, C. B. Apoptosis in the pathogenesis and treatment of disease. Science 267: 1456-1462, 1995.
23. Tsukidate, K., K. K. Yamamoto, J. W. Snyder, and J. L. Farber. Microtubule antagonists activate programmed cell death (apoptosis) in cultured rat hepatocytes. Am. J. Pathol. 143: 918-925, 1993.
24. Verheij, M., R. Bose, X. H. Lin, B. Yao, W. D. Jarvis, S. Grant, M. J. Birrer, E. Szabo, L. I. Zon, and J. M. Kyriakis. Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis. Nature 380: 75-79, 1996.
25. Wechezak, A. R., R. F. Viggers, and L. R. Sauvage. Fibronectin and F-actin redistribution in cultured endothelial cells exposed to shear stress. Lab. Invest. 53: 639-647, 1985.
26. Wyllie, A. H., J. F. Kerr, and A. R. Currie. Cell death: the significance of apoptosis. Int. Rev. Cytol. 68: 251-306, 1980.
27. Yang, X., R. Khosravi-Far, H. Y. Chang, and D. Baltimore. Daxx, a novel Fas-binding protein that activates JNK and apoptosis. Cell 89: 1067-1076, 1997.