Traceless solid-phase synthesis of 2,4-diaminoquinazolines

Organic Letters

Volumn 3, Issue 4, 2001, Pages 585-588

  Wilson, Lawrence J ^a,b  

^a PROCTER AND GAMBLE PHARMACEUTICALS   (United States)

^b JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,4 DIAMINOQUINAZOLINE; 2,4-DIAMINOQUINAZOLINE; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; AMINE; ISOTHIOCYANIC ACID; ISOTHIOCYANIC ACID DERIVATIVE; NITRILE; PLANT RESIN; PRAZOSIN; QUINAZOLINE DERIVATIVE;

ARTICLE; CHEMISTRY; CYCLIZATION; SYNTHESIS;

ADRENERGIC ALPHA-ANTAGONISTS; AMINES; CYCLIZATION; ISOTHIOCYANATES; NITRILES; PRAZOSIN; QUINAZOLINES; RESINS, PLANT;

EID: 0035932065     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol006987r     Document Type: Article

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13. -1.
14. 2H) of a white solid.
15. 3COH: C, 49.10; H, 4.26; N, 13.32. Found: C, 49.35; H, 4.39; N, 13.03.
16. 6-DMSO): 3.76 (s, 7H), 3.81 (s, 7 H), 6.6 (quart, 1H, J = 1.7 Hz), 7.0 (d, 1H, 7 = 3.4 Hz), 7.08 (bs, 1H), 7.55 (bs, 1H), 7.8 (d, 1H, J = 1 Hz).