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Volumn 39, Issue 29, 1998, Pages 5135-5138

Solid phase synthesis of 1-aminohydantoin libraries

Author keywords

[No Author keywords available]

Indexed keywords

1 AMINOHYDANTOIN; ALDEHYDE; AMINE; ANTIARRHYTHMIC AGENT; ANTIINFECTIVE AGENT; AZIMILIDE; DANTROLENE; DRUG CARRIER; NITROFURANTOIN; UNCLASSIFIED DRUG;

EID: 0032537666     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(98)01009-0     Document Type: Article
Times cited : (50)

References (22)
  • 1
    • 4243965641 scopus 로고    scopus 로고
    • 1. (a) The thematic combinatorial issue of Chemical Reviews: Chem. Rev. 1997, 97(2);
    • (1997) Chem. Rev. , vol.97 , Issue.2
  • 17
    • 0025338421 scopus 로고
    • 1=Me, Et, i-Bu, i-Pr, Bn) using the method according to Hoffman, R.V.; Kim, H.-O. Tetrahedron Lett. 1990, 31, 2953-2956. This gives the option of introducing chirality at the alpha carbon, however racemic starting materials were utilized in each case.
    • (1990) Tetrahedron Lett. , vol.31 , pp. 2953-2956
    • Hoffman, R.V.1    Kim, H.-O.2
  • 21
    • 0010337505 scopus 로고    scopus 로고
    • note
    • 2: C, 50.6; H, 4.98; N, 18.38. Found: C, 50.1; H, 4.73; N, 17.9.
  • 22
    • 0010384793 scopus 로고    scopus 로고
    • note
    • 11. For entry 13, phenyl alanine was utilized as the silylated (TMS) ester by first heating the acid in bis(trimethylsilyl)acetamide (BSA, 3 equiv., DMF, 80°C), followed by cooling to room temperature, and then addition of the solution directly to the resin (step h, Scheme 1). Also, DMAP was used in place of DIPEA.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.