Encapsulation in biodegradable microparticles enhances serum antibody response to parenterally-delivered β-amyloid in mice

Vaccine

Volumn 19, Issue 30, 2001, Pages 4185-4193

  Brayden, David J ^a   Templeton, Louise ^a   McClean, Siobhan ^a   Barbour, Robin ^b   Huang, Jiping ^b   Nguyen, Minh ^b   Ahern, Deirdra ^a   Motter, Ruth ^b   Johnson Wood, Kelly ^b   Vasquez, Nicki ^b   Schenk, Dale ^b   Seubert, Peter ^b  

^a TRINITY COLLEGE DUBLIN   (Ireland)

^b ELAN PHARMACEUTICALS   (United States)

Author keywords

Amyloid; Adjuvants; Alzheimer's disease; Poly(lactide co glycolide)

Indexed keywords

AMYLOID BETA PROTEIN; BUFFER; IMMUNOMODULATING AGENT; LEUPRORELIN; MICROSPHERE; PHOSPHATE; POLYGLACTIN; PROTEIN ANTIBODY; RESOMER; SODIUM CHLORIDE;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY BLOOD LEVEL; ANTIBODY RESPONSE; ANTIBODY SPECIFICITY; ARTICLE; BIODEGRADATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG DELIVERY SYSTEM; DRUG EFFECT; DRUG EFFICACY; DRUG FORMULATION; ENCAPSULATION; MOUSE; NONHUMAN; PARTICLE SIZE; PASSIVE IMMUNIZATION; PRIORITY JOURNAL; SERUM;

AMYLOID BETA-PROTEIN; ANIMALS; ANTIBODIES; BIODEGRADATION, ENVIRONMENTAL; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; IMMUNIZATION; MICE; MICROSPHERES; PARTICLE SIZE; POLYGLACTIN 910;

EID: 0035919528     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(01)00162-1     Document Type: Article

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