메뉴 건너뛰기




Volumn 14, Issue 15, 1996, Pages 1429-1438

Single dose, polymeric, microparticle-based vaccines: The influence of formulation conditions on the magnitude and duration of the immune response to a protein antigen

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; IMMUNOGLOBULIN G; MICROSPHERE; OVALBUMIN; POLYMER; VACCINE;

EID: 0030445728     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(96)00077-1     Document Type: Article
Times cited : (82)

References (35)
  • 1
    • 0026548699 scopus 로고
    • Controlled release vaccines-biodegradable polylactide/polyglycolide (PL/PG) microspheres as antigen vehicles
    • 1 Aguado, M.T. and Lambert, P.H. Controlled release vaccines-biodegradable polylactide/polyglycolide (PL/PG) microspheres as antigen vehicles. Immunobiology 1992, 184, 113-125
    • (1992) Immunobiology , vol.184 , pp. 113-125
    • Aguado, M.T.1    Lambert, P.H.2
  • 2
    • 0028837225 scopus 로고
    • Comparison of 24 different adjuvants for inactivated HIV-2 split whole virus as antigen in mice. Induction of titres of binding antibodies and toxicity of the formulations
    • 2 Stieneker, F., Kersten, G., van Bloois, L. et al. Comparison of 24 different adjuvants for inactivated HIV-2 split whole virus as antigen in mice. Induction of titres of binding antibodies and toxicity of the formulations. Vaccine 1995, 13, 45-53
    • (1995) Vaccine , vol.13 , pp. 45-53
    • Stieneker, F.1    Kersten, G.2    Van Bloois, L.3
  • 3
    • 0027305289 scopus 로고
    • Long term antibody responses in mice following subcutaneous immunisation with ovalbumin entrapped in biodegradable microparticles
    • 3 O'Hagan, D.T., Jeffery, H. and Davis, S.S. Long term antibody responses in mice following subcutaneous immunisation with ovalbumin entrapped in biodegradable microparticles. Vaccine 1993, 11, 965-969
    • (1993) Vaccine , vol.11 , pp. 965-969
    • O'Hagan, D.T.1    Jeffery, H.2    Davis, S.S.3
  • 4
    • 0028321707 scopus 로고
    • Dose and load studies for subcutaneous and oral delivery of poly(lactide co-glycolide) microspheres containing ovalbumin
    • 4 Uchida, T., Martin, S., Foster, T.P., Wardley, R.C. and Grimm, S. dose and load studies for subcutaneous and oral delivery of poly(lactide co-glycolide) microspheres containing ovalbumin. Pharm. Res. 1994, 11, 1009-1015
    • (1994) Pharm. Res. , vol.11 , pp. 1009-1015
    • Uchida, T.1    Martin, S.2    Foster, T.P.3    Wardley, R.C.4    Grimm, S.5
  • 5
    • 0028876363 scopus 로고
    • Synthetic delivery systems for tuberculosis vaccines: Immunological evaluation of the M. tuberculosis 38 kDa protein entrapped in biodegradable PLG microparticles
    • 5 Vordermeier, M., Coombes, A.G.A., Jenkins, P. et al. Synthetic delivery systems for tuberculosis vaccines: immunological evaluation of the M. tuberculosis 38 kDa protein entrapped in biodegradable PLG microparticles. Vaccine 1995, 13, 1576-1582
    • (1995) Vaccine , vol.13 , pp. 1576-1582
    • Vordermeier, M.1    Coombes, A.G.A.2    Jenkins, P.3
  • 6
    • 0027169876 scopus 로고
    • Determinants of release rate of tetanus vaccine from polyester microspheres
    • 6 Alonso, M.J., Cohen, S., Park, T.J. and Langer, R.S. Determinants of release rate of tetanus vaccine from polyester microspheres. Pharm. Res. 1993, 10, 945-953
    • (1993) Pharm. Res. , vol.10 , pp. 945-953
    • Alonso, M.J.1    Cohen, S.2    Park, T.J.3    Langer, R.S.4
  • 7
    • 0026636415 scopus 로고
    • Parameters affecting, the immunogenicity of microencapsulated tetanus toxoid
    • 7 Espartza, I. and Kissel, T. Parameters affecting, the immunogenicity of microencapsulated tetanus toxoid. Vaccine 1992, 10, 714-720
    • (1992) Vaccine , vol.10 , pp. 714-720
    • Espartza, I.1    Kissel, T.2
  • 8
    • 0002581377 scopus 로고
    • Biodegradable delivery system for single step immunisatuion with tetanus toxoid
    • 8 Raghuvanshi, R.S., Singh, M. and Talwar, G.P. Biodegradable delivery system for single step immunisatuion with tetanus toxoid. Int. J. Pharm. 1993, 93, R1-R5
    • (1993) Int. J. Pharm. , vol.93
    • Raghuvanshi, R.S.1    Singh, M.2    Talwar, G.P.3
  • 9
    • 0026658789 scopus 로고
    • Immunogenicity studies on diptheria toxoid loaded biodegradable microspheres
    • 9 Singh, M., Singh, O., Singh, A. and Talwar, G.P. Immunogenicity studies on diptheria toxoid loaded biodegradable microspheres. Int. J. Pharm. 1992, 85, R5-R8
    • (1992) Int. J. Pharm. , vol.85
    • Singh, M.1    Singh, O.2    Singh, A.3    Talwar, G.P.4
  • 11
    • 0028578108 scopus 로고
    • Resorbable synthetic polymers as replacements for bone graft
    • 11 Coombes, A.G.A. and Meikle, M.C. Resorbable synthetic polymers as replacements for bone graft. Clin. Mater. 1994, 17, 35-67
    • (1994) Clin. Mater. , vol.17 , pp. 35-67
    • Coombes, A.G.A.1    Meikle, M.C.2
  • 12
    • 0025292580 scopus 로고
    • Two-ply biodegradable nerve guide: Basic aspects of design, construction and biological performance
    • 12 Hoppen, H.J., Leenslag, J.W., Pennings, A.J., Van der Lei, B. and Robinson, P.H. Two-ply biodegradable nerve guide: basic aspects of design, construction and biological performance. Biomaterials 1990, 11, 286-290
    • (1990) Biomaterials , vol.11 , pp. 286-290
    • Hoppen, H.J.1    Leenslag, J.W.2    Pennings, A.J.3    Van Der Lei, B.4    Robinson, P.H.5
  • 13
    • 0017714158 scopus 로고
    • Use of vicryl (polyglactin 910) sutures in general surgical and cardiothoracic procedures
    • 13 Reul, G.J. Use of vicryl (polyglactin 910) sutures in general surgical and cardiothoracic procedures. Am. J. Surg. 1977, 134, 297
    • (1977) Am. J. Surg. , vol.134 , pp. 297
    • Reul, G.J.1
  • 15
    • 0025053154 scopus 로고
    • Biodegradable poly(lactic acid) and poly(lactide co-glycolide) microcapsules: Problems associated with preparative techniques and release properties
    • 15 Jalil, R. and Nixon, J.R. Biodegradable poly(lactic acid) and poly(lactide co-glycolide) microcapsules: problems associated with preparative techniques and release properties. J. Microencaps. 1990, 7, 297-325
    • (1990) J. Microencaps. , vol.7 , pp. 297-325
    • Jalil, R.1    Nixon, J.R.2
  • 17
    • 0023901210 scopus 로고
    • A new technique to efficiently entrap leuprolide acetate into microcapsules of copolylactic/glycolic acid
    • 17 Ogawa, Y., Yamamoto, M., Okada, H., Yashiki, T. and Shimamoto, T. A new technique to efficiently entrap leuprolide acetate into microcapsules of copolylactic/glycolic acid. Chem. Pharm. Bull. 1988, 36, 1095-1103
    • (1988) Chem. Pharm. Bull. , vol.36 , pp. 1095-1103
    • Ogawa, Y.1    Yamamoto, M.2    Okada, H.3    Yashiki, T.4    Shimamoto, T.5
  • 19
    • 0028140194 scopus 로고
    • The preparation and characterisation of poly(lactide co-glycolide) microparticles. 3, microparticle/polymer degradation rates and the in vitro release of a model protein
    • 19 O'Hagan, D.T., Jeffery, H. and Davis, S.S. The preparation and characterisation of poly(lactide co-glycolide) microparticles. 3, Microparticle/polymer degradation rates and the in vitro release of a model protein. Int. J. Pharm. 1994, 103, 37-45
    • (1994) Int. J. Pharm. , vol.103 , pp. 37-45
    • O'Hagan, D.T.1    Jeffery, H.2    Davis, S.S.3
  • 20
    • 0022186670 scopus 로고
    • Measurement of protein using bicinchoninic acid
    • 20 Smith, P.K. et al. Measurement of protein using bicinchoninic acid. Analyt. Biochem. 1985, 150, 76
    • (1985) Analyt. Biochem. , vol.150 , pp. 76
    • Smith, P.K.1
  • 21
    • 0026654831 scopus 로고
    • Enhanced secretory IgA and systemic IgG antibody responses after oral immunisation with biodegradable microparticles containing antigen
    • 21 Challacombe, S.J., Rahman, D., Jeffery, H., Davis, S.S. and O'Hagan, D.T. Enhanced secretory IgA and systemic IgG antibody responses after oral immunisation with biodegradable microparticles containing antigen. Immunology 1992, 76, 164-168
    • (1992) Immunology , vol.76 , pp. 164-168
    • Challacombe, S.J.1    Rahman, D.2    Jeffery, H.3    Davis, S.S.4    O'Hagan, D.T.5
  • 22
    • 0027988425 scopus 로고
    • In-vitro characterisation of biodegradable microparticles for oral antigen delivery
    • 22 Russell-Jones, G.J. and Jeffery, H. In-vitro characterisation of biodegradable microparticles for oral antigen delivery. Proc. Int. Symp. Contr. Rel. Bioact. Mater. 1994, 21, 873-874
    • (1994) Proc. Int. Symp. Contr. Rel. Bioact. Mater. , vol.21 , pp. 873-874
    • Russell-Jones, G.J.1    Jeffery, H.2
  • 23
    • 0027643021 scopus 로고
    • Adsorption/desorption of human serum albumin at the surface of poly(lactic acid) nanoparticles prepared by a solvent evaporation process
    • 23 Verrechia, T., Huve, P., Bazile, D., Veillard, M., Spenlehauer, G. and Couvreur, P. Adsorption/desorption of human serum albumin at the surface of poly(lactic acid) nanoparticles prepared by a solvent evaporation process. J. Biomed. Mater. Res. 1993, 27, 1019-1028
    • (1993) J. Biomed. Mater. Res. , vol.27 , pp. 1019-1028
    • Verrechia, T.1    Huve, P.2    Bazile, D.3    Veillard, M.4    Spenlehauer, G.5    Couvreur, P.6
  • 24
    • 0002514969 scopus 로고
    • Immunopotentiation and delivery systems for antigens for single-step immunisation
    • 24 Khan, M.Z.I., Optebeeck, J.P. and Tucker, I.G. Immunopotentiation and delivery systems for antigens for single-step immunisation. Recent Trends Progr. Pharm. Res. 1994, 11, 2-11
    • (1994) Recent Trends Progr. Pharm. Res. , vol.11 , pp. 2-11
    • Khan, M.Z.I.1    Optebeeck, J.P.2    Tucker, I.G.3
  • 25
    • 0023761867 scopus 로고
    • B-cell memory is short lived in the absence of antigen
    • 25 Gray, D. and Skarvall, H. B-cell memory is short lived in the absence of antigen. Nature 1988, 336, 70
    • (1988) Nature , vol.336 , pp. 70
    • Gray, D.1    Skarvall, H.2
  • 26
    • 0019740466 scopus 로고
    • Polymers for the sustained release of macromolecules. Their use in a single step method of immunisation
    • 26 Langer, R. Polymers for the sustained release of macromolecules. Their use in a single step method of immunisation. Meth. Enzym. 1981, 73, 57-75
    • (1981) Meth. Enzym. , vol.73 , pp. 57-75
    • Langer, R.1
  • 27
    • 0028911017 scopus 로고
    • Importance of in vitro experimental conditions on protein release kinetics, stability and polymer degradation in protein encapsulated poly(DL lactic acid co-glycolic acid) microspheres
    • 27 Park, T.G., Lu, W.L. and Crotts, G. Importance of in vitro experimental conditions on protein release kinetics, stability and polymer degradation in protein encapsulated poly(DL lactic acid co-glycolic acid) microspheres. J. Contr. Rel. 1995, 33, 211-222
    • (1995) J. Contr. Rel. , vol.33 , pp. 211-222
    • Park, T.G.1    Lu, W.L.2    Crotts, G.3
  • 28
    • 0020507831 scopus 로고
    • 6, LHRH a decapeptide onto glass and other surfaces
    • 6, LHRH a decapeptide onto glass and other surfaces. Int. J. Pharm. 1983, 16, 181-190
    • (1983) Int. J. Pharm. , vol.16 , pp. 181-190
    • Anick, S.T.1    Hwang, J.Y.2
  • 29
    • 0028234449 scopus 로고
    • The influence of biodegradable microcapsule formulations on the controlled release of a protein
    • 29 Sah, H., Toddywala, R. and Chien, Y.W. The influence of biodegradable microcapsule formulations on the controlled release of a protein. J. Contr. Release 1994, 30, 201-211
    • (1994) J. Contr. Release , vol.30 , pp. 201-211
    • Sah, H.1    Toddywala, R.2    Chien, Y.W.3
  • 30
    • 0028065467 scopus 로고
    • Identification of some of the physico-chemical characteristics of microspheres which influence the induction of the immune response following mucosal delivery
    • 30 Alpar, H.O. and Almeida, A.J. Identification of some of the physico-chemical characteristics of microspheres which influence the induction of the immune response following mucosal delivery. Eur. J. Pharm. Biopharm. 1994, 40, 198-202
    • (1994) Eur. J. Pharm. Biopharm. , vol.40 , pp. 198-202
    • Alpar, H.O.1    Almeida, A.J.2
  • 31
    • 0026100291 scopus 로고
    • Adjuvant activity of non-ionic block copolymers.IV Effect of molecular weight and formulation on titre and isotype of antibody
    • 31 Hunter, R., Olsen, M. and Buynitzky, S. Adjuvant activity of non-ionic block copolymers.IV Effect of molecular weight and formulation on titre and isotype of antibody. Vaccine 1991, 9, 250-256
    • (1991) Vaccine , vol.9 , pp. 250-256
    • Hunter, R.1    Olsen, M.2    Buynitzky, S.3
  • 32
    • 0023938397 scopus 로고
    • Influence of hydrophobicity on the adjuvant effect of particulate polymeric adjuvants
    • 32 Kreuter, J., Liehl, E., Berg, U., Soliva, M. and Speiser, P.P. Influence of hydrophobicity on the adjuvant effect of particulate polymeric adjuvants. Vaccine 1988, 6, 253-256
    • (1988) Vaccine , vol.6 , pp. 253-256
    • Kreuter, J.1    Liehl, E.2    Berg, U.3    Soliva, M.4    Speiser, P.P.5
  • 33
    • 0025834747 scopus 로고
    • Biodegradable and biocompatible poly(dl lactide co-glycolide) microspheres as an adjuvant for Staphylococcal Enterotoxin B toxoid which enhances the level of toxin-neutralising antibodies
    • 33 Eldridge, J.H., Staas, J.K., Meulbroek, J.A., Tice, T.R. and Gilley, R.M. Biodegradable and biocompatible poly(dl lactide co-glycolide) microspheres as an adjuvant for Staphylococcal Enterotoxin B toxoid which enhances the level of toxin-neutralising antibodies. Infect. Immun. 1991, 59, 2978-2986
    • (1991) Infect. Immun. , vol.59 , pp. 2978-2986
    • Eldridge, J.H.1    Staas, J.K.2    Meulbroek, J.A.3    Tice, T.R.4    Gilley, R.M.5
  • 34
    • 0024650737 scopus 로고
    • Protein precoating of polylactide microspheres containing a lipophilic immunopotentiator for enhancement of macrophage phagocytosis and activation
    • 34 Tabata, Y. and Ikada, Y. Protein precoating of polylactide microspheres containing a lipophilic immunopotentiator for enhancement of macrophage phagocytosis and activation. Pharm. Res. 1989, 6, 296-301
    • (1989) Pharm. Res. , vol.6 , pp. 296-301
    • Tabata, Y.1    Ikada, Y.2
  • 35
    • 0025872120 scopus 로고
    • The pharmacokinetics of and humoral response to antigen delivered by microencapsulated liposomes
    • 35 Cohen, S., Bernstein, C., Hewes, C., Chow, M. and Langer, R. The pharmacokinetics of and humoral response to antigen delivered by microencapsulated liposomes. Proc. Natl. Acad. Sci. USA 1991, 88, 10440-10444
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 10440-10444
    • Cohen, S.1    Bernstein, C.2    Hewes, C.3    Chow, M.4    Langer, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.