Recombinant glycoprotein product quality in proliferation-controlled BHK-21 cells

Biotechnology and Bioengineering

Volumn 65, Issue 5, 1999, Pages 529-536

  Mueller, Peter P ^a   Schlenke, Peter ^a   Nimtz, Manfred ^a   Conradt, Harald S ^a   Hauser, Hansjörg ^a  

^a HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

Author keywords

Baby hamster kidney (BHK) cells; IRF 1; Proliferation control; Recombinant human erythropoietin glycosylation

Indexed keywords

DRUG PRODUCTS; PROTEINS;

GLYCOSYLATION; PHARMACEUTICAL PROTEIN; RECOMBINANT GLYCOPROTEIN;

ANIMAL CELL CULTURE;

ERYTHROPOIETIN; ESTRADIOL; GLYCOPROTEIN; HYBRID PROTEIN; RECOMBINANT PROTEIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; BIOENGINEERING; CELL PROLIFERATION; CELL SECRETION; CELL STRAIN BHK; DRUG MANUFACTURE; GROWTH RATE; GROWTH REGULATION; NONHUMAN; PROTEIN SECRETION;

ANIMALS; BIOTECHNOLOGY; CARBOHYDRATE SEQUENCE; CELL DIVISION; CELL LINE; CRICETINAE; DNA-BINDING PROTEINS; ERYTHROPOIETIN, RECOMBINANT; GLYCOPROTEINS; GLYCOSYLATION; HUMANS; INTERFERON REGULATORY FACTOR-1; MOLECULAR SEQUENCE DATA; OLIGOSACCHARIDES; PHOSPHOPROTEINS; PROTEIN ENGINEERING; QUALITY CONTROL; RECOMBINANT PROTEINS;

ANIMALIA; CRICETINAE; MAMMALIA;

EID: 0033527911     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0290(19991205)65:5<529::AID-BIT5>3.0.CO;2-M     Document Type: Article

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