Approaches for generating recombinant adenovirus vectors

Advanced Drug Delivery Reviews

Volumn 52, Issue 3, 2001, Pages 165-176

  Mizuguchi, Hiroyuki ^a   Kay, Mark A ^b   Hayakawa, Takao ^a  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adenovirus vector; Fiber; Gene regulation; Gene therapy; Targeting; Tetracycline

Indexed keywords

BACTERIA; CELLS; GENES; MUTAGENS;

CELL LINES;

CONTROLLED DRUG DELIVERY;

RECOMBINANT DNA; VIRUS VECTOR;

ADENOVIRUS; BACTERIUM; GENE TRANSFER; GENETIC RECOMBINATION; GENETIC TRANSFECTION; LIGATION; MUTANT; NONHUMAN; PRIORITY JOURNAL; REVIEW; VIRUS RECOMBINANT;

ADENOVIRIDAE; ANIMALS; DNA, RECOMBINANT; GENETIC VECTORS; HUMANS; RECOMBINATION, GENETIC;

EID: 0035915058     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-409X(01)00215-0     Document Type: Review

References (67)

1. Adenoviridae
2. Characteristics of a human cell line transformed by DNA from human adenovirus type 5
3. Characterization of 911: A new helper cell line for the titration and propagation of early region 1-deleted adenoviral vectors
4. Helper cells and matched early region 1-deleted adenovirus vectors prevent generation of replication-competent adenoviruses
5. An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3
6. Packaging capacity and stability of human adenovirus type 5 vectors
7. Gene therapy: Adenovirus vectors
8. Adenoviral vectors for gene transfer
9. Adenovirus vectors for gene delivery
10. Advances in adenoviral vectors: From genetic engineering to their biology
11. Generation of adenovirus by transfection of plasmids
12. Expression of human alpha 1-antitrypsin using a recombinant adenovirus vector
13. Adenovirus-mediated transfer of a recombinant alpha 1-antitrypsin gene to the lung epithelium in vivo
14. Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genome
15. A simplified system for generating recombinant adenoviruses
16. Efficient generation of recombinant adenovirus vectors by homologous recombination in Escherichia coli
17. Recombinational construction in Escherichia coli of infectious adenoviral genomes
18. Efficient construction of a recombinant adenovirus vector by an improved in vitro ligation method
19. A simple method for constructing E1 and E1/E4 deleted recombinant adenovirus vector
20. Cleavage pattern of the homing endonuclease encoded by the fifth intron in the chloroplast large subunit rRNA-encoding gene of Chlamydomonas eugametos
21. Homing of a DNA endonuclease gene by meiotic gene conversion in Saccharomyces cerevisiae
22. Novel cloning method for recombinant adenovirus construction in Escherichia coli
23. Efficient manipulation of the human adenovirus genome as an infectious yeast artificial chromosome clone
24. Efficient generation of recombinant adenoviral vectors by Cre-lox recombination in vitro
25. Construction of adenovirus vectors through Cre-lox recombination
26. A high-efficiency Cre-loxP-based system for construction of adenoviral vectors
27. An enhanced system for construction of adenoviral vectors by the two-plasmid rescue method
28. Constructing adenoviral vectors by using the circular form of the adenoviral genome cloned in a cosmid and the Cre-loxP recombination system
29. A simple method for the rapid generation of recombinant adenovirus vectors
30. New vectors for the construction of double recombinant adenoviruses
31. New tools for the generation of E1- and/or E3-substituted adenoviral vectors
32. Use of the cosmid adenoviral vector cloning system for the in vitro construction of recombinant adenoviral vectors
33. Generation of recombinant adenovirus vector with infectious adenoviral genome released from cosmid-based vector by simple procedure allowing complex manipulation
34. Efficient directional cloning of recombinant adenovirus vectors using DNA-protein complex
35. Transcriptional interference in avian retroviruses-implications for the promoter insertion model of leukaemogenesis
36. Genes with promoters in retrovirus vectors can be independently suppressed by an epigenetic mechanism
37. Quantitative analysis of gene suppression in integrated retrovirus vectors
38. Construction of a double recombinant adenovirus vector expressing a heterodimeric cytokine: In vitro and in vivo production of biologically active interleukin-12
39. In vitro ligation-based cloning of foreign DNAs into the E3 and E1 deletion region for generation of recombinant adenovirus vector
40. Recognition and cleavage site of the intron-encoded omega transposase
41. Purification and characterization of the in vitro activity of I-Sce I, a novel and highly specific endonuclease encoded by a group I intron
42. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
43. Development and characterization of a binary gene expression system based on bacteriophage T7 components in adenovirus vectors
44. Interleukin 12 and B7-1 costimulatory molecule expressed by an adenovirus vector act synergistically to facilitate tumor regression
45. Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5
46. Differential susceptibility of primary and established human glioma cells to adenovirus infection: Targeting via the epidermal growth factor receptor achieves fiber receptor-independent gene transfer
47. Limited entry of adenovirus vectors into well-differentiated airway epithelium is responsible for inefficient gene transfer
48. Lack of high affinity fiber receptor activity explains the resistance of ciliated airway epithelia to adenovirus infection
49. HCAR and MCAR: The human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses
50. Mutations that alter an Arg-Gly-Asp (RGD) sequence in the adenovirus type 2 penton base protein abolish its cell-rounding activity and delay virus reproduction in flat cells
51. Integrins αvβ3 and αvβ5 promote adenovirus internalization but not virus attachment
52. Integrin αvβ5 selectively promotes adenovirus mediated cell membrane permeabilization
53. Poly-lysine modification of adenoviral fiber protein enhances muscle cell transduction
54. Increased gene transfer in acute myeloid leukemic cells by an adenovirus vector containing a modified fiber protein
55. Increased in vitro and in vivo gene transfer by adenovirus vectors containing chimeric fiber proteins
56. Generation of fiber-mutant recombinant adenoviruses for gene therapy of malignant glioma
57. An adenovirus vector with genetically modified fibers demonstrates expanded tropism via utilization of a Coxsackievirus and adenovirus receptor-independent cell entry mechanism
58. Characterization of an adenovirus vector containing a heterologous peptide epitope in the HI loop of the fiber knob
59. Insertion of an RDG motif into the HI loop of adenovirus fiber protein alters the distribution of transgene expression of the systemically administered vector
60. A simplified system for constructing recombinant adenoviral vectors containing heterologous peptides in the HI loop of their fiber knob
61. Domains required for assembly of adenovirus type 2 fiber trimers
62. Crystal structure of the receptor-binding domain of adenovirus type 5 fiber protein at 1.7 A resolution
63. Structure of the receptor binding domain of adenovirus type 5 fiber protein
64. Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model
65. Alpha v integrins as receptors for tumor targeting by circulating ligands
66. Phage libraries displaying cyclic peptides with different ring sizes: Ligand specificities of the RGD-directed integrins
67. Targeting adenovirus