Rearrangement of Side-chains in a Zif268 Mutant Highlights the Complexities of Zinc Finger-DNA Recognition

Journal of Molecular Biology

Volumn 313, Issue 2, 2001, Pages 309-315

  Miller, Jeffrey C ^a   Pabo, Carl O ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Crystal structure; DNA binding protein; Sequence specificity; Zif268; Zinc finger

Indexed keywords

DNA; DNA BINDING PROTEIN; TRANSCRIPTION FACTOR; WATER; ZINC FINGER PROTEIN;

ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; CONFORMATION; ENZYME SPECIFICITY; GENETICS; METABOLISM; NUCLEOTIDE SEQUENCE; POINT MUTATION; PROTEIN BINDING; PROTEIN SECONDARY STRUCTURE; THERMODYNAMICS; X RAY CRYSTALLOGRAPHY;

BASE SEQUENCE; BINDING SITES; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; DNA; DNA-BINDING PROTEINS; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; POINT MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; SUBSTRATE SPECIFICITY; THERMODYNAMICS; TRANSCRIPTION FACTORS; WATER; ZINC FINGERS;

EID: 0035914475     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2001.4975     Document Type: Article

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