Reperfusion following focal cerebral ischemia alters distribution of neuronal cells with DNA fragmentation in mice

Brain Research

Volumn 751, Issue 1, 1997, Pages 160-164

  Murakami, Kensuke ^a   Kondo, Takeo ^a   Chan, Pak H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

DNA fragmentation; focal cerebral ischemia; reperfusion injury; TUNEL staining

Indexed keywords

DNA FRAGMENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN ISCHEMIA; CONTROLLED STUDY; HISTOLOGY; MALE; MOUSE; NERVE CELL; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BIOTIN; BRAIN ISCHEMIA; CELL DEATH; CEREBRAL INFARCTION; DEOXYURACIL NUCLEOTIDES; DNA FRAGMENTATION; MALE; MICE; MICE, INBRED STRAINS; NEURONS; REPERFUSION INJURY; STAINING AND LABELING;

EID: 0030901498     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(97)00029-2     Document Type: Article

References (18)

1. Chan, P.H., Role of oxidants in ischemic brain damage, Stroke, 27 (1996) 1124-1129.
2. Copin, J.-C., Reola, L.F., Chan, T.Y.Y., Li, Y., Epstein, C.J. and Chan, P.H., Oxygen deprivation but not a combination of oxygen, glucose, and serum deprivation induces DNA degradation in mouse cortical neurons in vitro: Attenuation by transgenic overexpressing of CuZn-superoxide dismutase, J. Neurotrauma, 13 (1996) 233-244.
3. Ferrer, I., Martin, F., Serrano, T., Reiriz, J., Perez-Navarro, E., Alberch, J., Macaya, A. and Planas, A.M., Both apoptosis and necrosis occur following intrastriatal administration of excitotoxins, Acta Neuropathol. (Berl.), 90 (1995) 504-510.
4. Greenlund, L.J., Deckwerth, T.L. and Johnson, E.M., Jr., Superoxide dismutase delays neuronal apoptosis: a role for reactive oxygen species in programmed neuronal death, Neuron, 14 (1995) 303-315.
5. Haraldsson, G., Nilsson, U., Bratell, S., Pettersson, S., Schersten, T., Akerlund, S. and Jonsson, O., ESR-measurement of production of oxygen radicals in vivo before and after renal ischaemia in the rabbit, Acta Physiol. Scand., 146 (1992) 99-105.
6. Hockenbery, D., Nunez, G., Milliman, C., Schreiber, R.D. and Korsmeyer, S.J., Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death, Nature, 348 (1990) 334-336.
7. Hockenbery, D.M., Oltvai, Z.N., Yin, X.M., Milliman, C.L. and Korsmeyer, S.J., Bcl-2 functions in an antioxidant pathway to prevent apoptosis, Cell, 75 (1993) 241-251.
8. Kane, D.J., Sarafian, T.A., Anton, R., Hahn, H., Gralla, E.B., Valentine, J.S., Ord, T. and Bredesen, D.E., Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species, Science, 262 (1993) 1274-1277.
9. Li, Y., Chopp, M., Jiang, N., Yao, F. and Zaloga, C., Temporal profile of in situ DNA fragmentation after transient middle cerebral artery occlusion in the rat, J. Cereb. Blood Flow Metab., 15 (1995) 389-397.
10. Linnik, M.D., Miller, J.A., Sprinkle-Cavallo, J., Mason, P.J., Thompson, F.Y., Montgomery, L.R. and Schroeder, K.K., Apoptotic DNA fragmentation in the rat cerebral cortex induced by permanent middle cerebral artery occlusion, Mol. Brain Res., 32 (1995) 116-124.
11. MacManus, J.P., Buchan, A.M., Hill, I.E., Rasquinha, I. and Preston, E., Global ischemia can cause DNA fragmentation indicative of apoptosis in rat brain, Neurosci. Lett., 164 (1993) 89-92.
12. Mitchell, I.J., Lawson, S., Moser, B., Laidlaw, S.M., Cooper, A.J., Walkinshaw, G. and Waters, C.M., Glutamate-induced apoptosis results in a loss of striatal neurons in the parkinsonian rat, Neuroscience, 63 (1994) 1-5.
13. Nagasawa, H. and Kogure, K., Correlation between cerebral blood flow and histologic changes in a new rat model of middle cerebral artery occlusion, Stroke, 20 (1989) 1037-1043.
14. Nitatori, T., Sato, N., Waguri, S., Karasawa, Y., Araki, H., Shibanai, K., Kominami, E. and Uchiyama, Y., Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis, J. Neurosci., 15 (1995) 1001-1011.
15. Pollard, H., Charriaut-Marlangue, C., Cantagrel, S., Represa, A., Robain, O., Moreau, J. and Ben-Ari, Y., Kainate-induced apoptotic cell death in hippocampal neurons, Neuroscience, 63 (1994) 7-18.
16. Portera-Cailliau, C., Hedreen, J.C., Price, D.L. and Koliatsos, V.E., Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models, J. Neurosci., 15 (1995) 3775-3787.
17. Rink, A., Fung, K.M., Trojanowski, J.Q., Lee, V.M., Neugebauer, E. and McIntosh, T.K., Evidence of apoptotic cell death after experimental traumatic brain injury in the rat, Am. J. Pathol., 147 (1995) 1575-1583.
18. Yang, G., Chan, P.M., Chen, J., Carlson, E., Chen, S.F., Weinstein, P., Epstein, C.J. and Kamii, H., Human copper-zinc superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia, Stroke, 25 (1994) 165-170.