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Volumn 40, Issue 37, 2001, Pages 10956-10965
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How does a DNA interacting enzyme change its specificity during molecular evolution? A site-directed mutagenesis study at the DNA binding site of the DNA-(adenine-N6)-methyltransferase EcoRV
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Author keywords
[No Author keywords available]
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Indexed keywords
MUTATIONS;
ENZYMES;
MOLECULAR DYNAMICS;
MUTAGENESIS;
DNA;
ADENINE;
DNA;
DNA ADENINE METHYLTRANSFERASE;
ARTICLE;
BINDING SITE;
CONTROLLED STUDY;
DNA BINDING;
DNA METHYLATION;
DNA SEQUENCE;
ENZYME SPECIFICITY;
ENZYME STRUCTURE;
ESCHERICHIA COLI;
MOLECULAR EVOLUTION;
MOLECULAR RECOGNITION;
NONHUMAN;
PHYLOGENY;
PLASMID;
PRIORITY JOURNAL;
PROTEIN DNA INTERACTION;
SEQUENCE HOMOLOGY;
SITE DIRECTED MUTAGENESIS;
STRUCTURE ACTIVITY RELATION;
STRUCTURE ANALYSIS;
AMINO ACID SEQUENCE;
BINDING SITES;
DNA-BINDING PROTEINS;
EVOLUTION, MOLECULAR;
METHYLATION;
MODELS, CHEMICAL;
MODELS, MOLECULAR;
MOLECULAR SEQUENCE DATA;
MUTAGENESIS, SITE-DIRECTED;
PHYLOGENY;
SEQUENCE HOMOLOGY, AMINO ACID;
SITE-SPECIFIC DNA-METHYLTRANSFERASE (ADENINE-SPECIFIC);
SUBSTRATE SPECIFICITY;
VARIATION (GENETICS);
ESCHERICHIA COLI;
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EID: 0035909057
PISSN: 00062960
EISSN: None
Source Type: Journal
DOI: 10.1021/bi0155450 Document Type: Article |
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Times cited : (18)
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References (46)
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