Single Nucleotide Polymorphism of Human Platelet-activating Factor Receptor Impairs G-protein Activation

Journal of Biological Chemistry

Volumn 276, Issue 46, 2001, Pages 43025-43030

  Fukunaga, Kouichi ^a   Ishii, Satoshi ^c   Asano, Koichiro ^a   Yokomizo, Takehiko ^b,c   Shiomi, Tetsuya ^a   Shimizu, Takao ^b,c   Yamaguchi, Kazuhiro ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DISEASES; DNA; GENES; MUTAGENESIS; PROTEINS;

PHENOTYPES;

BIOCHEMISTRY;

ADENYLATE CYCLASE; ALANINE; APAFANT; ASPARTIC ACID; CALCIUM; GUANINE NUCLEOTIDE BINDING PROTEIN; INOSITOL PHOSPHATE; THROMBOCYTE ACTIVATING FACTOR RECEPTOR; ADENYLATE CYCLASE TOXIN; ANTITHROMBOCYTIC AGENT; AZEPINE DERIVATIVE; BORDETELLA VIRULENCE FACTOR; CELL SURFACE RECEPTOR; CYCLIC AMP; FIBRINOGEN RECEPTOR; FORSKOLIN; G PROTEIN COUPLED RECEPTOR; LIGAND; TRIAZOLE DERIVATIVE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CALCIUM MOBILIZATION; CELL LINE; CHEMOTAXIS; CHO CELL; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME INHIBITION; GENE FREQUENCY; HUMAN; HUMAN CELL; JAPAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; ALLELE; ANIMAL; CHEMISTRY; DOSE RESPONSE; DRUG ANTAGONISM; GENETIC POLYMORPHISM; GENETIC TRANSFECTION; GENETICS; HAMSTER; KINETICS; METABOLISM; MOLECULAR GENETICS; MUTATION; PHENOTYPE; PROTEIN BINDING; RADIOASSAY;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS;

ADENYLATE CYCLASE; ADENYLATE CYCLASE TOXIN; ALANINE; ALLELES; AMINO ACID SEQUENCE; ANIMALS; ASPARTIC ACID; AZEPINES; CELL LINE; CHEMOTAXIS; CHO CELLS; CRICETINAE; CYCLIC AMP; DOSE-RESPONSE RELATIONSHIP, DRUG; FORSKOLIN; GTP-BINDING PROTEINS; HUMANS; INOSITOL PHOSPHATES; KINETICS; LIGANDS; MOLECULAR SEQUENCE DATA; MUTATION; PHENOTYPE; PLATELET AGGREGATION INHIBITORS; PLATELET MEMBRANE GLYCOPROTEINS; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN BINDING; RADIOLIGAND ASSAY; RECEPTORS, CELL SURFACE; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; TRANSFECTION; TRIAZOLES; VIRULENCE FACTORS, BORDETELLA;

EID: 0035900781     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M108288200     Document Type: Article

References (34)

1. Honda, Z., Nakamura, M., Miki, I., Minami, M., Watanabe, T., Seyama, Y., Okado, H., Toh, H., Ito, K., Miyamoto, T., and Shimizu, T. (1991) Nature 349, 342-346
2. Nakamura, M., Honda, Z., Izumi, T., Sakanaka, C., Mutoh, H., Minami, M., Bito, H., Seyama, Y., Matsumoto, T., Noma, M., and Shimizu, T. (1991) J. Biol. Chem. 266, 20400-20405
3. Ishii, S., and Shimizu, T. (2000) Prog. Lipid Res. 39, 41-82
4. Rodiiguez-Roisin, R., Felez, M. A., Chung, K. F., Barbera, J. A., Wagner, P. D., Cobos, A., Barnes, P. J., and Roca, J. (1994) J. Clin. Invest. 93, 188-194
5. Longphre, M., Zhang, L. Y., Paquette, N., and Kleeberger, S. R. (1996) Am. J. Respir. Cell Mol. Biol. 14, 461-469
6. Brzustowicz, L. M., Gardner, J. P., Hopp, L., Jeanclos, E., Ott, J., Yang, X. Y., Fekete, Z., and Aviv, A. (1997) Hypertension 29, 158-164
7. Prescott, S. M., Zimmerman, G. A., Stafforini, D. M., and McIntyre, T. M. (2000) Annu. Rev. Biochem. 69, 419-445
8. Grynkiewicz, G., Poenie, M., and Tsien, R. Y. (1985) J. Biol. Chem. 260, 3440-3450
9. Martin, T. F. (1983) J. Biol. Chem. 258, 14816-14822
10. Yokomizo, T., Izumi, T., Chang, K., Takuwa, Y., and Shimizu, T. (1997) Nature 387, 620-624
11. Honda, Z., Takano, T., Gotoh, Y., Nishida, E., Ito, K., and Shimizu, T. (1994) J. Biol. Chem. 269, 2307-2315
12. Prescott, S. M., Zimmerman, G. A., and McIntyre, T. M. (1990) J. Biol. Chem. 265, 17381-17384
13. Hanahan, D. J. (1986) Annu. Rev. Biochem. 55, 483-509
14. Strader, C. D., Dixon, R. A., Cheung, A. H., Candelore, M. R., Blake, A. D., and Sigal, I. S. (1987) J. Biol. Chem. 262, 16439-16443
15. Blin, N., Yun, J., and Wess, J. (1995) J. Biol. Chem. 270, 17741-17748
16. van Biesen, T., Hawes, B. E., Raymond, J. R., Luttrell, L. M., Koch, W. J., and Lefkowitz, R. J. (1996) J. Biol. Chem. 271, 1266-1269
17. Ali, H., Richardson, R. M., Tomhave, E. D., DuBose, R. A., Haribabu, B., and Snyderman, R. (1994) J. Biol. Chem. 269, 24557-24563
18. Shi, L. C., Wang, H. Y., Horwitz, J., and Friedman, E. (1996) J. Neurochem. 67, 1478-1484
19. Carlson, S. A., Chatterjee, T. K., Murphy, K. P., and Fisher, R. A. (1998) Mol. Pharmacol. 53, 451-458
20. Parent, J. L., Le Gouill, C., de Brum-Fernandes, A. J., Rola-Pleszczynski, M., and Stankova, J. (1996) J. Biol. Chem. 271, 7949-7955
21. Small, K. M., Brown, K. M., Forbes, S. L., and Liggett, S. B. (2001) J. Biol. Chem. 276, 4917-4922
22. Small, K. M., Forbes, S. L., Brown, K. M., and Liggett, S. B. (2000) J. Biol. Chem. 275, 38518-38523
23. Small, K. M., Forbes, S. L., Rahman, F. F., Bridges, K. M., and Liggett, S. B. (2000) J. Biol. Chem. 275, 23059-23064
24. Jin, T., Zhang, N., Long, Y., Parent, C. A., and Devreotes, P. N. (2000) Science 287, 1034-1036
25. Ishii, S., Nagase, T., Tashiro, F., Ikuta, K., Sato, S., Waga, I., Kume, K., Miyazaki, J., and Shimizu, T. (1997) EMBO J. 16, 133-142
26. Nagase, T., Ishii, S., Kume, K., Uozumi, N., Izumi, T., Ouchi, Y., and Shimizu, T. (1999) J. Clin. Invest. 104, 1071-1076
27. Ishii, S., Kuwaki, T., Nagase, T., Maki, K., Tashiro, F., Sunaga, S., Cao, W. H., Kume, K., Fukuchi, Y., Ikuta, K., Miyazaki, J., Kumada, M., and Shimizu, T. (1998) J. Exp. Med. 187, 1779-1788
28. Miwa, M., Miyake, T., Yamanaka, T., Sugatani, J., Suzuki, Y. Sakata, S., Araki, Y., and Matsumoto, M. (1988) J. Clin. Invest. 82, 1983-1991
29. Stafforini, D. M., Satoh, K., Atkinson, D. L., Tjoelker, L. W., Eberhardt, C., Yoshida, H., Imaizumi, T., Takamatsu, S., Zimmerman, G. A., McIntyre, T. M., Gray, P. W., and Prescott, S. M. (1996) J. Clin. Invest. 97, 2784-2791
30. Yamada, Y., Ichihara, S., Fujimura, T., and Yokota, M. (1998) Metabolism 47, 177-181
31. Hiramoto, M., Yoshida, H., Imaizumi, T., Yoshimizu, N., and Satoh, K. (1997) Stroke 28, 2417-2420
32. Tanaka, R., Iijima, K., Xu, H., Inoue, Y., Murakami, R., Shirakawa, T., Nishiyama, K., Miwa, M., Shiozawa, S., Nakamura, H., and Yoshikawa, N. (1999) Am. J. Kidney Dis. 34, 289-295
33. Stafforini, D. M., Numao, T., Tsodikov, A., Vaitkus, D., Fukuda, T., Watanabe, N., Fueki, N., McIntyre, T. M., Zimmerman, G. A., Makino, S., and Prescott, S. M. (1999) J. Clin. Invest. 103, 989-997
34. Satoh, N., Asano, K., Naoki, K., Fukunaga, K., Iwata, M., Kanazawa, M., and Yamaguchi, K. (1999) Am. J. Respir. Crit. Care Med. 159, 974-979