The topoisomerase II poison clerocidin alkylates non-paired guanines of DNA: Implications for irreversible stimulation of DNA cleavage

Nucleic Acids Research

Volumn 29, Issue 20, 2001, Pages 4224-4230

  Gatto, Barbara ^a   Richter, Sara ^a   Moro, Stefano ^a   Capranico, Giovanni ^b   Palumbo, Manlio ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; CLEROCIDIN; DITERPENOID; DNA; DNA TOPOISOMERASE (ATP HYDROLYSING); GUANINE; NITROGEN; NUCLEIC ACID; OLIGONUCLEOTIDE; PLASMID DNA; SINGLE STRANDED DNA; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ALKYLATION; ANTIBACTERIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; BASE PAIRING; CHEMICAL STRUCTURE; COMPLEX FORMATION; CONTROLLED STUDY; COVALENT BOND; DNA CLEAVAGE; DNA STRAND BREAKAGE; DNA SUPERCOILING; DRUG STRUCTURE; EXPOSURE; HEAT; IN VITRO STUDY; INTOXICATION; MAMMAL; PRIORITY JOURNAL; STIMULATION;

EID: 0035886451     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/29.20.4224     Document Type: Article

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