Se-methylselenocysteine induces apoptosis mediated by reactive oxygen species in HL-60 cells

Free Radical Biology and Medicine

Volumn 31, Issue 4, 2001, Pages 479-489

  Jung, Uhee ^a   Zheng, Xuexiu ^a   Yoon, Sang Oh ^a   Chung, An Sik ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

Apoptosis; Caspase; Cytochrome c; Free radicals; Reactive oxygen species; Se methylselenocysteine

Indexed keywords

ACETYLCYSTEINE; CASPASE 3; CASPASE 9; CYTOCHROME C; DNA FRAGMENT; FREE RADICAL; REACTIVE OXYGEN METABOLITE; SE METHYLSELENOCYSTEINE; SELENIUM DERIVATIVE; UNCLASSIFIED DRUG;

ANALYTIC METHOD; APOPTOSIS; ARTICLE; CELL POPULATION; CELL STRAIN HL 60; CELL VIABILITY; CHEMOPROPHYLAXIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG UPTAKE; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN SECRETION;

ACETYLCYSTEINE; ANTICARCINOGENIC AGENTS; ANTIOXIDANTS; APOPTOSIS; BLOTTING, WESTERN; CASPASES; CELL SURVIVAL; CYSTEINE; CYTOCHROME C GROUP; ENZYME ACTIVATION; FLOW CYTOMETRY; HELA CELLS; HL-60 CELLS; HUMANS; MEMBRANE POTENTIALS; ORGANOSELENIUM COMPOUNDS; REACTIVE OXYGEN SPECIES;

EID: 0035882266     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(01)00604-9     Document Type: Article

References (70)

1. Comparison of selenium and sulfur analogs in cancer prevention
2. Cellular and metabolic effects of triphenylselenonium chloride in a mammary cell culture model
3. Effects of 1,4-phenylenebis(methylene)selenocyanate and selenomethionine on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced tumorigenesis in A/J mouse lung
4. Efficacy of cancer prevention by high-selenium garlic is primarily dependent on the action of selenium
5. Chemopreventive agents: Selenium
6. Selenium metabolism, selenoproteins and mechanisms of cancer prevention: Complexities with thioredoxin reductase
7. Comparative effects of phenylenebis(methylene)selenocyanate isomers on xenobiotic metabolizing enzymes in organs of female CD rats
8. Activity of methylated forms of selenium in cancer prevention
9. Chemical form of selenium, critical metabolites, and cancer prevention
10. Comparative effect of inorganic and organic selenocyanate derivatives in mammary cancer chemoprevention
11. Selenium modulation of cell proliferation and cell cycle biomarkers in normal and premalignant cells of the rat mammary gland
12. Characterization of tissue selenium profiles and anticarcinogenic responses in rats fed natural sources of selenium-rich products
13. Inhibition of cdk2 kinase activity by methylselenocysteine in synchronized mouse mammary epithelial tumor cells
14. Effects of methylselenocysteine on PKC activity, cdk2 phosphorylation and gadd gene expression in synchronized mouse mammary epithelial tumor cells
15. In vitro and in vivo studies of methylselenic acid: Evidence that a monomethylated selenium metabolite is critical for cancer chemoprevention
16. 2 cells
17. Dual role of glutathione in selenite-induced oxidative stress and apoptosis in human hepatoma cells
18. Induction of apoptosis by selenite and selenodiglutathione in HL-60 cells: Correlation with cytotoxicity
19. Apoptosis and disease
20. Apoptosis: A different type of cell death
21. Caspases: Enemies within
22. Role of reactive oxygen species in apoptosis: Implications for cancer therapy
23. Cytotoxic mechanism of tumor necrosis factor-alpha
24. Role of peroxide and superoxide anion during tumour cell apoptosis
25. Hydrogen peroxide suppresses U937 cell death by two different mechanisms depending on its concentration
26. Requirement of caspase-3(-like) protease-mediated hydrogen peroxide production for apoptosis induced by various anticancer drugs
27. Ajoene, a compound of garlic, induces apoptosis in human promyeloleukemic cells, accompanied by generation of reactive oxygen species and activation of Nuclear Factor kB
28. The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage
29. Tumor growth inhibition, apoptosis, and Bcl-2 down-regulation of MCF-7ras tumors by sodium phenylacetate and tamoxifen combination
30. Dissociation of the genotoxic and growth inhibitory effects of selenium
31. Selenite induction of DNA strand breaks and apoptosis in mouse leukemic L1210 cells
32. Fluorometric determination of selenium in nanogram amounts in biological materials using 2,3-diaminonaphthalene
33. Endogenous endonuclease-induced DNA fragmentation: An early event in cell-mediated cytolysis
34. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
35. Simultaneous release of adenylate kinase and cytochrome c in cell death
36. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
37. Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization
38. Caspase-8 mediates caspase-3 activation and cytochrome c release during singlet oxygen-induced apoptosis in HL-60 cells
39. Apoptosis induction by caspase-8 is amplified through the mitochondrial release of cytochrome c
40. The biochemistry of cell death by apoptosis
41. Simultaneous genetic chemoprotection of normal marrow cells and genetic chemosensitization of breast cancer cells in a mouse cancer gene therapy model
42. Se-methylselenocysteine induces apoptosis through caspase activation in HL-60 cells
43. Effect of an aqueous extract of selenium-enriched garlic on in vitro markers and in vivo efficacy in cancer prevention
44. In vitro effects of Se-allylselenocysteine and Se-propylselenocysteine on cell growth, DNA integrity, and apoptosis
45. Activity of Se-allylselenocysteine in the presence of methionine g-lyase on cell growth, DNA integrity, apoptosis and cell-cycle regulatory molecules
46. Discovery of natural product chemopreventive agents utilizing HL-60 cell differentiation as a model
47. Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer drugs: A cautionary note
48. DNA fragmentation induced by protease activation in p53-null human leukemia HL60 cells undergoing apoptosis following treatment with the topoisomerase I inhibitor camptothecin: Cell-free system studies
49. Granzyme B-induced loss of mitochondrial inner membrane potential (Delta Psi m) and cytochrome c release are caspase independent
50. Caspase-dependent and -independent death of camptothecin-treated embryonic cortical neurons
51. Caspases: The executioners of apoptosis
52. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
53. Cytochrome c-dependent and -independent induction of apoptosis in multiple myeloma cells
54. Anandamide induces apoptosis of PC-12 cells: Involvement of superoxide and caspase-3
55. p38 mitogen-activated protein kinase mediates bid cleavage, mitochondrial dysfunction, and caspase-3 activation during apoptosis induced by singlet oxygen but not by hydrogen peroxide
56. Dual regulation of caspase activity by hydrogen peroxide: Implications for apoptosis
57. Activation of caspase 3 in HL-60 cells exposed to hydrogen peroxide
58. Induction of the mitochondrial permeability transition causes release of the apoptogenic factor cytochrome c
59. Cytochrome c release and caspase activation in hydrogen peroxide- and tributyltin-induced apoptosis
60. Oxidative stress as a necessary factor in room temperature-induced apoptosis of HL-60 cells
61. Active oxygen generation by the reaction of selenite with reduced glutathione in vitro
62. Generation of reactive oxygen species from the reaction of selenium compounds with thiols and mammary tumor cells
63. Comparative cytotoxicity of 14 novel selenocysteine Se-conjugates in rat renal proximal tubular cells
64. Chemoprevention of mammary cancer with Se-allylselenocysteine and other selenoamino acids in the rat
65. Quantifying cellular oxidative stress by dichlorofluorescein assay using microplate reader
66. Induction of oxidative DNA damage in u937 cells by TNF or anti-Fas stimulation
67. 2+-dependent isoenzymes of Protein Kinase C
68. AP-1 DNA-binding activity is inhibited by selenite and selenodiglutathione
69. Inhibition of NF-κB DNA binding and nitric oxide induction in human T cells and lung adenocarcinoma cells by selenite treatment