Signaling through MHC class II molecules blocks CD95-induced apoptosis

Journal of Immunology

Volumn 166, Issue 10, 2001, Pages 6019-6024

  Catlett, Ian M ^a   Xie, Ping ^a   Hostager, Bruce S ^a   Bishop, Gail A ^a,b,c  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FAS ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ANIMAL CELL; ANTIGEN PRESENTATION; APOPTOSIS; ARTICLE; B LYMPHOCYTE; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

EID: 0035873030     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.166.10.6019     Document Type: Article

References (55)

1. Schattner, E. J., K. B. Eldon, D.-H. Yoo, J. Tumang, P. H. Krammer, M. K. Crow, and S. M. Friedman. 1995. CD40 ligation induces Fas expression on human B lymphocytes and facilitates apoptosis through the Fas pathway. J. Exp. Med. 182:1557.
2. + T cells. Nature 376:181.
3. Rathmell, J. C., S. E. Townsend, J. C. Xu, R. A. Flavell, and C. C. Goodnow. 1996. Expansion or elimination of B cells in vivo: dual roles for CD40- and CD95-ligands modulated by the B cell antigen receptor. Cell 87:319.
4. Callett, I. M., and G. A. Bishop. 1999. Cutting edge: a novel mechanism for rescue of B cells from CD95/Fas-mediated apoptosis. J. Immunol. 163:2378.
5. Cleary, A. M., S. M. Fortune, M. J. Yellin, L. Chess, and S. Lederman. 1995. Opposing roles of CD95 (Fas/APO-1) and CD40 in the death and rescue of human low density tonsillar B cells. J. Immunol. 155:3329.
6. Foote, L. C., R. G. Howard, A. Marshak-Rothstein, and T. L. Rothstein. 1996. IL-4 induces Fas resistance in B cells. J. Immunol. 157:2749.
7. Koizumi, T., J. Wang, Y. Suzuki, K. Masuda, and T. Watanabe. 1996. Regulation of bcl-xL expression and Fas susceptibility in mouse B cells by CD40 ligation, surface IgM crosslinking and IL-4. Mol. Immunol. 33:1247.
8. Schneider, T. J., D. Grillot, L. C. Foote, G. E. Núñez, and T. L. Rothstein. 1997. Bcl-x protects primary B cells against Fas-mediated apoptosis. J. Immunol. 159:4834.
9. Irmler, M., M. Thome, M. Hahne, P. Schneider, K. Hofmann, V. Steiner, J. Bodmer, M. Schröter, K. Burns, C. Mattmann, et al. 1997. Inhibition of death receptor signals by cellular FLIP. Nature 387:190.
10. Schneider, T. J., G. M. Fischer, T. J. Donohoe, T. P. Colarusso, and T. L. Rothstein. 1999. A novel gene coding for a Fas apoptosis inhibitory molecule (FAIM) isolated from inducibly Fas-resistant B lymphocytes. J. Exp. Med. 189:949.
11. Sarma, V., Z. Lin, L. Clark, B. M. Rust, M. Tewari, R. J. Noelle, and V. M. Dixit. 1995. Activation of the B-cell surface receptor CD40 induces A20, a novel zinc finger protein that inhibits apoptosis. J. Biol. Chem. 270:12343.
12. Chinnaiyan, A. M., C. G. Tepper, M. F. Seldin, K. O'Rourke, F. C. Kischkel, S. Hellbardt, P. H. Krammer, M. E. Peter, and V. M. Dixit. 1996. FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and TNFR-induced apoptosis. J. Biol. Chem. 271:4961.
13. Zhang, J., and A. Winoto. 1996. A mouse Fas-associated protein with homology to the human FADD protein is essential for Fas-induced apoptosis. Mol. Cell. Biol. 16:2756.
14. Muzio, M., A. M. Chinnaiyan, F. C. Kischkel, K. O'Rourke, A. Shevchenko, J. Ni, C. Scaffidi, J. D. Bretz, M. Zhang, R. Gentz, et al. 1996. FLICE, a novel FADD-homologous ICE-CED-3-like protease, is recruited to the CD95 (Fas/ APO-1) death-inducing signaling complex. Cell 85:817.
15. Imai, Y., T. Kimura, A. Murakami, N. Yajima, K. Sakamaki, and S. Yonehara. 1999. The CED-4-homologous protein FLASH is involved in Fas-mediated activation of caspase-8 during apoptosis. Nature 398:777.
16. Zhang, J., D. Cado, A. Chen, N. H. Kabra, and A. Wintot. 1998. Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1. Nature 392:296.
17. Varfolomeev, E. E., M. Schuchmann, V. Luria, N. Chiannikulchai, J. S. Beckmann, I. L. Mett, D. Rebrikov, V. M. Brodianski, O. C. Kemper, O. Kollet, et al. 1998. Targeted disruption of the mouse caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally. Immunity 9:267.
18. Thornberry, N. A., T. A. Rano, E. P. Peterson, D. M. Rasper, T. Timkey, M. Garcia-Calvo, V. M. Houtzager, P. A. Nordstrom, S. Roy, J. P. Vaillancourt, et al. 1997. A combinatorial approach defines specificities of members of the caspase family and granzyme B: functional relationships established for key mediators of apoptosis. J. Biol. Chem. 272:17907.
19. Medema, J. P., C. Scaffidi, F. C. Kischkel, A. Shevchenko, M. Mann, P. H. Krammer, and M. E. Peter. 1997. FLICE is activated by association with the DISC. EMBO J. 16:2794.
20. Hirata, H., A. Takahashi, S. Kobayashi, S. Yonehara, H. Sawai, T. Okazaki, K. Yamamoto, and M. Sasada. 1998. Caspases are activated in a branched protease cascade and control distinct downstream processes in Fas-induced apoptosis. J. Exp. Med. 187:587.
21. Memon, S. A., J. Hou, M. B. Boreno, and C. M. Zacharchuk. 1998. Apoptosis induced by a chimeric Fas/FLICE receptor: lack of requirement for Fas or FADD-binding proteins. J. Immunol. 160:2046.
22. Mourad, W., R. S. Geha, and T. Chatila. 1990. Engagement of MHC class II molecules induces sustained, LFA-1-dependent cell adhesion. J. Exp. Med. 172:1513.
23. Altomonte, M., C. Pucillo, G. Damante, and M. Maio. 1993. Cross-linking of HLA class II antigens modulates the release of TNF-α by the EBV-B lymphoblastoid cell line JY. J. Immunol. 151:5115.
24. + B cells by clonal T cells and antigen. Proc. Natl. Acad. Sci. USA 83:7410.
25. Baluyut, A. R., and B. Subbarao. 1988. The synergistic effects of anti-IgM and monoclonal anti-1a antibodies in induction of murine B lymphocyte activation. J. Mol. Cell. Immunol. 4:45.
26. Cambier, J. C., and K. R. Lehmann. 1989. Ia-mediated signal transduction leads to proliferation of primed B lymphocytes. J. Exp. Med. 170:877.
27. Bishop, G. A., W. D. Warren, and M. T. Berton. 1995. Signaling via MHC class 11 molecules and antigen receptors enhances the B cell response to gp39/CD40 ligand. Eur. J. Immunol. 25:1230.
28. Cambier, J. C., D. C. Morrison, M. M. Chien, and K. R. Lehmann. 1991. Modeling of T cell contact-dependent B cell activation. IL-4 and antigen receptor ligation primes quiescent B cells to mobilize calcium in response to Ia cross-linking. J. Immunol. 146:2075.
29. Lane, P. J. L., F. M. McConnell, G. L. Schieven, E. A. Clark, and J. A. Ledbetter. 1990. The role of class II molecules in human B cell activation: association with phosphatidyl inositol turnover, protein tyrosine phosphorylation, and proliferation. J. Immunol. 144:3684.
30. Cambier, J. C., M. K. Newell, L. B. Justement, J. C. McGuire, K. L. Leach, and Z. Z. Chen. 1987. Ia binding ligands and cAMP stimulate nuclear translocation of PKC in B lymphocytes. Nature 327:629.
31. Bishop, G. A. 1991. Requirements of class II-mediated B cell differentiation for class II cross-linking and cAMP. J. Immunol. 147:1107.
32. Bishop, G. A., L. M. Ramirez, and T. J. Waldschmidt. 1994. Differential responses to Ig and class II-mediated signals in splenic B cell subsets from normal and autoimmune mice. Int. Immunol. 6:1049.
33. Heath, A. W., W. W. Wu, and M. C. Howard. 1994. Monoclonal Abs to murine CD40 define two distinct functional epitopes. Eur. J. Immunol. 24:1828.
34. Yoshino, T., L. Cao, R. Nishiuchi, Y. Matsuo, I. Yamadori, E. Kondo, N. Teramoto, K. Hayashi, K. Takahashi, N. Kamikawaji, and T. Akagi. 1995. Ligation of HLA class II molecules promotes sensitivity to CD95-mediated apoptosis. Ear. J. Immunol. 25:2190.
35. Hostager, B. S., Y. Hsing, D. E. Harms, and G. A. Bishop. 1996. Different CD40-mediated signaling events require distinct CD40 structural features. J. Immunol. 157:1047.
36. Palacios, R., O. Maza-Martinez, and K. Guy. 1983. Monoclonal antibodies against HLA-DR antigens replace T helper cells in activation of B lymphocytes. Proc. Natl. Acad. Sci. USA 80:3456.
37. Brick-Ghannam, C., F. L. Huang, N. Temime, and D. Charron. 1991. PKC activation via human leukocyte antigen class II molecules. J. Biol. Chem. 266:24169.
38. Mooney, N., D. Van Alewyk, C. Brick-Ghannan, and D. Charron. 1991. HLA class II antigen-mediated induction of a proliferative response to anti-IgM in human B lymphocytes. Int. J. Cancer 6:30.
39. Kansas, G. S., J. C. Cambier, and T. F. Tedder. 1992. CD4 binding to MHC class II antigens induced LFA-1-dependent and independent homotypic adhesion of B lymphocytes. Eur. J. Immunol. 22:147.
40. 2 and IFN-γ. J. Immunol. 148:3943.
41. Kubota, E., D. T. McKenzie, R. W. Dutton, and S. L. Swain. 1991. Role of T cells in the B-cell response: glutaraldehyde-fixed T-helper hybridoma cells synergize with the lymphokine IL-4 to induce B-cell activation and proliferation. Immunology 72:40.
42. Mehindate, K., R. Al-Daccak, F. Damdoumi, and W. Mourad. 1996. Synergistic effect between CD40 and class II signals overcomes the requirement for class II dimerization in superantigen-induced cytokine gene expression. Eur. J. Immunol. 26:2075.
43. Poudrier, J., and T. Owens. 1994. CD54/ICAM-1 and MHC class II signaling induces B cells to express IL-2 receptors and complements help provided through CD40 ligation. J. Exp. Med. 179:1417.
44. Jacobson. B. A., D. J. Panka, K. A. Nguyen, J. Erikson, A. K. Abbas, and A. Marshak-Rothstein. 1995. Anatomy of autoantibody production: dominant localization of antibody-producing cells to T cell zones in Fas-deficient mice. Immunity 3:509.
45. Thorley-Lawson, D. A., E. M. Miyashita, and G. Khan. 1996. EBV and the B cell: that's all it takes. Trends Microbiol. 4:204.
46. Truman, J.-P., M. L. Ericson, C. J. M. Choqueux-Seabold, D. J. Charron, and N. A. Mooney. 1994. Lymphocyte programmed cell death is mediated via HLA class II DR. Int. Immunol. 6:887.
47. Newell, M. K., J. VanderWall, K. S. Beard, and J. H. Freed. 1993. Ligation of MHC class II molecules mediates apoptotic cell death in resting B lymphocytes. Proc. Natl. Acad. Sci. USA 90:10459.
48. Wang, J., A. A. Lobito, F. Shen, F. Hornung, A. Winoto, and M. J. Lenardo. 2000. Inhibition of Fas-mediated apoptosis by the B cell antigen receptor through c-FLIP. Eur. J. Immunol. 30:155.
49. Lee, H. H., H. Dadgostar, Q. Cheng, J. Shu, and G. Cheng. 1999. NF-κB-mediated up-regulation of BCL-x and Bfl-I/A1 is required for CD40 survival signaling in B lymphocytes. Proc. Natl. Acad. Sci. USA 96:9136.
50. Wang, C., M. W. Mayo, R. G. Korneluk, D. V. Goeddel, and A. S. Baldwin. 1998. NF-κB antiapoptosis: induction of TRAF1 and TRAF2 and cIAP1 and cIAP2 to suppress caspase-8 activation. Science 281:1680.
51. Deverauz, Q. L., R. Takahashi, G. S. Salvesen, and J. C. Reed. 1997. X-linked IAP is a direct inhibitor of cell-death proteases. Nature 388:300.
52. del Peso, L., M. Gonzalez-Garcia, C. Page, R. Herrera, and G. Nuñez. 1997. IL-3-induced phosphorylation of Bad through the protein kinase Akt. Science 278:687.
53. Cardone, M. H., N. Roy, H. R. Stennicke, G. S. Salvesen, T. F. Franke, E. Stanbridge, S. Frisch, and J. C. Reed. 1998. Regulation of cell death protease caspase-9 by phosphorylation. Science 282:1318.
54. Huby, R. D., R. J. Dearman, and I. Kimber. 1999. Intracellular phosphotyrosine induction by MHC class II requires co-aggregation with membrane rafts. J. Biol. Chem. 274:22591.
55. Hostager, B. S., I. M. Catlett, and G. A. Bishop. 2000. Recruitment of CD40, TRAF2 and TRAF3 to membrane microdomains during CD40 signaling. J. Biol. Chem. 275:15392.