Endothelial dysfunction, nitric oxide and platelet activation in hypertensive and diabetic type II patients

Thrombosis Research

Volumn 102, Issue 2, 2001, Pages 107-114

  Ouvia, Susana M ^a,b   La Greca, Rodolfo D ^b   Zanaro, Noemí L ^a   Palmer, Luis ^b   Sassetti, Beatriz ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b Churruca Visca Hospital   (Argentina)

Author keywords

Diabetes; Endothelial dysfunction; Hypertension; Nitric oxide; Platelet activation; von Willebrand factor

Indexed keywords

ARGININE; ENDOTHELIN 1; GLYCOSYLATED HEMOGLOBIN; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PADGEM PROTEIN; TUMOR NECROSIS FACTOR ALPHA; VON WILLEBRAND FACTOR;

ADULT; AGED; ARTICLE; BIOAVAILABILITY; BLOOD PRESSURE; BODY MASS; CONTROLLED STUDY; DIET; DISEASE MARKER; ENDOTHELIUM LESION; ENZYME ACTIVATION; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; HYPERTENSION; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INSULINEMIA; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; THROMBOCYTE ACTIVATION; VASODILATATION;

AGED; BLOOD PRESSURE; CASE-CONTROL STUDIES; DIABETES MELLITUS, TYPE 2; ENDOTHELIUM, VASCULAR; FEMALE; HUMANS; HYPERTENSION; MALE; MIDDLE AGED; NITRIC OXIDE; PLATELET ACTIVATION; THROMBOPHILIA; TUMOR NECROSIS FACTOR-ALPHA; VON WILLEBRAND FACTOR;

EID: 0035871024     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0049-3848(01)00237-7     Document Type: Article

References (35)

1. Endothelial cells in physiology and in the pathophysiology of vascular disorders
2. Vascular endothelial dysfunction
3. The L-arginine-nitric oxide pathway
4. Serum nitrate concentration in patients with peripheral arterial occlusive disease
5. Nitrite plasma levels in type 1 and 2 diabetes with and without complications
6. Endothelial dysfunction: Does it matter? Is it reversible?
7. Endothelial dysfunction in hypertension
8. The pathogenesis of vascular complications of diabetes mellitus: One voice or many?
9. Cellular receptors for AGEs: Implications for induction of oxidant stress and cellular dysfunction in the pathogenesis on vascular lesions
10. Essential hypertension: An insulin resistence state
11. Insulin resistance in essential hypertension
12. Insulin resistance: A multifacetic syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease
13. Adverse endothelial function and the insulin resistance syndrome
14. Platelets in diabetes: The role in the hemostatic regulation in atherosclerosis
15. GMP-140: A receptor for neutrophils and monocytes on activated platelets and endothelium
16. The Molecular basis of platelet and endothelial cell interaction with neutrophils and monocytes: Role of P-selectin and the P-selectin ligand PSGL-1
17. The origin of P-selectin as a circulating plasma protein
18. Soluble P-selectin in atherosclerosis: A comparison with endothelial cell and platelet markers
19. Von Willebrand factor: A marker of endothelial dysfunction in vascular disorders?
20. Cytokine regulation of enthotelial cell function
21. The sixth report of the Joint National Commmittee on Detection, Evaluation and Treatment of High Pressure (JNC VI)
22. Nitrite and nitrate determination in plasma: A critical evaluation
23. Platelet activation by thrombine can be directely measured in whole blood through the use of peptide GPRP and flow cytometry: Methods and clinical applications
24. Advanced protein glycosylation in diabetes and aging
25. Advanced glycosylation products quench nitric oxide and mediate defective endothelium-dependent vasodilation in experimental diabetes
26. Primary hypertension: Pathogenesis
27. Contrasting autonomic and hemodinamic effects of insulin in healthy elderly versus young subjects
28. Insulin action is associated with endothelial function in hypertension and type 2 diabetes
29. Regulation of vascular homeostasis by nitric oxide
30. Nitric oxide in the pathogenesis of vascular disease
31. Higher level of plasma nitric oxide in spontaneously hypertensive rats
32. Alterations to the nitric oxide pathway in the spontaneously hypertensive rat
33. Nitric oxide: Mediator, murderer and medicine
34. Interaction between NO and reactive oxygen species: Pathophysiological importance in atherosclerosis, hypertension, diabetes and heart failure
35. Highly glycated oxyhaemoglobin impairs nitric oxide relaxations in human mesenteric microvessels