The pathogenesis of vascular complications of diabetes mellitus: One voice or many?

European Journal of Clinical Investigation

Volumn 26, Issue 7, 1996, Pages 535-543

  Stehouwer, C D A ^a,c   Schaper, N C ^b  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

^b MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^c VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Atherosclerosis; diabetes; microangiopathy; review; vascular complications

Indexed keywords

ATHEROSCLEROSIS; BLOOD VESSEL PERMEABILITY; CATION TRANSPORT; DIABETES MELLITUS; DIABETIC ANGIOPATHY; DIABETIC NEPHROPATHY; DIABETIC NEUROPATHY; DIABETIC RETINOPATHY; GLYCATION; HEMODYNAMICS; HYPERGLYCEMIA; HYPERTENSION; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RESISTANCE; MICROANGIOPATHY; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; PROTEINURIA; REVIEW; VASCULAR ENDOTHELIUM;

EID: 0029784920     PISSN: 00142972     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2362.1996.1780527.x     Document Type: Review

References (51)

1. Parving HH, Viberti GC, Keen H, Christiansen JS, Lassen NA. Haemodynamic factors in the genesis of diabetic microangiopathy. Metabolism 1983;32:943-9.
2. Tooke JE. Microvascular function in human diabetes. A physiological perspective. Diabetes 1995;44:721-6.
3. Jaap AJ, Tooke JE. Pathophysiology of microvascular disease in non-insulin-dependent diabetes mellitus. Clin Sci 1995;89:3-12.
4. Kohner EM, Patel V, Rassam SMB. Role of blood flow and impaired autoregulation in the pathogenesis of diabetic retinopathy. Diabetes 1995;44:603-7.
5. Sandeman DD, Shore AC, Tooke JE. Relation of skin capillary pressure in patients with insulin-dependent diabetes mellitus to complications and metabolic control. N Engl J Med 1992;327:760-4.
6. Patel V, Rassam S, Newsom R, Wiek J, Kohner E. Retinal blood flow in diabetic retinopathy. Br Med J 1992;305:678-83.
7. Vora JP, Anderson S, Brenner BM. Pathogenesis of diabetic glomerulopathy: the role of glomerular haemodynamic factors. In: Mogensen CE, ed. The Kidney and Hypertension in Diabetes,2nd edn.. Boston: Kluwer, 1994: 223-32.
8. Tesfaye S, Malik R, Ward JD. Vascular factors in diabetic neuropathy. Diabetologia 1994;37:847-54.
9. Williamson JR, Chang K, Allison W, Kilo C. Endoneurial blood flow changes in diabetic rats. Diabetic Med 1993;10 (Suppl. 2):49S-51S.
10. Cameron NE, Cotter MA. Potential therapeutic approaches to the treatment or prevention of diabetic neuropathy: evidence from experimental studies. Diabetic Med 1993;10:593-605.
11. Stevens EJ, Carrington AL, Tomlinson DR. Nerve ischaemia in diabetic rats: time-course of development, effect of insulin treatment plus comparison of streptozotocin and BB models. Diabetologia 1994;37:43-8.
12. Cameron NE, Cotter MA, Dines KC, Maxfield EK, Carey F, Mirrlees DJ. Aldose reductase inhibition, nerve perfusion, oxygenation and function in streptozotocin-diabetic rats: dose response considerations and independence from a myo-inositol mechanism. Diabetologia 1994;37:651-63.
13. Shore AC, Jaap AJ, Tooke JE. Capillary pressure in patients with non-insulin-dependent diabetes mellitus. Diabetes 1994;43:1198-202.
14. Trevisan R, Viberti GC. Sodium hydrogen antiport, cell function and susceptibility to diabetic nephropathy. In: Mogensen CE, ed. The Kidney and Hypertension in Diabetes, 2nd edn. Boston: Kluwer, 1994: 181-9.
15. Jensen T. Albuminuria a marker of renal and generalized vascular disease in insulin-dependent diabetes mellitus. Danish Med Bull 1991;38:134-44.
16. Gall MA, Rossing P, Skott P et al. Prevalence of micro- and macroalbuminuria, arterial hypertension, retinopathy and large vessel disease in European type 2 (non-insulin-dependent) diabetic patients. Diabetologia 1991;34:655-61.
17. Microalbuminuria Collaborative Study Group, United Kingdom. Risk factors for development of microalbuminuria in insulin-dependent diabetic patients: a cohort study. Br Med J 1993;306:1235-9.
18. Poulsen PL, Hansen KW, Mogensen CE. Ambulatory blood pressure in the transition from normo- to microalbuminuria. A longitudinal study in insulin-dependent diabetes mellitus patients. Diabetes 1994;43:1248-53.
19. Trevisan R, Nosadini R, Fioretto P et al. Clustering of risk factors in hypertensive insulin-dependent diabetics with high sodium-lithium countertransport. Kidney Int 1992;41:855-61.
20. Solini A, DeFronzo RA. Hypertension, cardiovascular disease, diabetes mellitus, and diabetic nephropathy: role of insulin resistance. In: Mogensen CE, ed. The Kidney und Hypertension in Diabetes, 2nd edn. Boston: Kluwer, 1994: 37-51.
21. DeFronzo RA, Ferranini E. Insulin resistance: A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. Diabetes Care 1991;14:173-94.
22. Elving LD, Wetzels JFM, de Pont JJHHM, Berden JHM. Is increased sodium lithium countertransport a useful marker for diabetic nephropathy? Kidney Int 1992;41:862-71.
23. Julian-Vague I, Alessi MC, Vague P. Increased plasma plasminogen activator inhibitor-1 levels. A possible link between insulin resistance and atherothrombosis. Diabetologia 1991;34:457-62.
24. Groop L, Ekstrand A, Forsblom C et al. Insulin resistance, hypertension and microalbuminuria in patients with type 2 (non-insulin-dependent) diabetes mellitus. Diabetologia 1993;36:642-7.
25. Nosadini R, Solini A, Vellusi M et al. Impaired insulin-induced glucose uptake by extrahepatic tissue is hallmark of NIDDM patients who have or will develop hypertension and microalbuminuria. Diabetes 1994;43:491-9.
26. Yip J, Mattock MB, Morocutti A, Sethi M, Trevisan R, Viberti GC. Insulin resistance in insulin-dependent diabetic patients with microalbuminuria. Lancet 1993;342:883-7.
27. Hales CN, Barker DJP. Type 2 (non-insulin-dependent) diabetes mellitus: The thrifty phenotype hypothesis. Diabetologia 1992;35:595-601.
28. Stern MP. Diabetes and cardiovascular disease. The common soil hypothesis. Diabetes 1995;44:369-74.
29. Jarrett RJ. In defence of insulin: a critique of syndrome X. Lancet 1992;340:469-71.
30. Elliott TG, Viberti GC. Relationship between insulin resistance and coronary heart disease in diabetes mellitus and the general population: a critical reappraisal. Baillière's Clin Endocrinol Metab 1993;7:1079-103.
31. Godsland IF, Stevenson JC. Insulin resistance: syndrome or tendency? Lancet 1995;346:100-3.
32. Kofoed-Enevoldsen A. The Steno hypothesis and glomerular basement membrane biochemistry in diabetic nephropathy. In: Mogensen CL, ed. The Kidney and Hypertension in Diabetes, 2nd edn. Boston: Kluwer, 1994: 203-12.
33. Myrup B, Hansen PM, Jensen T et al. Effect of low-dose heparin on urinary albumin excretion in insulin-dependent diabetes mellitus. Lancet 1995;345:421-2.
34. Lorenzi M. Glucose toxicity in the vascular complications of diabetes: The cellular perspective. Diab Metab Rev 1992;8:85-103.
35. Stehouwer CDA, Donker AJM. Urinary albumin excretion and cardiovascular disease risk in diabetes mellitus: is endothelial dysfunction the missing link? J Nephrol 1993;6:72-92.
36. Stehouwer CDA, Nauta JJP, Zeldenrust GC, Haekeng WHL, Donker AJM, den Ottolander GJH. Urinary albumin excretion, cardiovascular disease, and endothelial dysfunction in non-insulin-dependent diabetes mellitus. Lancet 1992;340:319-23.
37. Ganrot PO. Insulin resistance syndrome: possible key role of blood flow in resting muscle. Diabetologia 1993;36:876-9.
38. Steinberg HO, Brechtel G, Johnson A, Fineberg N, Baron AD. Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric oxide release. J Clin Invest 1994;94:1172-9.
39. Ader M, Bergman RN. Importance of transcapillary insulin transport to dynamics of insulin action after intravenous glucose. Am J Physiol 1994;266:E17-25.
40. Williamson JR, Chang K, Frangos M et al. Hyperglycemic pseudohypoxia and diabetic complications. Diabetes 1993;42:801-13.
41. DeRubertis FR, Craven PA. Activation of protein kinase C in glomerular cells in diabetes. Mechanisms and potential links to the pathogenesis of diabetic glomerulopathy. Diabetes 1994;43:1-8.
42. Komers R, Allen TJ, Cooper ME. Role of endothelium-derived nitric oxide in the pathogenesis of the renal hemodynamic changes of experimental diabetes. Diabetes 1994;43:1190-7.
43. Cohen RA. Dysfunction of vascular endothelium in diabetes mellitus. Circulation 1993;87 (Suppl. V):V67-V76.
44. Poston L, Taylor PD. Endothelium-mediated vascular function in insulin-dependent diabetes mellitus. Clin Sci 1995;88:245-55.
45. +)-ATPase in the slowing of nerve conduction in the streptozotocin diabetic rat. J Clin Invest 1994;94:853-9.
46. Calver A, Collier J, Vallance P. Inhibition and stimulation of nitric oxide synthesis in the human forearm arterial bed of patients with insulin-dependent diabetes. J Clin Invest 1992;90:2548-54.
47. Elliott TG, Cockcroft JR, Groop PH, Viberti GC, Ritter JM. Inhibition of nitric oxide synthesis in forearm vasculature of insulin-dependent diabetic patients: blunted vasoconstriction in patients with microalbuminuria. Clin Sci 1993;83:687-93.
48. Houben AJHM, Schaper NC, de Haan CHA et al. Local hyperglycemia for 24 h does not affect endothelium- (in)dependent vasoreactivity in men. Am J Physiol 1996 (in press).
49. Brownlee M. Glycation and diabetic complications. Diabetes 1994;43:836-41.
50. Schmidt AM, Hori O, Brett J, Yan SD, Wautier JL, Stern D. Cellular receptors for advanced glycation end products. Implications for induction of oxidant stress and cellular dysfunction in the pathogenesis of vascular lesions. Arterioscler Thromb Vasc Biol 1994;14:1521-8.
51. Fu MX, Wells-Knecht KJ, Blackledge JA, Lyons TJ, Thorpe SR, Baynes JW. Glycation, glycoxidation, and cross-linking of collagen by glucose. Kinetics, mechanisms, and inhibition of late stages of the Maillard reaction. Diabetes 1994;43:676-83.