Reeler: New tales on an old mutant mouse

BioEssays

Volumn 20, Issue 3, 1998, Pages 235-244

  D'Arcangelo, Gabriella ^a   Curran, Tom ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0032031914     PISSN: 02659247     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-1878(199803)20:3<235::AID-BIES7>3.0.CO;2-Q     Document Type: Review

References (69)

1. Sidman RL, Green MC, Appel SH (1965) Catalog of the Neurological Mutants of the Mouse. Boston: Harvard University Press.
2. Falconer DS (1951) Two new mutants "trembler" and "reeler," with neurological actions in the house mouse. J Genet 50:192-201.
3. Hamburgh M (1960) Observations on the neuropathology of "reeler," a neurological mutation in mice. Experientia 16:460-461.
4. Guenet J-L (1961) A new allele of reeler. Mouse Newsl 41:.
5. Miao GG, Smeyne RJ, D'Arcangelo G, Copeland NG, Jenkins NA, Morgan JI, Curran T (1994) Isolation of an allele of reeler by insertional mutagenesis. Proc Natl Acad Sci USA 91:11050-11054.
6. Flaherty L, Messer A, Russell LB, Rinchik EM (1992) Chlorambucil-induced mutations in mice recovered in homozygotes. Proc Natl Acad Sci USA 89:2859-2863.
7. Mariani J, Crepel F, Mikoshiba K, Changeux JP, Sotelo C (1977) Anatomical, physiological and biochemical studies of the cerebellum from Reeler mutant mouse. Philos Trans R Soc Lond Biol 281:1-28.
8. Caviness VS Jr, Rakic P (1978) Mechanisms of cortical development: A view from mutations in mice. Annu Rev Neurosci 1:297-326.
9. Goffinet AM (1984) Events governing organization of postmigratory neurons: Studies on brain development in normal and reeler mice. Brain Res 319:261-296.
10. Caviness VSJ, Crandall JE, Edwards MA (1988) The reeler Malformation. Implications for Neocortical Histogenesis. New York: Plenum Press.
11. Terashima T (1996) Distribution of mesencephalic trigeminal nucleus neurons in the reeler mutant mouse. Anat Rec 244:563-571.
12. Bliss TV, Chung SH (1974) An electrophysiological study of the hippocampus of the "reeler" mutant mouse. Nature 252:153-155.
13. Caviness VS Jr (1976) Patterns of cell and fiber distribution in the neocortex of the reeler mutant mouse. J Comp Neurol 170:435-447.
14. Steindler DA, Colwell SA (1976) Reeler mutant mouse: Maintenance of appropriate and reciprocal connections in the cerebral cortex and thalamus. Brain Res 113:386-393.
15. Watanabe M, Nakagawa S, Takayama C, Nagashima M, Inoue K, Ichikawa R, Mishina M, Inoue Y (1995) Cerebellum of the adult reeler mutant mouse contains two Purkinje cell populations with respect to gene expression for the N-methyl-D-aspartate receptor channel. Neurosci Res 22:335-345.
16. Rakic P (1971) Guidance of neurons migrating to the fetal monkey neocortex. Brain Res 33:471-476.
17. Derer P (1979) Evidence for the occurrence of early modifications in the "glia limitans" layer of the neocortex of the reeler mouse. Neurosci Lett 13:195-202.
18. Goffinet AM, Dernoncourt C (1991) Localization of the reeler gene relative to flanking loci on mouse chromosome 5. Mamm Genome 1:100-103.
19. Montgomery JC, Guarnieri MH, Tartaglia KE, Flaherty LA (1994) High-resolution genetic map and YAC contig around the mouse neurological locus reeler. Mamm Genome 5:756-761.
20. Beckers MC, Bar I, Huynh-Thu T, Dernoncourt C, Brunialti AL, Montagutelli X, Guenet JL, Goffinet AM (1994) A high-resolution genetic map of mouse chromosome 5 encompassing the reeler (rl) locus. Genomics 23:685-690.
21. Bar I, Lambert De Rouvroit C, Royaux I, Krizman DB, Dernoncourt C, Ruelle D, Beckers MC, Goffinet AM (1995) A YAC contig containing the reeler locus with preliminary characterization of candidate gene fragments. Genomics 26:543-549.
22. Buckler AJ, Chang DD, Graw SL, Brook JD, Haber DA, Sharp PA, Housman DE (1991) Exon amplification: A strategy to isolate mammalian genes based on RNA splicing. Proc Natl Acad Sci USA 88:4005-4009.
23. D'Arcangelo G, Miao GG, Chen SC, Soares HD, Morgan JI, Curran T (1995) A protein related to extracellular matrix proteins deleted in the mouse mutant reeler [see comments]. Nature 374:719-723.
24. Miao GG, D'Arcangelo G, Curran T (1995) Transgenic serendipity. A short cut to the mouse reeler gene. J NIH Res 7:51.
25. Goffinet AM (1995) A real gene for reeler. Nature 374:675-676.
26. Rakic P, Caviness VS Jr (1995) Cortical development: View from neurological mutants two decades later. Neuron 14:1101-1104.
27. Rugarli EI, Ballabio A (1995) Reelin: A novel extracellular matrix protein involved in brain lamination. BioEssays 17:832-834.
28. Royaux I, Lambert de Rouvroit C, D'Arcangelo G, Demirov D, Goffinet AM (1997) Genomic organization of the mouse reelin gene. Genomics 46:240-250.
29. Hirotsune S, Takahara T, Sasaki N, Hirose K, Yoshiki A, Ohashi T, Kusakabe M, Murakami Y, Muramatsu M, Watanabe S, et al. (1995) The reeler gene encodes a protein with an EGF-like motif expressed by pioneer neurons. Nature Genet 10:77-83.
30. Schiffmann SN, Bernier B, Goffinet AM (1997) Reelin mRNA expression during mouse brain development. Eur J Neurosci 9:1055-1071.
31. D'Arcangelo G, Miao GG, Curran T (1996) Detection of the reelin breakpoint in reeler mice. Mol Brain Res 39:234-236.
32. Takahara T, Ohsumi T, Kuromitsu J, Shibata K, Sasaki N, Okazaki Y, Shibata H, Sato S, Yoshiki A, Kusakabe M, Muramatsu M, Ueki M, Okuda K, Hayashizaki Y (1996) Dysfunction of the Orleans reeler gene arising from exon skipping due to transposition of a full-length copy of an active L1 sequence into the skipped exon. Hum Mol Genet 5:989-993.
33. Alb2, an allele of reeler isolated from a chlorambucil screen, is due to an IAP insertion with exon skipping. Genomics 42:479-482.
34. Klar A, Baldassare M, Jessel TM (1992) F-spondin: A gene expressed at high levels in the floor plate encodes a secreted protein that promotes neural cell adhesion and neurite extension. Cell 69:95-110.
35. D'Arcangelo G, Nakajima K, Miyata T, Ogawa M, Mikoshiba K, Curran T (1997) Reelin is a secreted glycoprotein recognized by the CR-50 monoclonal antibody. J Neurosci 17:23-31.
36. Ogawa M, Miyata T, Nakajima K, Yagyu K, Seiko M, Ikenaka K, Yamamoto H, Mikoshiba K (1995) The reeler gene-associated antigen on Cajal-Retzius neurons is a crucial molecule for laminar organization of cortical neurons. Neuron 14:899-912.
37. Miyata T, Nakajima K, Mikoshiba K, Ogawa M (1997) Regulation of Purkinje cell alignment by Reelin as revealed with CR-50 antibody. J Neurosci 17:3599-3609.
38. Del Rio JA, Heimrich B, Borrell V, Forster E, Drakew A, Alcantara S, Nakajima K, Miyata T, Ogawa M, Mikoshiba K, Derer P, Frotscher M, Soriano E (1997) A role for Cajal-Retzius cells and reelin in the development of hippocampal connections. Nature 385:70-74.
39. Nakajima K, Mikoshiba K, Miyata T, Kudo C, Ogawa M (1997) Disruption of hippocampal development in vivo by CR-50 mAb against Reelin. Proc Natl Acad Sci USA 94:8196-8201.
40. rl-Orl). Mol Brain Res 50:85-90.
41. Marin-Padilla M (1978) Dual origin of the mammalian neocortex and evolution of the cortical plate. Anat Embryol (Berl) 152:109-126.
42. Angevine JG, Sidman RL (1961) Autoradiographic study of cell migration during histogenesis of cerebral cortex in the mouse. Nature 192:766-768.
43. 3H]thymidine autoradiography. Brain Res 256:293-302.
44. Pinto-Lord MC, Evrard P, Caviness VSJ (1982) Obstructed neuronal migration along radial glial fibers in the neocortex of the reeler mouse: A Golgi-EM analysis. Dev Brain Res 4:379-393.
45. Yuasa S, Kitoh J, Oda S, Kawamura K (1993) Obstructed migration of Purkinje cells in the developing cerebellum of the reeler mutant mouse. Anat Embryol (Berl) 188:317-329.
46. Anton ES, Matthew WD, Rakic P (1996) A regionally distributed radial glia antigen: A candidate for signaling an end to neuronal migration. Soc Neurosci Abs 22:1206.
47. Hoffarth RM, Johnston JG, Krushel LA, van der Kooy D (1995) The mouse mutation reeler causes increased adhesion within a subpopulation of early postmitotic cortical neurons. J Neurosci 15:4838-4850.
48. Sheppard AM, Pearlman AL (1997) Abnormal reorganization of preplate neurons and their associated extracellular matrix: An early manifestation of altered neocortical development in the reeler mutant mouse. J Comp Neurol 378:173-179.
49. DeLong GR, Sidman RL (1970) Alignment defect of reaggregating cells in cultures of developing brains of reeler mutant mice. Dev Biol 563:584-600.
50. Rakic P (1971) Neuron-glia relationship during granule cell migration in developing cerebellar cortex. J Comp Neurol 141:283-312.
51. Miyata T, Nakajima K, Aruga J, Takahashi S, Ikenaka K, Mikoshiba K, Ogawa M (1996) Distribution of the reeler gene-related antigen in the developing cerebellum: An immunohistochemical study with an allogenic antibody CR-50 on normal and reeler mice. J Comp Neurol 372:215-228.
52. Goffinet AM (1983) The embryonic development of the cerebellum in normal and reeler mutant mice. Anat Embryol (Berl) 168:73-86.
53. Green-Johnson JM, Zalcman S, Vriend CY, Nance DM, Greenberg AH (1995) Suppressed T cell and macrophage function in the "reeler" (rl/rl) mutant, a murine strain with elevated cerebellar norepinephrine concentration. Brain Behav Immun. 9:47-60.
54. Culotti JG, Kolodkin AL (1996) Functions of netrins and semaphorins in axon guidance. Curr Opin Neurobiol 6:81-88.
55. Sweet HO, Bronson RT, Johnson KR, Cook SA, Davisson MT (1996) Scrambler, a new neurological mutation of the mouse with abnormalities of neuronal migration. Mamm Genome 7:798-802.
56. Yoneshima H, Nagata E, Matsumoto M, Yamada M, Nakajima K, Miyata T, Ogawa M, Mikoshiba K (1997) A novel neurological mutation of mouse, yotari, which exhibits reeler-like phenotype but expresses reelin. Neurosci Res 29:217-223.
57. Goldowitz D, Cushing RC, Laywell E, D'Arcangelo G, Sheldon M, Sweet HO, Davisson M, Steindler D, Curran T (1997) Cerebellar disorganization characteristic of reeler in scrambler mutant mice despite presence of Reelin. J Neurosci 17:8767-8777.
58. Gonzalez JL, Goldowitz D, Sweet HO, Davisson MT, Walsh CA (1997) Birthdate and cell marker analysis of scrambler: A novel mutation affecting cortical development with a reeler-hke phenotype. J Neurosci 17:9204-9211.
59. Sheldon M, Rice DS, D'Arcangelo G, Yoneshima H, Nakajima K, Mikoshiba K, Howell BW, Cooper JA, Goldowitz D, Curran T Scrambler and yotari disrupt the disabled gene and produce a reeler-like phenotype in mice. Nature 389:730-733.
60. Ware ML, Fox JW, Gonzales JL, Davis NM, Lambert de Rouvroit C, Russo CJ, Chua SCJ, Goffinet AM, Walsh CA (1997) Aberrant splicing of a mouse disabled homolog, mdab1, in the scrambler mouse. Neuron 19:239-249.
61. Goffinet AM (1997) Unscrambling a disabled brain. Nature 389:668-669.
62. Howell BW, Hawkes R, Soriano P, Cooper JA (1997) Neuronal position in the developing brain is regulated by mouse disabled-1. Nature 389:733-736.
63. Howell BW, Gertler FB, Cooper JA (1997) Mouse disabled (mDab)1): A src binding protein implicated in neuronal development. EMBO J 16:121-132.
64. Xu XX, Yang W, Jackowski S, Rock CO (1995) Cloning of a novel phosphoprotein regulated by colony-stimulating factor 1 shares a domain with the Drosophila disabled gene product. J Biol Chem 270:14184-14191.
65. Gertler FB, Bennet RL, Clark MJ, Hoffmann FM (1989) Drosophila abl tyrosine kinase in embryonic CNS axons: A role in axogenesis is revealed through dosage-sensitive interactions with disabled. Cell 58:103-113.
66. Ohshima T, Ward JM, Huh CG, Longenecker G, Veeranna Pant HC, Brady RO, Martin LJ, Kulkarni AB (1996) Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death. Proc Natl Acad Sci USA 93:11173-11178.
67. Chae T, Kwon YT, Bronson R, Dikkes P, Li E, Tsai LH (1997) Mice lacking p35, a neuronal specific activator of Cdk5, display cortical lamination defects, seizures, and adult lethality. Neuron 18:29-42.
68. DeSilva U, D'Arcangelo G, Braden VV, Chen J, Miao G, Curran T, Green ED (1997) The human reelin gene: Isolation, sequencing, and mapping on chromosome 7. Genome Res 7:157-164.
69. Best LG, Wasdahl WA, Larson LM, Sturlaugson J (1990) Chromosome abnormality in Kallmann syndrome. Am J Med Genet 35:306-309.