The antibiotic microcin B17 is a DNA gyrase poison: Characterisation of the mode of inhibition

Journal of Molecular Biology

Volumn 307, Issue 5, 2001, Pages 1223-1234

  Heddle, Jonathan G ^a,b   Blance, Stephen J ^a   Zamble, Deborah B ^c   Hollfelder, Florian ^c   Miller, Deborah A ^c   Wentzell, Lois M ^a   Walsh, Christopher T ^c   Maxwell, Anthony ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b JOHN INNES CENTRE   (United Kingdom)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

CcdB; Gyrase inhibitor; Quinolone; Supercoiling; Topoisomerase

Indexed keywords

ADENOSINE TRIPHOSPHATE; ADENYLYLIMIDODIPHOSPHATE; BACTERIAL TOXIN; BACTERIAL TOXIN CCDB; CALCIUM ION; CIPROFLOXACIN; DNA TOPOISOMERASE (ATP HYDROLYSING); GYRASE INHIBITOR; MICROCIN B17; QUINOLONE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERICIDAL ACTIVITY; CALCIUM TRANSPORT; CONTROLLED STUDY; CROSS RESISTANCE; DNA SUPERCOILING; ENZYME BINDING; ENZYME INHIBITOR INTERACTION; ENZYME SYNTHESIS; MOLECULAR STABILITY; NONHUMAN; PRIORITY JOURNAL;

BACTERIA (MICROORGANISMS);

EID: 0035853284     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2001.4562     Document Type: Article

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