Four loops of the catalytic domain of factor VIIa mediate the effect of the first EGF-like domain substitution on factor VIIa catalytic activity

Journal of Molecular Biology

Volumn 307, Issue 5, 2001, Pages 1503-1517

  Jin, Jianping ^a   Perera, Lalith ^b   Stafford, Darrel ^a   Pedersen, Lee ^b,c  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b University of North Carolina at Chapel Hill   (United States)

^c NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Blood coagulation factor; Domain substitution; Macromolecular simulation; Structure function study; Tissue factor

Indexed keywords

BLOOD CLOTTING FACTOR 7A; BLOOD CLOTTING FACTOR 8; CALCIUM ION; CHYMOTRYPSIN; EPIDERMAL GROWTH FACTOR; THROMBOPLASTIN;

ARTICLE; BINDING AFFINITY; BLOOD CLOTTING; CATALYSIS; ENZYME ACTIVE SITE; ENZYME ACTIVITY; PRIORITY JOURNAL; PROTEIN DOMAIN;

EID: 0035853273     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2001.4556     Document Type: Article

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