Assessment of the role of an ω loop of cholesterol oxidase: A truncated loop mutant has altered substrate specificity

Biochemistry

Volumn 37, Issue 16, 1998, Pages 5770-5778

  Sampson, Nicole S ^a   Kass, Ignatius J ^a   Ghoshroy, Kajal Bose ^a,b  

^a STONY BROOK UNIVERSITY   (United States)

^b MISSISSIPPI UNIVERSITY FOR WOMEN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL OXIDASE; MUTANT PROTEIN;

ARTICLE; BINDING AFFINITY; CIRCULAR DICHROISM; CRYSTAL STRUCTURE; ENZYME ANALYSIS; ENZYME BINDING; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; MEMBRANE BINDING; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; BINDING SITES; BREVIBACTERIUM; CATALYSIS; CHOLESTEROL OXIDASE; CRYSTALLOGRAPHY, X-RAY; DEUTERIUM; ENZYME ACTIVATION; LIPID BILAYERS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, INSERTIONAL; PROTEIN STRUCTURE, SECONDARY; STREPTOMYCES; SUBSTRATE SPECIFICITY;

EID: 0032554645     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi973067g     Document Type: Article

References (50)

1. Kempner, E. S. (1993) FEBS Lett. 326, 4-10.
2. Fetrow, J. S. (1995) FASEB J. 9, 708-717.
3. Leszczynski, J. F., and Rose, G. D. (1986) Science 234, 849-855.
4. Koshland, D. E., Jr. (1958) Proc. Natl. Acad. Sci. U.S.A. 44, 98-104.
5. Herschlag, D. (1988) Bioorg. Chem. 16, 62-96.
6. Clarke, A. R., Wigley, D. B., Chia, W. N., Barstow, D., Atkinson, T., and Holbrook, J. J. (1986) Nature (London) 324, 699-702.
7. First, E. A., and Fersht, A. R. (1993) Biochemistry 32, 13658-13663.
8. Li, L., Falzone, C. J., Wright, P. E., and Benkovic, S. J. (1992) Biochemistry 31, 7826-7833.
9. Kato, H., Tanaka, T., Yamaguchi, H., Hara, T., Nishioka, T., Katsube, Y., and Oda, J. (1994) Biochemistry 33, 4995-4999.
10. Pompliano, D. L., Peyman, A., and Knowles, J. R. (1990) Biochemistry 29, 3186-3194.
11. Larson, E. M., Larimer, F. W., and Hartman, F. C. (1995) Biochemistry 34, 4531-4537.
12. Fetrow, J. S., Horner, S. R., Oehrl, W., Schaak, D. L., Boose, T. L., and Burton, R. E. (1997) Protein Sci. 6, 197-210.
13. Pullybank-Mulligan, P., Spitzer, J. S., Gilden, B. M., and Fetrow, J. S. (1996) J. Biol. Chem. 271, 8633-8645.
14. Yang, X.-J., and Miles, W. W. (1992) J. Biol. Chem. 267, 7520-7528.
15. Carrière, F., Thirstrup, K., Hjorth, S., Ferrato, F., Nielsen, P. F., Withers-Martinez, C., Cambillau, C., Boel, E., Thim, L., and Verger, R. (1997) Biochemistry 36, 239-248.
16. Egloff, M.-P., Marguet, F., Buono, G., Verger, R., Cambillau, C., and Tilbeurgh, H. V. (1995) Biochemistry 34, 2751-2762.
17. Derewenda, U., Brzozowski, A. M., Lawson, D. M., and Derewenda, Z. S. (1992) Biochemistry 31, 1532-1541.
18. Li, J., Vrielink, A., Brick, P., and Blow, D. M. (1993) Biochemistry 32, 11507-11515.
19. Vrielink, A., Lloyd, L. F., and Blow, D. M. (1991) J. Mol. Biol. 219, 533-554.
20. Ishizaki, T., Hirayama, N., Shinkawa, H., Nimi, O., and Murooka, Y. (1989) J. Bacteriol. 171, 596-601.
21. Ohta, T., Fujishiro, K., Yamaguchi, K., Tamura, Y., Aisaka, K., Uwajima, T., and Hasegawa, M. (1991) Gene 103, 93-96.
22. Nomura, N., Choi, K.-P., and Murooka, Y. (1995) J. Ferm. Bioeng. 79, 410-416.
23. Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989) Molecular cloning: a laboratory manual, 2nd ed., Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York.
24. Sanger, F., Niklen, S., and Coulson, A. R. (1977) Proc. Natl. Acad. Sci. U.S.A. 74, 5463-5467.
25. Ghoshroy, K. B., Zhu, W., and Sampson, N. S. (1997) Biochemistry 36, 6133-6140.
26. Fasman, G. D. (1992) Practical Handbook of Biochemistry and Molecular Biology, C. R. C. Press, Boca Raton, FL.
27. Hope, M. J., Bally, M. B., Webb, G., and Cullis, P. R. (1985) Biochim. Biophys. Acta 812, 55-65.
28. Stewart, J. C. M. (1959) Anal. Biochem. 104, 10-14.
29. Smith, A. G., and Brooks, C. J. W. (1977) Biochem. J. 167, 121-129.
30. Sampson, N. S., and Kass, I. J. (1997) J. Am. Chem. Soc. 119, 855-862.
31. Kass, I. J., and Sampson, N. S. (1995) Biochem. Biophys. Res. Commun. 206, 688-693.
32. Purcell, J. P., Greenplate, J. T., Jennings, M. G., Ryerse, J. S., Pershing, J. C., Sims, S. R., Prinsen, M. J., Corbin, D. R., Tran, M., Sammons, R. D., and Stonard, R. J. (1993) Biochem. Biophys. Res. Commun. 196, 1406-1413.
33. Greenplate, J. T., Duck, N. B., Pershing, J. C., and Purcell, J. P. (1995) Entomol Exp. Appl. 74, 253-258.
34. Lange, Y. (1992) J. Lipid Res. 33, 315-321.
35. Schick, M. J., Atlas, S. M., and Eirich, F. R. (1962) J. Phys. Chem. 66, 1326-1333.
36. Haberland, M. E., and Reynolds, J. A. (1973) Proc. Natl. Acad. Sci U.S.A. 70, 2313-2316.
37. Phillips, M. C., Johnson, W. J., and Rothblat, G. H. (1987) Biochim. Biophys. Acta 906, 223-276.
38. Lund-Katz, S., Laboda, H. M., McLean, L. R., and Phillips, M. C. (1988) Biochemistry 27, 3416-3423.
39. Bar, L. K., Chong, P. L.-G., Barenholz, Y., and Thompson, T. E. (1989) Biochim. Biophys. Acta 983, 109-112.
40. Rodrigueza, W. V., Wheeler, J. J., Klimuk, S. K., Kitson, C. N., and Hope, M. J. (1995) Biochemistry 34, 6208-6217.
41. McLean, L. R., and Phillips, M. C. (1981) Biochemistry 20, 2893-2900.
42. Loubat-Hugel, C., Tritsch, D., and Biellmann, J. F. (1994) C. R. Acad. Sci., Ser. III 317, 299-303.
43. Thirstrup, K., Verger, R., and Carrière, F. (1994) Biochemistry 33, 2748-2756.
44. Bengtsson, G., and Olivecrona, T. (1981) Eur. J. Biochem. 113, 547-554.
45. Ghosh, D., Wawrzak, Z., Pletnev, V. Z., Li, N., Kaiser, R., Pangborn, W., Jornvall, H., Erman, M., and Duax, W. L. (1995) Structure 3, 279-288.
46. Scott, D. L., White, S. P., Otwinowski, Z., Yuan, W., Gelb, M. H., and Sigler, P. B. (1990) Science 250, 1541-1546.
47. van den Berg, B., Tessari, M., Boelens, R., Dijkman, R., de Haas, G. H., Kaptein, R., and Verheij, H. M. (1995) Struct. Biol. 2, 402-406.
48. Cambillau, C., Longhi, S., Nicolas, A., and Martinez, C. (1996) Curr. Opin. Struct. Biol. 6, 449-455.
49. Gerstein, M., Lesk, A. M., and Chothia, C. (1994) Biochemistry 33, 6739-6749.
50. Kraulis, P. J. (1991) J. Appl. Crystal. 24, 946-950.