Differential expression of cocaine- and amphetamine-regulated transcript and agouti related-protein in chronically food-restricted sheep

Brain Research

Volumn 918, Issue 1-2, 2001, Pages 40-50

  Henry, Belinda A ^a   Rao, Alexandra ^a   Ikenasio, Bettina A ^b   Mountjoy, Kathleen G ^b   Tilbrook, Alan J ^c   Clarke, Iain J ^a  

^a HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

^c MONASH UNIVERSITY   (Australia)

Author keywords

Bodyweight; Feeding behaviour; Melanocortin system; Nutritional status

Indexed keywords

AGOUTI RELATED PROTEIN; ALPHA INTERMEDIN; COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT; MESSENGER RNA; PROOPIOMELANOCORTIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARCUATE NUCLEUS; ARTICLE; BODY WEIGHT; BRAIN REGION; CONTROLLED STUDY; DIET RESTRICTION; FEMALE; HOMEOSTASIS; HYPOTHALAMUS; HYPOTHALAMUS NUCLEUS; IN SITU HYBRIDIZATION; LIPID STORAGE; NONHUMAN; NUTRITIONAL STATUS; OVARIECTOMY; POSTERIOR HYPOTHALAMUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SATIETY; SHEEP; THALAMUS MIDLINE NUCLEUS; TRANSCRIPTION REGULATION;

ANIMALS; ARCUATE NUCLEUS; BODY WEIGHT; EATING; FEMALE; FOOD DEPRIVATION; FOOD, FORMULATED; GENE EXPRESSION REGULATION; HOMEOSTASIS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; NERVE TISSUE PROTEINS; PRO-OPIOMELANOCORTIN; PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SHEEP;

EID: 0035834319     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(01)02918-3     Document Type: Article

References (64)

1. Short-term starvation decreases POMC mRNA but does not alter GnRH mRNA in the brain of adult male rats
2. Endogenous opioid peptides and hypothalamic neuroendocrine neurones
3. Altered expression of hypothalamic neuropeptide mRNAs in food-restricted and food-deprived rats
4. Distribution and characterization of cyclooxygenase immunoreactivity in the ovine brain
5. Hypothalamic cocaine- and amphetamine-regulated transcript (CART) neurons: Histochemical relationship to thyrotropin-releasing hormone, melanin-concentrating hormone, orexin/hypocretin and neuropeptide Y
6. A unique metabolic syndrome causes obesity in the melanocortin-3 receptor-deficient mouse
7. CART peptide immunoreactivity in the hypothalamus and pituitary in monkeys: Analysis of ultrastructural features and synaptic connections in the paraventricular nucleus
8. Topography and associations of luteinizing hormone-releasing hormone and neuropeptide Y-immunoreactive neuronal systems in the human diencephalon
9. Cocaine- and amphetamine-regulated transcript, glucagon-like peptide-1 and corticotrophin releasing factor inhibit feeding via agouti-related protein independent pathways in the rat
10. Leptin activates hypothalamic CART neurons projecting to the spinal cord
11. alpha-Melanocyte-stimulating hormone is contained in nerve terminals innervating thyrotropin-releasing hormone-synthesizing neurons in the hypothalamic paraventricular nucleus and prevents fasting-induced suppression of prothyrotropin-releasing hormone gene expression
12. ART (protein product of agouti-related transcript) as an antagonist of MC-3 and MC-4 receptors
13. Role of the CNS melanocortin system in the response to overfeeding
14. Orexin A activates locus coeruleus cell firing and increases arousal in the rat
15. Coexpression of Agrp and NPY in fasting-activated hypothalamic neurons
16. Intracerebroventricular infusion of leptin elevates the secretion of luteinising hormone without affecting food intake in long-term food-restricted sheep, but increases growth hormone irrespective of bodyweight
17. Long-term alterations in adiposity affect the expression of melanin-concentrating hormone and enkephalin but not proopiomelanocortin in the hypothalamus of ovariectomized ewes
18. Human cocaine- and amphetamine-regulated transcript (CART) mRNA is highly expressed in limbic- and sensory-related brain regions
19. Targeted disruption of the melanocortin-4 receptor results in obesity in mice
20. Localization of melanocortin receptor mRNA (MC3-R and MC-4R) in the sheep diencephalon and brainstem
21. Obesity and impaired prohormone processing associated with mutations in the human prohormone convertase 1 gene
22. The control of the gonadotrophin releasing hormone pulse generator in relation to opioid and nutritional cues
23. The regulation of body weight
24. Chronic food restriction and acute food deprivation decrease mRNA levels of opioid peptides in arcuate nucleus
25. The central melanocortin system affects the hypothalamo-pituitary thyroid axis and may mediate the effect of leptin
26. Intra-ventral tegmental area injection of rat cocaine and amphetamine-regulated transcript peptide 55-102 induces locomotor activity and promotes conditioned place preference
27. Immunohistochemical localization of novel CART peptides in rat hypothalamus, pituitary and adrenal gland
28. Hypothalamic CART is a new anorectic peptide regulated by leptin
29. Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans
30. Cocaine and amphetamine-regulated-transcript peptide mediation of leptin stimulatory effect on the rat gonadotropin-releasing hormone pulse generator in vitro
31. Do gonadotropin-releasing hormone, tyrosine hydroxylase-, and β-endorphin-immunoreactive neurons contain oestrogen receptors? A double-label immunocytochemical study in the Suffolk ewe
32. Changes in energy expenditure resulting from altered body weight
33. A critical role of the posterior hypothalamus in the mechanisms of wakefulness determined by microinjection of muscimol in freely moving cats
34. Leptin receptor, NPY, POMC mRNA expression in the diet-induced obese mouse brain
35. Hypothalamic control of photoperiod-induced cycles in food intake, body weight, and metabolic hormones in rams
36. Influence of food restriction on neuropeptide-Y, proopiomelanocortin, and luteinizing hormone-releasing hormone gene expression in sheep hypothalami
37. Defense of a lowered weight maintenance level by lateral hypothamically lesioned rats: Evidence from a restriction-refeeding regimen
38. Hypothalamic agouti-related protein messenger ribonucleic acid is inhibited by leptin and stimulated by fasting
39. Orexin-induced hyperlocomotion and stereotypy are mediated by the dopaminergic system
40. GABA release in posterior hypothalamus across sleep-wake cycle
41. Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein
42. Leptin effects on pulsatile gonadotropin releasing hormone secretion from the adult rat hypothalamus and interaction with cocaine and amphetamine regulated transcript peptide and neuropeptide Y
43. Feed restriction in prepubertal lambs: Effect on puberty onset and on in vivo release of luteinizing-hormone-releasing hormone, neuropeptide Y and beta-endorphin from the posterior-lateral median eminence
44. A C-terminal fragment of Agouti-related protein increases feeding and antagonizes the effect of alpha-melanocyte stimulating hormone in vivo
45. Melanin-concentrating hormone (MCH) antagonizes the effects of alpha-MSH and neuropeptide E-I on grooming and locomotor activities in the rat
46. Satiety effect and sympathetic activation of leptin are mediated by hypothalamic melanocortin system
47. A complete protocol for in situ hybridization of messenger RNAa in brain and other tissues with radio-labeled single-stranded RNA probes
48. Immunocytochemical identification of oestrogen receptors in the ovine pars tuberalis: Localization within gonadotrophs
49. Agouti related peptide (Agrp) stimulates the hypothalamo pituitary gonadal axis in vivo and in vitro in male rats
50. Role of hypothalamic catecholamines in the regulation of luteinizing hormone and prolactin secretion in the ewe during seasonal anestrus
51. Distribution of melanin-concentrating hormone (MCH)-like immunoreactivity in neurons of the diencephalon of sheep
52. Neuronal projections to the lateral retrochiasmatic area of sheep with special reference to catecholaminergic afferents: Immunohistochemical and retrograde tract-tracing studies
53. A frameshift mutation in human MC4R is associated with a dominant form of obesity
54. Recombinant CART peptide induces c-Fos expression in central areas involved in control of feeding behaviour
55. Microinjection of GABA antagonists into the posterior hypothalamus elicits locomotor activity and a cardiorespiratory activation
56. Effects of central administration of highly selective opioid mu-, delta- and kappa-receptor agonists on plasma luteinizing hormone (LH), prolactin, and the estrogen-induced LH surge in ovariectomized ewes
57. Blockade of the oestrogen-induced luteinizing hormone surge in ovariectomized ewes by a highly selective opioid mu-receptor agonist: Evidence for site of action
58. Proopiomelanocortin mRNA levels in ovine hypothalamus are not reduced at the time of the preovulatory luteinising hormone surge
59. Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin
60. A frameshift mutation in MC4R associated with dominantly inherited human obesity
61. Differential expression of hypothalamic neuropeptides in the early phase of diet-induced obesity in mice
62. Evidence that orexin-containing neurons provide direct input to gonadotropin releasing hormone neurons in the ovine hypothalamus
63. Effects of vasopressin and elimination of corticotropin-releasing hormone-target cells on pro-opiomelanocortin mRNA levels and adrenocorticotropin secretion in ovine anterior pituitary cells