Tumor pathogenesis of human neurotropic JC virus in the CNS

Journal of NeuroVirology

Volumn 4, Issue 2, 1998, Pages 175-181

  Gallia, Gary L ^a   Gordon, Jennifer ^a   Khalili, Kamel ^a  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Animal model; Human brain tumors; JCV; Progressive multifocal leukoencephalopathy; T antigen

Indexed keywords

VIRUS T ANTIGEN;

BRAIN TUMOR; CHOROID PLEXUS PAPILLOMA; EPENDYMOMA; HUMAN; JC VIRUS; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY; REVIEW; VIRUS CARCINOGENESIS; VIRUS CELL TRANSFORMATION;

EID: 0031980448     PISSN: 13550284     EISSN: None     Source Type: Journal    
DOI: 10.3109/13550289809114517     Document Type: Review

References (46)

1. Astrom K-E, Mancall EL, Richardson EP Jr (1958). Progressive multifocal leukoencephalopathy: a hitherto unrecognized complication of chronic lymphocytic leukemia and lymphoma. Brain 81: 93-111.
2. Berger JR, Concha M (1995). Progressive multifocal leukoencephalopathy: the evolution of a disease once considered rare. J Neurovirol 1: 5-18.
3. Bergsagel DJ, Finegold MJ, Butel JS, Kupsky WJ, Garcea RL (1992). DNA sequences similar to those of simian virus 40 in ependymomas and choroid plexus tumors of childhood. New Engl J Med 326: 988-993.
4. Boldorini R, Caldarelli-Stefano R, Monga G, Zocchi M, Mediati M, Tosoni A, Ferrante P (1998). PCR detection of JC virus DNA in the brain tissue of a 9-year-old child with pleomorphic xanthoastrocytoma. J Neurovirol 4: 242-245.
5. Brinster RL, Chen HY, Messing A, van Dyke T, Levine AJ, Palmiter RD (1984). Transgenic mice harboring SV40 T-antigen genes develop characteristic brain tumors. Cell 37: 367-379.
6. Brooks BR, Walker DL (1984). Progressive multifocal leukoencephalopathy. Neurol Clin 2: 299-333.
7. Castaigne P, Rondot P, Escourolle R, Ribadeau Dumas J-L, Cathala F, Hauw J-J (1974). Progressive multifocal leukoencephalopathy and multiple gliomas. Rev Neurol Paris 130: 379-392.
8. Davies JA, Hughs JT, Oppenheimer DR (1973). Richardson's disease (progressive multifocal leukoencephalopathy). Q J Med 167: 481-501.
9. Dirks PB, Rutka JT (1997). Current concepts in neurooncology: the cell cycle - a review. Neurosurgery 40: 1000-1013.
10. Dorries K, Loeber G, Meixensberger J (1987). Association of polyomavirus JC, SV40 and BK with human brain tumors. Virology 160: 268-270.
11. Dyson N, Bernards R, Friend SH, Gooding LR, Hassell JA, Major EO, Pipas JM, van Dyke T, Harlow E (1990). Large T antigens of many polyomaviruses are able to form complexes with the retinoblastoma protein. J Virol 64: 1353-1356.
12. Dyson N, Buchkovich K, Whyte P, Harlow E (1989). The cellular 107K protein that binds to adenovirus E1A also associates with the large T antigens of SV40 and JC virus. Cell 58: 249-255.
13. Egan JD, Ring BI, Reding MJ, Wells IC, Shuman RM (1980). Reticulum cell sarcoma and progressive multifocal leukoencephalopathy following renal transplantation. Transplantation 29: 84-86.
14. Franks RR, Rencic A, Gordon J, Zoltick, PW, Curtis M, Knobler RL, Khalili K (1996). Formation of undifferentiated mesenteric tumors in transgenic mice expressing human neurotrophic polyomavirus early protein. Oncogens 12: 2573-2578.
15. Frisque RJ, White FA III (1992). The molecular biology of JCV, causative agent of progressive multifocal leukoencephalopathy. In: RP Roos (ed). Molecular Neurovirology. Humana Press: Totowa, NJ. pp. 25-158.
16. GiaRusso MH, Koeppen AH (1978). Atypical progressive multifocal leukoencephalopathy and primary cerebral malignant lymphoma. J Neurol Sci 35: 391-398.
17. Greenlee JE, Becker LE, Narayan O, Johnson RT (1978). Failure to demonstrate papovavirus tumor antigen in human cerebral neoplasms. Ann Neurol 3: 479-481.
18. Gullotta F, Masini T, Scarlato G, Kuchelmeister K (1992). Progressive multifocal leukoencephalopathy and gliomas in a HIV-negative patient. Path Res Pract 188: 964-972.
19. Ho K-C, Garancis JC, Paegle RD, Gerber MA, Borkowski WJ (1980). Progressive multifocal leukoencephalopathy and malignant lymphoma of the brain in a patient with immunosuppressive therapy. Acta Neuropathol 52: 81-83.
20. Kosaka H, Sano Y, Matsukado Y, Sairenji T, Himuma Y (1980). Failure to detect papovavirus-associated T antigens in human brain tumor cells by anticomplement immunofluorescence. J Neurosurg 52: 367-370.
21. Krynska B, Gordon J, Otte J, Franks R, Knobler R, DeLuca A, Giordano A, Khalili K (1997). Role of cell cycle regulators in tumor formation in transgenic mice expressing the human neurotropic virus, JCV, early protein. J Cell Biochem 67: 223-230.
22. Lazutka JR, Neel JV, Major EO, Dedonyte V, Mierauskine J, Slapsyte G, Kesminiene A (1996). High titres of antibodies to two human polyomaviruses, JCV and BKV, correlate with increased frequency of chromosomal damage in human lymphocytes. Cancer Letters 109: 177-183.
23. Lednicky JA, Garcea RL, Bergsagel DJ, Butel JS (1995). Natural Simian Virus 40 strains are present in human choroid plexus and ependymoma tumors. Virology 212: 710-717.
24. Liberski PP, Alwasiak J, Wegrzyn Z (1982). Atypical progressive multifocal leukoencephalopathy and primary cerebral lymphoma. Neuropat Pol 20: 413-419.
25. London WT, Houff SA, Madden DL, Fuccillo DA, Gravell M, Wallen WC, Palmer AE, Sever JL, Padgett BL, Walker DL, ZuRhein GM, Ohashi T (1978). Brain tumors in owl monkeys inoculated with a human polyomavirus (JCV). Science 201: 1246-1249.
26. London WT, Houff SA, McKeever PE, Wallen WC, Sever JL, Padgett BL, Walker DL (1983). Viral-induced astrocytomas in squirrel monkeys. In: Polyomavaviruses and human neurological diseases. Alan R Liss Inc: New York, pp 227-237.
27. Ludlow JW (1993), Interactions between SV40 large-tumor antigen and the growth suppressor proteins pRB and p53. FASEB J 7: 866-871.
28. Major EO, Amemiya K, Tornatore CS, Houff SA, Berger JR (1992). Pathogenesis and molecular biology of progressive multifocal leukoencephalopathy, the JC virus-induced demyelinating disease of the human brain. Clin Micro Rev 5: 49-73.
29. Mandl C, Walker DL, Frisque RJ (1987). Derivation and characterization of POJ cells, transformed human fetal glial cells that retain their permissivity for JC virus. J Virol 61: 755-763.
30. Martini F, Iaccheri L, Lazzarin L, Carinic P, Corallini A, Gerosa M, Iuzzoline P, Barbanti-Brodano G, Tognon M (1996). SV40 early region and large T antigen in human brain tumors, peripheral blood cells, and sperm fluids from healthy individuals. Cancer Res 56: 4820-4825.
31. Neel JV, Major EO, Awa AA, Glover T, Burgess A, Traub R, Curfman B, Satoh C (1996). Hypothesis: 'Rogue cell'-type chromosomal damage in lymphocytes is associated with infection with the JC human polyoma virus and has implications for oncogenesis. Proc Natl Acad Sci USA 93: 2690-2695.
32. Ohsumi S, Motoi M, Ogawa K (1986). Induction of undifferentiated tumors by JC virus in the cerebrum of rats. Acta Pathol Jpn 36: 815-825.
33. Ohsumi S, Ikehara I, Motoi M, Ogawa K, Nagashima K, Yasui K (1985). Induction of undifferentiated brain tumors in rats by a human polyomavirus (JCV). Japan J Cancer Res 76: 429-431.
34. Rencic A, Gordon J, Otte J, Curtis M, Kovatich A, Zoltick P, Khahli K, Andrews D (1996). Detection of JC virus DNA sequence and expression of the viral oncoprotein, tumor antigen, in brain of immunocompetent patient with oligoastrocytoma. Proc Natl Acad Sci USA 93: 7352-7357.
35. Richardson EP Jr (1970). Progressive multifocal leukoencephalopathy. In: Vinken PJ, Bruyn GW (eds). Handbook of Clinical Neurology. Vol 9. Multiple Sclerosis and Other Demyelinating Diseases. Elsevier/North Holland: New York, pp. 486-499.
36. Richardson EP Jr (1961). Progressive multifocal leukoencephalopathy. New Engl J Med 265: 815-823.
37. Sima AAF, Finkelstein SD, McLachlan DR (1983). Multiple malignant astrocytomas in a patient with spontaneous progressive multifocal leukoencephalopathy. Ann Neurol 14: 183-188.
38. Small JA, Scangos GA, Cork L, Jay G, Khoury G (1986a). The early region of human papovavirus JC induces dysmyelination in transgenic mice. Cell 46: 13-18.
39. Small JA, Khoury G, Jay G, Howley PM, Scangos GA (1986b). Early regions of JC virus and BK virus induce distinct and tissue-specific tumors in transgenic mice. Proc Natl Acad Sci USA 83: 8288-8292.
40. Staib C, Pesh J, Gerwig R, Gerber J-K, Brehm U, Stangl A, Grummt F (1996). p53 inhibits JC virus DNA replication in vivo and interacts with JC virus large T-antigen. Virology 219: 237-246.
41. Stewart AR, Lednicky JA, Butel JS (1998). Sequence analyses of human tumor-associated SV40 DNAs and SV40 viral isolates from monkeys and humans. J Neurovirol 4: 182-193.
42. Theile M, Grabowski G (1990). Mutagenic activity of BKV and JCV in human and other mammalian cells. Arch Virol 113: 221-233.
43. Walker DL, Padgett BL, ZuRhein GM, Albert AE, Marsh RF (1973). Human papovavirus (JC): induction of brain tumors in hamsters. Science 181: 674-676.
44. Wikstrand CJ, Reist CJ, Archer GE, Zalutsky MR, Bigner DD (1998). The class m variant of the epidermal growth factor receptor (EGFRvIII): characterization and utilization as an immunotherapeutic target. J Neurovirol 4: 148-158.
45. Williamson PJ, Allan NC, McIntyre MA (1989). Cerebral Hodgkin's disease and progressive multifocal leukoencephalopathy. Clin Lab Haemat 11: 281-285.
46. ZuRhein GM (1983). Studies of JCV-induced nervous system tumors in the Syrian hamster: a review. In: Polyomavaviruses and human neurological diseases. Alan R Liss Inc: New York. pp. 205-221.