Hybridized and isosteric analogues of N1-acetyl-N4-dimethyl-piperazinium iodide (ADMP) and N1-phenyl-N4-dimethyl-piperazinium iodide (DMPP) with central nicotinic action

Bioorganic and Medicinal Chemistry

Volumn 7, Issue 3, 1999, Pages 457-465

  Manetti, Dina ^a   Bartolini, Alessandro ^a   Borea, Pier Andrea ^b   Bellucci, Cristina ^a   Dei, Silvia ^a   Ghelardini, Carla ^a   Gualtieri, Fulvio ^a   Romanelli, Maria Novella ^a   Scapecchi, Serena ^a   Teodori, Elisabetta ^a   Varani, Katia ^b  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF FERRARA   (Italy)

Author keywords

Analgesics; Cognition enhances; Nicotinic receptor; Piperazine

Indexed keywords

1,1 DIMETHYL 4 PHENYLPIPERAZINIUM; 4 ACETYL 1,1 DIMETHYLPIPERAZINIUM IODIDE; ARECOLINE; CYTISINE; MORPHINE; NICOTINE; NICOTINIC RECEPTOR; PIPERAZINE DERIVATIVE; SCOPOLAMINE;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTICHOLINERGIC EFFECT; ANTINOCICEPTION; ARTICLE; BRAIN CORTEX; CHEMICAL MODIFICATION; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; HYBRIDIZATION; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PASSIVE AVOIDANCE; RAT; REACTION ANALYSIS;

ANALGESICS; ANIMALS; BRAIN; DIMETHYLPHENYLPIPERAZINIUM IODIDE; GUINEA PIGS; ILEUM; ISOMERISM; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MICE; PIPERAZINES; QUATERNARY AMMONIUM COMPOUNDS; RATS; RATS, WISTAR; RECEPTORS, NICOTINIC; SPECTROPHOTOMETRY, INFRARED;

EID: 0032977664     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(98)00259-4     Document Type: Article

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