메뉴 건너뛰기




Volumn 314, Issue 4, 2001, Pages 717-733

DNA recombination and RNA cleavage activities of the Flp protein: Roles of two histidine residues in the orientation and activation of the nucleophile for strand cleavage

Author keywords

Catalytic complementation; Flp RNase I; Flp RNase II; Half site recombination; Shared active site

Indexed keywords

HISTIDINE; RECOMBINASE;

EID: 0035824864     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2001.5194     Document Type: Article
Times cited : (5)

References (43)
  • 7
    • 0026701381 scopus 로고
    • Reactions between half- and full-FLP recombination target sites. A model system for analyzing early steps in FLP protein-mediated site-specific recombination
    • (1992) J. Biol. Chem. , vol.267 , pp. 7794-7805
    • Qian, X.H.1    Inman, R.B.2    Cox, M.M.3
  • 12
    • 0027193305 scopus 로고
    • Tests for the fractional active-site model in Flp site-specific recombination. Assembly of a functional recombination complex in half-site and full-site strand transfer
    • (1993) J. Biol. Chem. , vol.268 , pp. 14417-14425
    • Chen, J.W.1    Yang, S.H.2    Jayaram, M.3
  • 14
    • 0027248517 scopus 로고
    • Mechanism of site-specific recombination. Logic of assembling recombinase catalytic site from fractional active sites
    • (1993) J. Biol. Chem. , vol.268 , pp. 17564-17570
    • Lee, J.1    Jayaram, M.2
  • 15
    • 0026748245 scopus 로고
    • Ligation activity of FLP recombinase. The strand ligation activity of a site-specific recombinase using an activated DNA substrate
    • (1992) J. Biol. Chem. , vol.267 , pp. 12397-12399
    • Pan, G.1    Sadowski, P.D.2
  • 26
    • 0008061592 scopus 로고    scopus 로고
    • Theme and variations in tyrosine recombinases: Structure of a Flp-DNA complex
    • (Craig, N. L. et al., eds), ASM Press, Washington, DC
    • (2001) Mobile DNA II
    • Rice, P.A.1
  • 30
    • 0026717832 scopus 로고
    • Mutagenesis of a conserved region of the gene encoding the FLP recombinase of Saccharomyces cerevisiae. A role for arginine-191 in binding and ligation
    • (1992) J. Mol. Biol. , vol.225 , pp. 313-326
    • Friesen, H.1    Sadowski, P.D.2
  • 41
    • 0026651559 scopus 로고
    • DNA cleavage in trans by the active site tyrosine during Flp recombination: Switching protein partners before exchanging strands
    • (1992) Cell , vol.69 , pp. 647-658
    • Chen, J.-W.1    Lee, J.2    Jayaram, M.3
  • 43
    • 0029993536 scopus 로고    scopus 로고
    • Assembly and orientation of Flp recombinase active sites on two-, three-, and four-armed DNA substrates: Implications for a recombination mechanism
    • (1996) J. Mol. Biol. , vol.257 , pp. 532-549
    • Lee, J.1    Whang, I.2    Jayaram, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.