메뉴 건너뛰기




Volumn 1, Issue 5, 1998, Pages 729-739

Unveiling two distinct ribonuclease activities and a topoisomerase activity in a site-specific DNA recombinase

Author keywords

[No Author keywords available]

Indexed keywords

DNA POLYMERASE; DNA TOPOISOMERASE; FUNGAL PROTEIN; FUNGAL RNA; RECOMBINASE; RIBONUCLEASE;

EID: 0032037326     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(00)80072-6     Document Type: Article
Times cited : (36)

References (46)
  • 1
    • 0024935821 scopus 로고
    • RNA splicing in yeast
    • Abelson, J. (1991). RNA splicing in yeast. Harvey Lect. 85, 1-42.
    • (1991) Harvey Lect. , vol.85 , pp. 1-42
    • Abelson, J.1
  • 2
    • 0022626134 scopus 로고
    • Properties of a mutant Cre protein that alters the topological linkage of recombination products
    • Abremski, K., Wierzbicki, A., Frommer, B., and Hoess, R.H. (1986). Properties of a mutant Cre protein that alters the topological linkage of recombination products. J. Biol. Chem. 261, 391-396.
    • (1986) J. Biol. Chem. , vol.261 , pp. 391-396
    • Abremski, K.1    Wierzbicki, A.2    Frommer, B.3    Hoess, R.H.4
  • 3
    • 0026649231 scopus 로고
    • Directed evolution of an RNA enzyme
    • Beaudry, A.A., and Joyce, G.F. (1992). Directed evolution of an RNA enzyme. Science 257, 635-641.
    • (1992) Science , vol.257 , pp. 635-641
    • Beaudry, A.A.1    Joyce, G.F.2
  • 4
    • 0000560681 scopus 로고
    • Circular DNA plasmids of yeasts: Genome dynamics, protein synthesis and energetics
    • J. R. Broach, J.R. Pringle and E.W. Jones, eds. (Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press)
    • Broach, J.R., and Volkert, F.C. (1991). Circular DNA plasmids of yeasts: genome dynamics, protein synthesis and energetics. In The Molecular and Cellular Biology of the Yeast Saccharomyces, J. R. Broach, J.R. Pringle and E.W. Jones, eds. (Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press), pp. 297-331.
    • (1991) The Molecular and Cellular Biology of the Yeast Saccharomyces , pp. 297-331
    • Broach, J.R.1    Volkert, F.C.2
  • 5
    • 0344110202 scopus 로고    scopus 로고
    • Can DNA topoisomerases be ribonucleases?
    • Burgin, A.B., Jr. (1997). Can DNA topoisomerases be ribonucleases? Cell 91, 873-874.
    • (1997) Cell , vol.91 , pp. 873-874
    • Burgin A.B., Jr.1
  • 6
    • 0017757667 scopus 로고
    • 3′-phosphatase activity in T4 polynucleotide kinase
    • Cameron, V., and Uhlenbeck, O.C. (1977). 3′-phosphatase activity in T4 polynucleotide kinase. Biochemistry 16, 5120-5126.
    • (1977) Biochemistry , vol.16 , pp. 5120-5126
    • Cameron, V.1    Uhlenbeck, O.C.2
  • 7
    • 0027176526 scopus 로고
    • RNA. Fishing for fresh catalysts
    • Cech, T.R. (1993). RNA. Fishing for fresh catalysts. Nature 365, 204-205.
    • (1993) Nature , vol.365 , pp. 204-205
    • Cech, T.R.1
  • 8
    • 0002754552 scopus 로고    scopus 로고
    • Group I ribozymes: Substrate recognition, catalytic strategies, and comparative mechanistic analysis
    • F. Eckstein and D.M.J. Lilley, eds., (Berlin: Springer-Verlag)
    • Cech, T.R., and Herschlag, D. (1996). Group I ribozymes: substrate recognition, catalytic strategies, and comparative mechanistic analysis. In Nucleic Acids and Molecular Biology, F. Eckstein and D.M.J. Lilley, eds., (Berlin: Springer-Verlag) 10, 1-18.
    • (1996) Nucleic Acids and Molecular Biology , vol.10 , pp. 1-18
    • Cech, T.R.1    Herschlag, D.2
  • 9
    • 0026641669 scopus 로고
    • Functional analysis of Box I mutations in yeast site-specific recombinases Flp and R: Pairwise complementation with recombinase variants lacking the active site tyrosine
    • Chen, J.-W., Evans, B.R., Yang, S.H., Araki, H., and Oshima, Y. (1992a). Functional analysis of Box I mutations in yeast site-specific recombinases Flp and R: pairwise complementation with recombinase variants lacking the active site tyrosine. Mol. Cell. Biol. 12, 3757-3765.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 3757-3765
    • Chen, J.-W.1    Evans, B.R.2    Yang, S.H.3    Araki, H.4    Oshima, Y.5
  • 10
    • 0026651559 scopus 로고
    • DNA cleavage in trans by the active site tyrosine during Flp recombination: Switching protein partners before exchanging strands
    • Chen, J.-W., Lee, J., and Jayaram, M. (1992b). DNA cleavage in trans by the active site tyrosine during Flp recombination: switching protein partners before exchanging strands. Cell 69, 647-658.
    • (1992) Cell , vol.69 , pp. 647-658
    • Chen, J.-W.1    Lee, J.2    Jayaram, M.3
  • 11
    • 0028279785 scopus 로고
    • The covalent eukaryotic topoisomerase I-DNA intermediate catalyzes pH-dependent hydrolysis and alcoholysis
    • Christiansen, K., Knudsen, B.R., and Westergaard, O. (1994). The covalent eukaryotic topoisomerase I-DNA intermediate catalyzes pH-dependent hydrolysis and alcoholysis. J. Biol. Chem. 269, 11367-11373.
    • (1994) J. Biol. Chem. , vol.269 , pp. 11367-11373
    • Christiansen, K.1    Knudsen, B.R.2    Westergaard, O.3
  • 12
    • 0030881917 scopus 로고    scopus 로고
    • Xer recombination in E. coli: Site-specific topoisomerase activity of the XerC and XerD recombinases
    • Cornet, F., Hallet, B., and Sherratt, D.J. (1997). Xer recombination in E. coli: site-specific topoisomerase activity of the XerC and XerD recombinases. J. Biol. Chem. 272, 21927-21931.
    • (1997) J. Biol. Chem. , vol.272 , pp. 21927-21931
    • Cornet, F.1    Hallet, B.2    Sherratt, D.J.3
  • 13
    • 0009210820 scopus 로고
    • Evolution of DNA topology: Implications for its biological roles
    • Cozzarelli, N.R. (1992). Evolution of DNA topology: implications for its biological roles. Proc. Symp. Appl. Math. 45, 1-16.
    • (1992) Proc. Symp. Appl. Math. , vol.45 , pp. 1-16
    • Cozzarelli, N.R.1
  • 14
    • 0029037713 scopus 로고
    • A DNA metalloenzyme with DNA ligase activity
    • Cuenoud, B., and Szostak, J.W. (1995). A DNA metalloenzyme with DNA ligase activity. Nature 375, 611-614.
    • (1995) Nature , vol.375 , pp. 611-614
    • Cuenoud, B.1    Szostak, J.W.2
  • 15
    • 0030816550 scopus 로고    scopus 로고
    • The integrase family of tyrosine recombinases: Evolution of a conserved active site domain
    • Esposito, D., and Scocca, J.J. (1997) The integrase family of tyrosine recombinases: evolution of a conserved active site domain. Nucleic Acids Res. 25, 3605-3614.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 3605-3614
    • Esposito, D.1    Scocca, J.J.2
  • 16
    • 0011877042 scopus 로고
    • Chapter 15. Structures and mechanisms of selected enzymes
    • New York: W.H. Freeman and Co.
    • Fersht, A.F. (1984). Chapter 15. Structures and mechanisms of selected enzymes. In Enzyme Structure and Mechanism (New York: W.H. Freeman and Co.), pp. 426-434.
    • (1984) Enzyme Structure and Mechanism , pp. 426-434
    • Fersht, A.F.1
  • 17
    • 0030886293 scopus 로고    scopus 로고
    • Structure of cre recombinase complexed with DNA in a site-specific recombination synapse
    • Guo, F., Gopaul, D.N., and Van Duyne, G.D. (1997). Structure of Cre recombinase complexed with DNA in a site-specific recombination synapse. Nature 389, 40-45.
    • (1997) Nature , vol.389 , pp. 40-45
    • Guo, F.1    Gopaul, D.N.2    Van Duyne, G.D.3
  • 18
    • 0030904786 scopus 로고    scopus 로고
    • Molecular organization in site-specific recombination: The catalytic domain of bacteriophage HP1 integrase at 2.7 Å resolution
    • Hickman, A.B., Waniger, S., Scocca, J.J., and Dyda F. (1997). Molecular organization in site-specific recombination: the catalytic domain of bacteriophage HP1 integrase at 2.7 Å resolution. Cell 89, 227-237.
    • (1997) Cell , vol.89 , pp. 227-237
    • Hickman, A.B.1    Waniger, S.2    Scocca, J.J.3    Dyda, F.4
  • 19
    • 0011167645 scopus 로고
    • Mechanism of site-specific recombination: The Flp paradigm
    • F. Eckstein and D.M.J. Lilley, eds. (Springer-Verlag)
    • Jayaram, M. (1994). Mechanism of site-specific recombination: the Flp paradigm. Nucleic Acids and Mol. Biol., F. Eckstein and D.M.J. Lilley, eds. (Springer-Verlag) 8, 268-286.
    • (1994) Nucleic Acids and Mol. Biol. , vol.8 , pp. 268-286
    • Jayaram, M.1
  • 20
    • 0024476917 scopus 로고
    • RNA evolution and the origins of life
    • Joyce, G.F. (1989). RNA evolution and the origins of life. Nature. 338, 217-224.
    • (1989) Nature , vol.338 , pp. 217-224
    • Joyce, G.F.1
  • 21
    • 2642665308 scopus 로고
    • Nicking-closing activity associated with bacteriophage lambda Int gene product
    • Kikuchi, Y., and Nash, H.A. (1979). Nicking-closing activity associated with bacteriophage lambda Int gene product. Proc. Natl. Acad. Sci. USA 76, 3760-3764.
    • (1979) Proc. Natl. Acad. Sci. USA , vol.76 , pp. 3760-3764
    • Kikuchi, Y.1    Nash, H.A.2
  • 22
    • 0027277026 scopus 로고
    • Sequence-specific cleavage of DNA via nucleophilic attack of hydrogen peroxide, assisted by Flp recombianse
    • Kimball, A., Lee, J., Jayaram, M.,and Tullius, T.D. (1993). Sequence-specific cleavage of DNA via nucleophilic attack of hydrogen peroxide, assisted by Flp recombianse. Biochemistry 32, 4698-4701.
    • (1993) Biochemistry , vol.32 , pp. 4698-4701
    • Kimball, A.1    Lee, J.2    Jayaram, M.3    Tullius, T.D.4
  • 23
    • 0023724432 scopus 로고
    • Novel splicing mechnaism for the ribosomal RNA intron in the Archaebacterium Desulfurococcus mobilis
    • Kjems, J., and Garrett, R.A. (1988). Novel splicing mechnaism for the ribosomal RNA intron in the Archaebacterium Desulfurococcus mobilis. Cell 54, 693-703.
    • (1988) Cell , vol.54 , pp. 693-703
    • Kjems, J.1    Garrett, R.A.2
  • 24
    • 0031566951 scopus 로고    scopus 로고
    • The yeast site-specific recombinase Flp mediates alcoholysis and hydrolysis of the strand cleavage product: Mimicking the strand joining reaction with non-DNA nucleophiles
    • Knudsen, B.R., Dahlstrom, K., Westergaard, O., and Jayaram, M. (1997). The yeast site-specific recombinase Flp mediates alcoholysis and hydrolysis of the strand cleavage product: mimicking the strand joining reaction with non-DNA nucleophiles. J. Mol. Biol. 266, 93-107.
    • (1997) J. Mol. Biol. , vol.266 , pp. 93-107
    • Knudsen, B.R.1    Dahlstrom, K.2    Westergaard, O.3    Jayaram, M.4
  • 25
    • 0001656001 scopus 로고    scopus 로고
    • Flexibility in DNA recombination: Structure of the lambda integrase catalytic core
    • Kwon, J.K., Tirumalai, R., Landy, A., and Ellenberger, T. (1997). Flexibility in DNA recombination: structure of the lambda integrase catalytic core. Science 276, 126-131.
    • (1997) Science , vol.276 , pp. 126-131
    • Kwon, J.K.1    Tirumalai, R.2    Landy, A.3    Ellenberger, T.4
  • 26
    • 0027435209 scopus 로고
    • Mechanistic and structural complexity in the site-specific recombination pathways of Int and FLP
    • Landy, A. (1993). Mechanistic and structural complexity in the site-specific recombination pathways of Int and FLP. Curr. Opin. Genet. Dev. 3, 699-707.
    • (1993) Curr. Opin. Genet. Dev. , vol.3 , pp. 699-707
    • Landy, A.1
  • 27
    • 0027093070 scopus 로고
    • Functional analysis of Box II mutations in yeast site-specific recombinase Flp and R; significance of amino acid conservation within the int family and the yeast subfamily
    • Lee, J., Serre, M.C., Yang, S.H., Whang, I., Araki, H., and Oshima, Y., and Jayaram, M. (1992). Functional analysis of Box II mutations in yeast site-specific recombinase Flp and R; significance of amino acid conservation within the Int family and the yeast subfamily. J. Mol. Biol. 228, 1091-1103.
    • (1992) J. Mol. Biol. , vol.228 , pp. 1091-1103
    • Lee, J.1    Serre, M.C.2    Yang, S.H.3    Whang, I.4    Araki, H.5    Oshima, Y.6    Jayaram, M.7
  • 28
    • 0027248517 scopus 로고
    • Mechanism of site-specific recombination: Logic of assembling the recombinase catalytic site from fractional active sites
    • Lee, J., and Jayaram, M. (1993). Mechanism of site-specific recombination: logic of assembling the recombinase catalytic site from fractional active sites. J. Biol. Chem. 268, 17564-17579.
    • (1993) J. Biol. Chem. , vol.268 , pp. 17564-17579
    • Lee, J.1    Jayaram, M.2
  • 29
    • 0029088838 scopus 로고
    • Functional roles of individual recombinase monomers in strand breakage and strand reunion during site-specific DNA recombination
    • Lee, J., and Jayaram, M. (1995). Functional roles of individual recombinase monomers in strand breakage and strand reunion during site-specific DNA recombination. J. Biol. Chem. 270, 23203-23211.
    • (1995) J. Biol. Chem. , vol.270 , pp. 23203-23211
    • Lee, J.1    Jayaram, M.2
  • 30
    • 0029993536 scopus 로고    scopus 로고
    • Assembly and orientation of Flp recombinase active sites on two-, three- and four-armed DNA substrates: Implication fora recombination mechanism
    • Lee, J., Whang, I., and Jayaram, M. (1996) Assembly and orientation of Flp recombinase active sites on two-, three-and four-armed DNA substrates: implication fora recombination mechanism. J. Mol. Biol. 257, 532-549.
    • (1996) J. Mol. Biol. , vol.257 , pp. 532-549
    • Lee, J.1    Whang, I.2    Jayaram, M.3
  • 31
    • 0028124128 scopus 로고
    • In vitro evolution of new ribozymes with polynucleotide kinase activity
    • Lorsch, J.R., and Szostak, J.W. (1994). In vitro evolution of new ribozymes with polynucleotide kinase activity. Nature 371, 31-36.
    • (1994) Nature , vol.371 , pp. 31-36
    • Lorsch, J.R.1    Szostak, J.W.2
  • 32
    • 9844256088 scopus 로고    scopus 로고
    • A bacterial group II intron encoding reverse transcriptase, maturase and DNA endonuclease activities: Biochemical demonstration of maturase activity and insertion of new genetic information within the intron
    • Matsuura, M., Saldhana, R., Ma, H., Wank, H., Yang, J., Mohr, G., Cavanagh, S., Dunny, G., Belfort, M., and Lambowitz, A. (1997). A bacterial group II intron encoding reverse transcriptase, maturase and DNA endonuclease activities: biochemical demonstration of maturase activity and insertion of new genetic information within the intron. Genes Dev. 11, 2910-2924.
    • (1997) Genes Dev. , vol.11 , pp. 2910-2924
    • Matsuura, M.1    Saldhana, R.2    Ma, H.3    Wank, H.4    Yang, J.5    Mohr, G.6    Cavanagh, S.7    Dunny, G.8    Belfort, M.9    Lambowitz, A.10
  • 33
    • 0026748245 scopus 로고
    • Ligation activity of FLP recombinase: The strand ligation activity of a site-specific recombinase using an activated DNA substrate
    • Pan G., and Sadowski, P.D. (1992). Ligation activity of FLP recombinase: the strand ligation activity of a site-specific recombinase using an activated DNA substrate. J. Biol. Chem. 267, 12397-12399.
    • (1992) J. Biol. Chem. , vol.267 , pp. 12397-12399
    • Pan, G.1    Sadowski, P.D.2
  • 34
    • 0027159168 scopus 로고
    • Mechanism of cleavage and ligation by FLP recombinase: Classification of mutations in FLP protein by in vitro complementation analysis
    • Pan, G., Luetke, K., and Sadowski, P.D. (1993). Mechanism of cleavage and ligation by FLP recombinase: classification of mutations in FLP protein by in vitro complementation analysis. Mol. Cell. Biol. 13, 3167-3175.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 3167-3175
    • Pan, G.1    Luetke, K.2    Sadowski, P.D.3
  • 35
    • 0023708318 scopus 로고
    • Step-arrest mutants of Flp recombinase: Implications for the catalytic mechanism of DNA recombination
    • Parsons, R.L., Prasad, P.V., Harshey, R.M., and Jayaram, M. (1988). Step-arrest mutants of Flp recombinase: implications for the catalytic mechanism of DNA recombination. Mol. Cell. Biol. 8, 3303-3310.
    • (1988) Mol. Cell. Biol. , vol.8 , pp. 3303-3310
    • Parsons, R.L.1    Prasad, P.V.2    Harshey, R.M.3    Jayaram, M.4
  • 36
    • 0025264936 scopus 로고
    • Functional analyses of Arg-308 mutants of Flp recombinase: Possible role of Arg-308 in coupling substrate binding to catalysis
    • Parsons, R.L., Evans, B.R., Zheng, L., and Jayaram, M. (1990). Functional analyses of Arg-308 mutants of Flp recombinase: possible role of Arg-308 in coupling substrate binding to catalysis. J. Biol. Chem. 265, 4527-4533.
    • (1990) J. Biol. Chem. , vol.265 , pp. 4527-4533
    • Parsons, R.L.1    Evans, B.R.2    Zheng, L.3    Jayaram, M.4
  • 37
    • 0020710638 scopus 로고
    • Precise excision of intervening sequences from precursor tRNAs by a membrane-associated yeast endonuclease
    • Peebles, C.L., Gegenheimer, P., and Abelson, J. (1983). Precise excision of intervening sequences from precursor tRNAs by a membrane-associated yeast endonuclease. Cell 32, 525-536.
    • (1983) Cell , vol.32 , pp. 525-536
    • Peebles, C.L.1    Gegenheimer, P.2    Abelson, J.3
  • 38
    • 0023322410 scopus 로고
    • Mutations in the 2-micron circle site-specific recombinase that abolish recombination without affecting substrate recognition
    • Prasad, P.V., Young, L.J., and Jayaram, M. (1987). Mutations in the 2-micron circle site-specific recombinase that abolish recombination without affecting substrate recognition. Proc. Natl. Acad. Sci. USA 84, 2189-2193.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 2189-2193
    • Prasad, P.V.1    Young, L.J.2    Jayaram, M.3
  • 39
    • 0026701381 scopus 로고
    • Reactions between half- and full-FLP recombination target sites. A model system for analyzing early steps in FLP protein-mediated site-specific recombination
    • Qian, X.-H., Inman, R.B., and Cox, M.M. (1992). Reactions between half-and full-FLP recombination target sites. A model system for analyzing early steps in FLP protein-mediated site-specific recombination. J. Biol. Chem. 267, 7794-7805.
    • (1992) J. Biol. Chem. , vol.267 , pp. 7794-7805
    • Qian, X.-H.1    Inman, R.B.2    Cox, M.M.3
  • 40
    • 0027173542 scopus 로고
    • Site-specific genetic recombination: Hops, flips, and flops
    • Sadowski, P.D. (1993). Site-specific genetic recombination: hops, flips, and flops. FASEB J. 7, 760-767.
    • (1993) FASEB J. , vol.7 , pp. 760-767
    • Sadowski, P.D.1
  • 42
    • 0031310666 scopus 로고    scopus 로고
    • Site-specific ribonuclease activity of eukaryotic DNA topoisomerase I
    • Sekiguchi, J., and Shuman, S. (1997). Site-specific ribonuclease activity of eukaryotic DNA topoisomerase I. Mol. Cell 1, 89-97.
    • (1997) Mol. Cell , vol.1 , pp. 89-97
    • Sekiguchi, J.1    Shuman, S.2
  • 43
    • 0026622965 scopus 로고
    • Half-site recombinations mediated by yeast site-specific recombinases Flp and R
    • Serre, M.C., Evans, B.R., Araki, H., Oshima, Y., and Jayaram, M. (1992). Half-site recombinations mediated by yeast site-specific recombinases Flp and R. J. Mol. Biol. 225, 621-642.
    • (1992) J. Mol. Biol. , vol.225 , pp. 621-642
    • Serre, M.C.1    Evans, B.R.2    Araki, H.3    Oshima, Y.4    Jayaram, M.5
  • 46
    • 0029931406 scopus 로고    scopus 로고
    • Efficient integration of an intron RNA into double-stranded DNA by reverse splicing
    • Yang, J., Zimmerly, S., Perlman, P.S., and Lambowitz, A.M. (1996). Efficient integration of an intron RNA into double-stranded DNA by reverse splicing. Nature 381, 280-281.
    • (1996) Nature , vol.381 , pp. 280-281
    • Yang, J.1    Zimmerly, S.2    Perlman, P.S.3    Lambowitz, A.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.