SCOPUS 정보 검색 플랫폼

Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 11, 2001, Pages 1355-1358

Identification of novel potent hydroxamic acid inhibitors of peptidyl deformylase and the importance of the hydroxamic acid functionality on inhibition

(15) Thorarensen, Atli a Douglas Jr , Martin R b Rohrer, Douglas C c Vosters, Anne F b Yem, Anthony W b Marshall, Vincent D b Lynn, Janet C d Bohanon, Michael J d Tomich, Paul K d Zurenko, Gary E e Sweeney, Michael T e Jensen, Randy M f Nielsen, James W f Seest, Eric P f Dolak, Lester A f

a Pharmacia (United States)

b Protein Science (United States)

c NONE (United States)

d Discovery Technologies (United States)

e Biology i (United States)

f Structural (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITOR; HYDROXAMIC ACID INHIBITOR; HYDROXYUREA; METALLOPROTEINASE; PEPTIDYL DEFORMYLASE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG BINDING; DRUG EFFECT; DRUG IDENTIFICATION; DRUG SCREENING; ENZYME INHIBITION; IC 50; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; STAPHYLOCOCCUS AUREUS;

AMIDOHYDROLASES; AMINOPEPTIDASES; ANTI-BACTERIAL AGENTS; HYDROXAMIC ACIDS; METALLOENDOPEPTIDASES; MICROBIAL SENSITIVITY TESTS; MODELS, MOLECULAR; PROTEIN CONFORMATION; STAPHYLOCOCCUS AUREUS; STRUCTURE-ACTIVITY RELATIONSHIP;

BACTERIA (MICROORGANISMS); PROKARYOTA; STAPHYLOCOCCUS AUREUS;

EID: 0035806083 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/S0960-894X(01)00242-6 Document Type: Article

Times cited : (30)

References (28)

1
- 0026705492
- (1992) Science , vol.257 , pp. 1050
- Cohen, M.L.¹

2
- 0029437590
- Ellis, G. P., Luscombe, D. K., Eds.; Elsevier Science: New York
- (1995) Progress in Medicinal Chemistry , vol.32 , Issue.CHAPTER 4 , pp. 157
- Allen, N.E.¹

3
- 0025612231
- (1990) Biochem. J. , vol.272 , pp. 281
- Hayes, J.D.¹ Wolf, C.R.²

4
- 0028420272
- (1994) Science , vol.264 , pp. 388
- Spratt, B.G.¹

5
- 23444456920
- (1994) Science , vol.264 , pp. 382
- Nikaido, H.¹

6
- 34250309284
- Ellis, G. P., Luscombe, D. K., Oxford, A. W., Eds.; Elsevier Science: New York
- (1998) Progress in Medicinal Chemistry , vol.35 , Issue.CHAPTER 4
- Russell, A.D.¹

7
- 0001802381
- (1998) Naturwissenschaften , vol.85 , pp. 99
- Fuchs, T.M.¹

8
- 0031946506
- (1998) Curr. Med. Chem. , vol.5 , pp. 101
- Setti, E.L.¹ Micetich, R.G.²

9
- 0004912569
- (1997) Annu. Rep. Med. Chem. , vol.32 , pp. 121
- Katz, L.¹ Chu, D.T.² Reich, K.³

10
- 0030862838
- (1997) Expert Opin. Invest. Drugs , vol.6 , pp. 1019
- Chopra, I.¹

11
- 0030723134
- (1997) Curr. Opin. Biotechnol. , vol.8 , pp. 757
- Isaacson, R.E.¹ Trias, J.² Gordon, E.M.³

12
- 0030723134
- (1997) Curr. Opin. Biotechnol. , vol.8 , pp. 757
- Trias, J.¹ Gordon, E.M.²

13
- 0032540979
- (1998) J. Mol. Biol. , vol.280 , pp. 515
- Ragusa, S.¹ Blanquet, S.² Meinnel, T.³

14
- 0032540851
- (1998) J. Mol. Biol. , vol.280 , pp. 501
- Dardel, F.¹ Ragusa, S.² Lazennec, C.³ Blanquet, S.⁴ Meinnel, T.⁵

15
- 0032946577
- (1999) J. Biomolecular NMR , vol.13 , pp. 311
- O'Connell, J.F.¹ Pryor, K.A.D.² Grant, S.K.³ Leiting, B.⁴

16
- 0031730185
- (1998) Nat. Struct. Biol. , vol.5 , pp. 1053
- Becker, A.¹ Schlichting, I.² Kabsch, W.³ Groche, D.⁴ Schultz, S.⁵ Wagner, A.F.V.⁶

17
- 0033551093
- (1999) Biochemistry , vol.38 , pp. 4712
- Hao, B.¹ Gong, W.² Rajagopalan, P.T.R.³ Zhou, I.⁴ Pei, D.⁵ Chan, M.K.⁶

18
- 0034673093
- (2000) Biochemistry , vol.39 , pp. 1256
- Chen, D.Z.¹ Patel, D.V.² Hackbarth, C.J.³ Wang, W.⁴ Dreyer, G.⁵ Young, D.C.⁶ Margolis, P.S.⁷ Wu, C.⁸ Ni, Z.-J.⁹ Trias, J.¹⁰ White, R.J.¹¹ Yuan, Z.¹²

19
- 17644447403
- (2000) J. Med. Chem. , vol.43 , pp. 2324
- Apfel, C.¹ Banner, D.W.² Bur, D.³ Dietz, M.⁴ Hirata, T.⁵ Hubschwerlen, C.⁶ Locher, H.⁷ Page, M.G.P.⁸ Pirson, W.⁹ Rosse, G.¹⁰ Specklin, J.-L.¹¹

20
- 0004886478
- WO 9939704A1
- (1999) Chem. Abstr. , vol.131 , pp. 144852
- Hunter, M.G.¹ Beckett, R.P.² Clements, J.M.³ Whittaker, M.⁴ Davies, S.J.⁵ Pratt, L.M.⁶ Spavold, Z.M.⁷ Launchbury, S.⁸

21
- 0004862745
- WO 0035440A1
- (2000) Chem. Abstr. , vol.133 , pp. 59097
- Hunter, M.G.¹ Beckett, R.P.² Clements, J.M.³ Whittaker, M.⁴

22
- 0034681924
- (2000) Biochemistry , vol.39 , pp. 4543
- Huntington, K.M.¹ Yi, T.² Wei, Y.³ Pei, D.⁴

23
- 0034654564
- (2000) Arch. Biochem. Biophys. , vol.375 , pp. 355
- Green, B.G.¹ Toney, J.H.² Kozarich, J.W.³ Grant, S.K.⁴

24
- 0004903630
- Poster, French-American Chemical Society FACS VIII, Sonoma County, CA, June
- (2000) Preliminary disclosure: Identification of Novel Potent Hydroxamic Acid Inhibitors of Peptidyl Deformylas

25
- 0031571098
- (1997) Anal. Biochem. , vol.250 , pp. 29
- Wei, Y.¹ Pei, D.²

26
- 0031025121
- (1997) Anal. Biochem. , vol.244 , pp. 180
- Lazennec, C.¹ Meinnel, T.²

27
- 0004842693
- Compounds not shown but are related to 16

28
- 0004862746
- The antibacterial activity of 16 is due to an unknown mechanism and appears to be unrelated to PDF

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.