Topical application of the cornea post-infection with plasmid DNA encoding interferon-α1 but not recombinant interferon-αA reduces herpes simplex virus type 1-induced mortality in mice

Journal of Neuroimmunology

Volumn 121, Issue 1-2, 2001, Pages 49-58

  Noisakran, Sansanee ^a   Carr, Daniel J J ^a  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

Cornea; HSV 1; Interferon ; Naked DNA; Viral replication

Indexed keywords

ALPHA1 INTERFERON; CD11B ANTIGEN; GLYCOPROTEIN P 15095; PLASMID DNA; RECOMBINANT ALPHA INTERFERON A;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHRONOTHERAPY; CONTROLLED STUDY; CORNEA; CORRELATION FUNCTION; DRUG EFFICACY; DRUG SPECIFICITY; FEMALE; GENE EXPRESSION; HERPES SIMPLEX KERATITIS; HERPES SIMPLEX VIRUS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN; SURVIVAL TIME; TRANSGENE; TRIGEMINUS GANGLION; VIRUS LOAD; VIRUS REPLICATION; VIRUS TITRATION;

ADMINISTRATION, TOPICAL; ANIMALS; CERCOPITHECUS AETHIOPS; CORNEA; CORNEAL DISEASES; FEMALE; GENE THERAPY; HERPES SIMPLEX; HERPESVIRUS 1, HUMAN; INTERFERON TYPE I, RECOMBINANT; INTERFERON-ALPHA; MICE; MICE, INBRED ICR; PLAQUE ASSAY; PLASMIDS; VERO CELLS; VIRAL LOAD; VIRUS REPLICATION;

EID: 0035803836     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(01)00442-8     Document Type: Article

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