Astrocyte-targeted expression of IFN-α1 protects mice from acute ocular herpes simplex virus type 1 infection

Journal of Immunology

Volumn 161, Issue 9, 1998, Pages 4859-4865

  Carr, Daniel J J ^a   Veress, Livia A ^b   Noisakran, Sansanee ^b   Campbell, Iain L ^b  

^a LOUISIANA STATE UNIV MEDICAL CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA1 INTERFERON; CD8 ANTIGEN; GAMMA INTERFERON; GLIAL FIBRILLARY ACIDIC PROTEIN; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; POLYPEPTIDE; RANTES; VIRUS ANTIBODY; VIRUS DNA;

ANIMAL MODEL; ANTIVIRAL ACTIVITY; ARTICLE; ASTROCYTE; DNA REPLICATION; HERPES SIMPLEX; HERPES SIMPLEX KERATITIS; HERPES SIMPLEX VIRUS 1; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIRUS DETECTION; VIRUS REPLICATION;

ANIMALS; ASTROCYTES; DISEASE SUSCEPTIBILITY; GENE EXPRESSION REGULATION; GLIAL FIBRILLARY ACIDIC PROTEIN; INTERFERON-ALPHA; KERATITIS, HERPETIC; MICE; MICE, TRANSGENIC; RECOMBINANT FUSION PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIMPLEXVIRUS; TRIGEMINAL GANGLION; VIRUS LATENCY;

EID: 0032212260     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Stevens, J. G., and M. L. Cook. 1974. Maintenance of latent herpetic infection: an apparent role for anti-viral IgG. J. Immunol. 113:1685.
2. Hendricks, R. L., P. C. Weber, J. L. Taylor, A. Koumbis, T. M. Tumpey, and J. C. Glorioso. 1991. Endogenously produced interferon a protects mice from herpes simplex virus type 1 corneal disease. J. Gen. Virol. 72:1601.
3. Rinaldo, C. R., and D. J. Torpey. 1993. Cell-mediated immunity and immunosuppression in herpes simplex virus infection. Immunodeficiency 5:33.
4. Cook, M. L., and J. G. Stevens. 1973. Pathogenesis of herpetic neuritis and ganglionitis in mice: evidence for intra-axonal transport infection. Infect. Immun. 7:272.
5. Fraser, N. W., T. Block, and J. G. Spivack. 1992. The latency-associated transcripts of herpes simplex virus: RNA in search of function. Virology 191:1.
6. Kramer, M., and D. M. Coen. 1995. Quantification of transcripts from the ICP4 and thymidine kinase genes in mouse ganglia latently infected with herpes simplex virus. J. Virol. 69:1389.
7. Cantin, E. M., D. R. Hinton, J. Chen, and H, Openshaw. 1995. [Gamma] interferon expression during acute and latent nervous system infection by herpes simplex virus type 1. J. Virol. 69:4898.
8. Shimeld, C., J. L. Whiteland, S. M. Nicholls, E. Grinfeld, D. L. Easty, H. Gao, and T. J. Hill. 1995. Immune cell infiltration and persistence in the mouse trigeminal ganglion after infection of the cornea with herpes simplex virus type 1. J. Neuroimmunol. 61:7.
9. Liu, T., Q. Tang, and R. L. Hendricks. 1996. Inflammatory infiltration of the trigeminal ganglion after herpes simplex virus type 1 corneal infection. J. Virol. 70:264.
10. Halford, W. P., B. M. Gebhardt, and D. J. J. Carr. 1996. Persistent cytokine expression in the trigeminal ganglion latently infected with herpes simplex virus type 1. J. Immunol. 157:3542.
11. Carr, D. J. J., W. P. Halford, L. A. Veress, S. Noisakran, G.-C. Perng, and S. L. Wechsler. 1998. The persistent elevated cytokine mRNA levels in trigeminal ganglia of mice latently infected with HSV-1 are not due to the presence of latency associated transcript (LAT) RNAs. Viral Res. 54:1.
12. Halford, W. P., B. M. Gebhardt, and D. J. J. Carr. 1997. Acyclovir blocks cytokine gene expression in trigeminal ganglia latently infected with herpes simplex virus type 1. Virology 238:53.
13. Lewandowski, G. A., D. Lo, and F. E. Bloom. 1993. Interference with major histocompatibility complex class II-restricted antigen presentation in the brain by herpes simplex virus type 1: a possible mechanism of evasion of the immune response. Proc. Natl. Acad. Sci. USA 90:2005.
14. Johnson, R. E., A. J. Nahmias, L. S. Madger, F. K. Lee, C. Brooks, and C. A. Snowden. 1989. Seroepidemiologic survey of the prevalence of herpes simplex virus type 2 infection in the United States. N. Engl. J. Med. 321:7.
15. Spruance, S. L. 1995. Herpes simplex labialis. In Clinical Management of Herpes Viruses. S. L. Sacks, S. E. Strauss, R. J. Whitely, and P. D. Griffiths, eds. IOS Press, Amsterdam, p. 3.
16. Dawson, C. 1995. Herpes simplex labialis. In Clinical Management of Herpes Viruses. S. L. Sacks, S. E. Strauss, R. J. Whitely, and P. D. Griffiths, eds. IOS Press, Amsterdam, p. 127.
17. Halford, W. P., L. A. Veress, B. M. Gebhardt, and D. J. J. Carr. 1997. Innate and acquired immunity to herpes simplex virus type 1. Virology 236:328.
18. Halford, W. P., L. A. Veress, B. M. Gebhardt, and D. J. J. Carr. 1998. Immunization with HSV-1 antigen rapidly protects against HSV-1-induced encephalitis and is IFN-γ-independent. J. Interferon Cytokine Res. 18:151.
19. Campbell, I. L., C. R. Abraham, E. Masliah, P. Kemper, J. D. Inglis, M. B. A. Oldstone, and L. Mucke. 1996. Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6. Proc. Natl. Acad. Sci. USA 90:10061.
20. Su, Y.-H., X.-T. Yan, J. E. Oakes, and R. N. Lausch. 1996. Protective antibody therapy is associated with reduced chemokine transcripts in herpes simplex virus type 1 corneal infection. J. Virol. 70:1277.
21. Ishikawa, R., and C. A. Biron. 1993. IFN induction and associated changes in splenic leukocyte distribution. J. Immunol. 150:3713.
22. Carr, D. J. J., B. M. Gebhardt, and D. Paul. 1993. [Alpha] adrenergic and μ-2 opioid receptors are involved in morphine-induced suppression of splenocyte natural killer activity. J. Pharmacol. Exp. Ther. 264:1179.
23. Linnavuori, K., and T. Hovi. 1983. Restricted replication of herpes simplex virus in human monocyte cultures: role of interferon. Virology 130:1.
24. Feduchi, E., M. A. Alonso, and L. Carrasco. 1989. Human γ interferon and tumor necrosis factor exert a synergistic blockade on the replication of herpes simplex virus. J. Virol. 63:1354.
25. Belardelli, F., and I. Gresser. 1996. The neglected role of type 1 interferon in the T-cell response: implications for its clinical use. Immunol. Today 17:369.
26. Baron, S., S. K. Tyring, W. R. Fleischmann Jr., D. H. Coppenhaver, D. W. Niesel, G. R. Klimpel, J. Stanton, and T. K. Hughes. 1991. The interferons: mechanisms of action and clinical applications. JAMA 266:1375.
27. Gutterman, J. U. 1994. Cytokine therapeutics: lessons from interferon α. Proc. Nail. Acad. Sci. USA 91:1198.
28. Sandberg, K., M. L. Eloranta, and I. L. Campbell. 1994. Expression of α/β interferons (α/β) and their relationship to IFN-α/β-induced genes in lymphocytic choriomeningitis. J. Virol. 68:7358.
29. Mittnacht, S., P. Straub, H. Kirchner, and H. Jacobsen. 1988. Interferon treatment inhibits onset of herpes simplex virus immediate-early transcription. Virology 179:487.
30. Daigle, J., and D. J. J. Carr. 1998. Androstenediol antagonizes herpes simples virus type 1-induced encephalitis through the augmentation of type 1 interferon production. J. Immunol. 160:3060.
31. Friedman, R. M. 1966. Effect of interferon treatment on interferon production. J. Immunol. 96:872.
32. Stewart, W. E. II, L. B. Grossner, and R. Z. Lockart Jr. 1971. Priming: a non antiviral function of interferon. J. Virol. 7:792.
33. Rosztoczy, I. 1986. Study of the in vivo priming effect of interferon in mice. J. Gen. Virol. 67:2731.
34. Fuchsberger, N., G. Karayianni-Vasconcelos, H.-L. Kauppinen, V. Hajnicka, and P. Kontsek. 1995. Priming with interferon-α1 or interferon-α2 enhances the production of both subtypes simultaneously. J. Interferon Cytokine Res. 15:637.
35. Feinstein, D. L., S. Akira, M. Narazaki, and T. Taga. 1992. Isolation of cDNA clones encoding rat glial fibrillary acidic protein: expression in astrocytes and Schwann cells. J. Neurosci. Res. 32:1.
36. Stewart, T. A., B. Hultgren, X. Huang, S. Pitts-Meek, J. Hully, and N. J. MacLachlan. 1993. Induction of type 1 diabetes by interferon-α in transgenic mice. Science 260:1942.
37. Wolff, J. A., R. W. Malone, P. Williams, W. Chong, G. Ascadi, A. Jani, and P. L. Felgner. 1990. Direct gene transfer into mouse muscle in vivo. Science 247:1465.
38. Lawson, C. M., W.-S. Yeow, C. M. Lee, and M. W. Beilharz. 1997. In vivo expression of an interferon-α gene by intramuscular injection of naked DNA. J. Interferon Cytokine Res. 17:255.
39. Yeow, W.-S., C. M. Lawson, and M. W. Beilharz. 1998. Antiviral activities of individual murine interferon a subtypes in vivo: intramuscular injection of interferon expression constructs reduces cytomegalovirus replication. J. Immunol. 160:2932.
40. Daheshia, M., N. Kuklin, S. Kanangat, E. Manickan, and B. T. Rouse. 1997. Suppression of ongoing ocular inflammatory disease by topical administration of plasmid encoding IL-10. J. Immunol. 159:1945.
41. Akwa, Y., D. E. Hassett, M.-L. Eloranta, K. Sandberg, E. Masliah, H. Powell, J. L. Whitton, F. E. Bloom, and I. L. Campbell. 1998. Transgenic expression of interferon-α in the central nervous system of mice protects against lethal neurotropic viral infection, but induces inflammation and neurodegeneration. J. Immunol. In press this issue.