Neuroprotective effect of interleukin-6 and IL6/IL6R chimera in the quinolinic acid rat model of Huntington's syndrome

European Journal of Neuroscience

Volumn 14, Issue 11, 2001, Pages 1753-1761

  Bensadoun, Jean Charles ^a   Pereira de Almeida, Luis ^a,c   Dréano, Michel ^b   Aebischer, Patrick ^a,d   Déglon, Nicole ^a  

^a Centre Hospitalier Universitaire Vaudois   (Switzerland)

^b Serono International SA   (Switzerland)

^c UNIVERSITY OF COIMBRA   (Portugal)

^d EPFL   (Switzerland)

Author keywords

Gene therapy; Lentiviral vector; Quinolinic acid lesion model

Indexed keywords

HYBRID PROTEIN; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; LENTIVIRUS VECTOR; QUINOLINIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; DRUG EFFECT; DRUG POTENCY; FEMALE; HUNTINGTON CHOREA; IMMUNOCOMPETENT CELL; IMMUNOHISTOCHEMISTRY; NEUROPROTECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TREATMENT OUTCOME;

ACETYLCHOLINE; ANIMALS; DISEASE MODELS, ANIMAL; FEMALE; GAMMA-AMINOBUTYRIC ACID; GENETIC VECTORS; HUNTINGTON DISEASE; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-6; NEOSTRIATUM; NEURONS; NEUROPROTECTIVE AGENTS; QUINOLINIC ACID; RATS; RATS, WISTAR; RECEPTORS, INTERLEUKIN-6; RECOMBINANT FUSION PROTEINS;

EID: 0035783942     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0953-816X.2001.01802.x     Document Type: Article

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