Nucleotides as immunomodulators in clinical nutrition

Current Opinion in Clinical Nutrition and Metabolic Care

Volumn 4, Issue 1, 2001, Pages 57-64

  Grimble, George K ^a   Westwood, Olwyn M ^a  

^a UNIVERSITY OF ROEHAMPTON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; DNA; GLUTAMINE; IMMUNOMODULATING AGENT; NUCLEOTIDE; PURINE DERIVATIVE; PYRIMIDINE DERIVATIVE; RNA;

ANIMAL CELL; ANIMAL TISSUE; BREAST MILK; CONVALESCENCE; DIET SUPPLEMENTATION; DIETARY INTAKE; DNA DETERMINATION; HEART MUSCLE CELL; IMMUNOCOMPETENT CELL; IMMUNOMODULATION; INFECTION SENSITIVITY; INTESTINE CELL; INTESTINE INJURY; NONHUMAN; NUCLEIC ACID SYNTHESIS; NUCLEOTIDE METABOLISM; NUTRITION; REPERFUSION INJURY; REVIEW; RNA ANALYSIS; SIGNAL TRANSDUCTION; WOUND HEALING;

ADJUVANTS, IMMUNOLOGIC; ADMINISTRATION, ORAL; ANIMALS; DIETARY SUPPLEMENTS; HOMEOSTASIS; HUMANS; INTESTINAL MUCOSA; INTESTINES; LIVER; NUCLEOTIDES; NUTRITION PHYSIOLOGY; PARENTERAL NUTRITION, TOTAL;

ANIMALIA;

EID: 0035744409     PISSN: 13631950     EISSN: None     Source Type: Journal    
DOI: 10.1097/00075197-200101000-00011     Document Type: Review

References (72)

1. Effect of administration of nucleosides and nucleotides on protein turnover and the hypoxic myocardium
2. Effects of dietary polyunsaturated fatty acids and nucleotides on tissue fatty acid profiles of rats with carbon tetrachloride-induced liver damage
3. Dietary nucleic acids promote a shift in Th1/Th2 balance toward Th1-dominant immunity
4. Dietary nucleotides can upregulate antigen-specific Th1 immune responses and suppress antigen-specific IgE responses in mice
5. Influence of dietary nucleotides on plasma immunoglobulin levels and lymphocyte subsets of preterm infants
6. Intravenous nucleosides and a nucleotide promote healing of small bowel ulcers in experimental enterocolitis
7. Dietary supplementation of nucleotides and arginine promotes healing of small bowel ulcers in experimental ulcerative ileitis
8. Nucleoside-nucleotide free diet protects rat colonic mucosa from damage induced by trinitrobenzene sulphonic acid
9. Dietary nucleosides and nucleotides reduce infection in dexamethasone immunosuppressed adult mice
10. Dietary nucleotide supplementation raises erythrocyte 2,3-diphosphoglycerate concentration in neonatal rats
11. Nucleotides and immunity
12. Methods for measuring tissue RNA turnover
13. Immunonutrition - Fact or fad
14. Immunonutrition in the critically ill: A systematic review of clinical outcome
15. Immunonutrition and surgical practice
16. The effect of the administration of nucleosides and nucleotides for parenteral use
17. The role of dietary nucleotides in neonatal and infant nutrition
18. Dietary nucleotides: Effects on the immune and gastrointestinal systems
19. Lessons learned from studies on immune-nutrition in postoperative patients
20. Nucleotides and intestine
21. Nucleotide supplementation and the growth of term small for gestational age infants
22. Methotrexate inhibits the first committed step of purine biosynthesis in mitogen-stimulated human T-lymphocytes: A metabolic basis for efficacy in rheumatoid arthritis?
23. Mycophenolic acid-induced GTP depletion also affects ATP and pyrimidine synthesis in mitogen-stimulated primary human T-lymphocytes
24. Metabolic consequences of adenosine deaminase deficiency in mice are associated with defects in alveogenesis, pulmonary inflammation, and airway obstruction
25. Function of murine adenosine deaminase in the gastrointestinal tract
26. Emerging roles of purinergic signaling in gastrointestinal epithelial secretion and hepatobiliary function
27. Adenine, the precursor of nucleic acids in intestinal cells is unable to synthesize purines de novo
28. Discrete roles of hepatocytes and nonparenchymal cells in uridine catabolism as a component of its homeostasis
29. Role of glutamine on the de novo purine nucleotide synthesis in Caco-2 cells
30. Metabolism of orally and intravenously administered purines in rats
31. The relationship between whole body RNA and protein turnover in critically-ill children
32. RNA turnover following head injury or liver transplantation in paediatric patients
33. Uric acid and renal disease
34. Nomenclature and classification of purinoceptors
35. Pharmacokinetics of intravenous ATP in cancer patients
36. Pharmacokinetics and tolerability of intravenous infusion of adenosine (SUNY4001) in healthy volunteers
37. Magnesium-adenosine triphosphate in the treatment of shock, ischemia, and sepsis
38. Adenosine 5′-triphosphate induced dilation of human coronary microvessels in vivo
39. Adenosine and cardioprotection during ischaemia and reperfusion: An overview
40. Trophic effects of purines in neurons and glial cells
41. Renal ischemia/reperfusion remotely improves myocardial energy metabolism during myocardial ischemia via adenosine receptors in rabbits: Effects of 'remote preconditioning'
42. Adenosine triphosphate: Established and potential clinical applications
43. Adenosine receptor agonists attenuate and adenosine receptor antagonists exacerbate opiate withdrawal signs
44. Limitation of stunning in dog myocardium by nucleoside and nucleotide mixture, OG-VI
45. The effect of a nucleotide-nucleoside solution on hepatic regeneration in rats after partial hepatectomy and in primary monolayer culture of hepatocytes
46. Significance of nucleosides and a nucleotide mixture on hepatic energy metabolism of 70% hepatectomised rabbits in postoperative phase
47. Effects of nucleosides and a nucleotide mixture on gut mucosal barrier function on parenteral nutrition in rats
48. +-dependent nucleotide transporter from rabbit intestine
49. Absorption and metabolism of adenine, adenosine-5′-monophosphate, adenosine and hypoxanthine by the isolated vascularly perfused rat small intestine
50. Nucleotide-free diet impairs T-helper cell functions in antibody production in response to T-dependent antigens in normal C57B1/6 mice
51. Nucleotide-free diet suppresses antigen-driven cytokine production by primed T cells: Effects of supplemental nucleotides and dietary fatty acids
52. An orally supplemented mononucleotide mixture prevents the decrease in T cell-dependent humoral immunity in C57BL/6 mice fed a nucleotide-free diet
53. Dietary nucleic acids and Th1/Th2 balance: A clue to cow's milk allergy?
54. Dietary nucleotides modulate antigen-specific type 1 and type 2 t-cell responses in young c57bl/6 mice
55. RNA/nucleotide enhances antibody production in vitro and is moderately mitogenic to murine spleen lymphocytes
56. Liver histology, blood biochemistry and RNA, DNA and subcellular protein composition of various skeletal muscles of rats with experimental cirrhosis: Implications for alcoholic muscle disease
57. Effect of dietary nucleotide supplementation on diarrhoeal disease in infants
58. Diet and faecal flora in the newborn: Nucleotides
59. Hepatic heterogeneity in the response to AMP studies in the bivascularly perfused rat liver
60. Actions of extracellular UTP and ATP in perfused rat liver. A comparative study
61. Adenosine inhibits IL-12 and TNF-alpha production via adenosine A2a receptor-dependent and independent mechanisms
62. Adenosine regulates tissue factor expression on endothelial cells
63. Adenosine inhibits lipopoly-saccharide-induced cardiac expression of tumor necrosis factor-alpha
64. Adenosine receptor agonists differentially regulate IL-10, TNF-alpha, and nitric oxide production in RAW 264.7 macrophages and in endotoxemic mice
65. Adenosine inhibits macrophage colony-stimulating factor-dependent proliferation of macrophages through the induction of p27kip-1 expression
66. Inhibition of human monocyte TNF production by adenosine receptor agonists
67. Nucleoside-nucleotide-free diet suppresses cytokine production and contact sensitivity responses in rats with trinitrobenzene sulphonic acid-induced colitis
68. Perioperative immunonutrition in patients undergoing cancer surgery: Results of a randomized double-blind phase 3 trial
69. The anti-catabolic effects of n-3 fatty acids
70. Modulation of inflammation and immunity by arginine supplements
71. Arginine metabolism: Nitric oxide and beyond