Adenosine inhibits macrophage colony-stimulating factor-dependent proliferation of macrophages through the induction of p27(kip-1) expression

Journal of Immunology

Volumn 163, Issue 8, 1999, Pages 4140-4149

  Xaus, Jordi ^a   Valledor, Annabel F ^a   Cardó, Marina ^a   Marquès, Laura ^a   Beleta, Jorge ^b   Palacios, José M ^b   Celada, Antonio ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b Laboratorios Almirall Prodesfarma SA Research Center ^*  (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

8 BROMO CYCLIC AMP; ADENOSINE A1 RECEPTOR; ADENOSINE A2A RECEPTOR; ADENOSINE A2B RECEPTOR; ADENOSINE A3 RECEPTOR; ADENOSINE DERIVATIVE; ADENOSINE RECEPTOR; ADENYLATE CYCLASE; COLONY STIMULATING FACTOR 1; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; FORSKOLIN; PROTEIN P27;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; ENZYME ACTIVATION; ENZYME INHIBITION; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; RECEPTOR BINDING; REGULATORY MECHANISM;

EID: 0032853298     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (78)

1. Abbas, A. K., A. H. Lichtman and J. S. Pober. 1991. Cells and tissues of the immune system. In Cellular and Molecular Immunology. W. B. Saunders, Philadelphia, pp. 13-15.
2. Celada, A. 1994. Células del sistema inmunitario: granulocitos y fagocitos mononucleares. In Immunología Básica. A. Celada, ed. Editorial LABOR S.A., Barcelona, Spain, pp. 61-94.
3. Valledor, A. F., F. E. Borras, M. Cullell-Young, and A. Celada. 1998. Transcription factors that regulate monocyte/macrophage differentiation. J. Leukocyte Biol. 63: 405.
4. Nathan, C. F. 1987. Secretory products of macrophages. J. Clin. Invest. 79:319.
5. Stanley, E. R., K. L. Berg, D. B. Einstein, P. S. W. Lee, F. J. Pixley, Y. Wang, and Y. G. Yeung. 1997. Biology and action of colony-stimulating factor 1. Mol. Reprod. Dev. 46:4.
6. Vairo, G., and J. A. Hamilton. 1991. Signalling through CSF receptors, Immunol. Today 12:361.
7. Hamilton, J. A. 1997. CSF-1 signal transduction. J. Leukocyte Biol. 62:145.
8. 1 progression by CSF-1. Mol. Reprod. Dev. 46:11.
9. Courtneidege, S. A., R. Dhand, D. Pilat, G. M. Twarmley, M. D. Waterfield, and M. F. Roussel. 1993. Activation of Src family kinases by colony stimulating factor-1, and their association with its receptor. EMBO J. 12:943.
10. Novak, U., A. G. Harpur, L. Paradiso, V. Kanagasundaram, A. Jaworowski, A. F. Wilks, and J. A. Hamilton. 1995 CSF-1 induced STAT1 and STAT3 activation is accompanied by phosphorylation of Tyk2 in macrophages and Tyk2 and JAK1 in fibroblasts. Blood 86:2948.
11. Novak, U., A. Mui, A. Miyajima, and L. Paradiso. 1996. Formation of STAT5 containing DNA binding complexes in response to colony stimulating factor 1 and platelet-derived growth factor. J. Biol. Chem. 271:26947.
12. Katayama, N., M. Nishikawa, N. Mirami, and S. Shirakawa. 1989. Putative involvement of protein kinase C in proliferation of human myeloid progenitor cells. Blood 73:123.
13. Yusoff, P., J. A. Hamilton, R. D. Nolan, and W. A. Phillips. 1994. Hematopoietic colony stimulating factors CSF-1 and GM-CSF increase phosphatidylinositol 3-kinase activity in murine bone marrow-derived macrophages. Growth Factors 10:181.
14. Roche, S., M. Koel, and S. A. Coutneidge. 1994. The phosphatidylinositol 3-kinase α is required for DNA synthesis induced by some, but not all, growth factors. Proc. Natl. Acad. Sci. USA 91:9185.
15. Büscher, D., R. A. Hipskind, S. Krautwald, T. Reimann, and M. Baccarini. 1995. Ras-dependent and -independent pathways target the mitogen-activated protein kinase network in macrophages. Mol. Cell Biol. 15:466.
16. Seger, R., and E. G. Krebs. 1995. The MAPK signaling cascade. FASEB J. 9:726.
17. Treisman, R. 1996. Regulation of transcription by MAP kinase cascades. Curr. Opin. Cell Biol. 8:205.
18. Pelech, S. L. 1993. Networking with protein kinases. Curr Biol. 3:513.
19. Charles, C. H., H. Sun, L. F. Lau, and N. K. Tonks. 1993. The growth factor-inducible immediate-early gene 3CH134 encodes a protein-tyrosine-phosphatase. Proc. Natl. Acad. Sci. USA 90:5292.
20. Keyse, S. M., and E. A. Emslie. 1992. Oxidative stress and heat shock induce a human gene encoding a protein-tyrosine phosphatase. Nature 359:644.
21. Sun, H., C. H. Charles, L. F. Lau, and N. K. Tonks. 1993. MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphalase that dephosphorylates MAP kinase in vivo. Cell 75:487.
22. Sun, H., N. K. Tonks, and D. Bar-Sagi. 1994. Inhibition of Ras-induced DNA synthesis by expression of the phosphatase MKP-1. Science 266:285.
23. 1 specific gene transcription and S-phase entry in fibroblasts. Oncogene 10:1895.
24. 1 phase progression: cyclin on cue. Cell 79:551.
25. 1 cyclins. Curr. Opin. Cell Biol. 6:842.
26. 1 cyclin-dependent kinases. Genes Dev. 9:1149.
27. Serrano, M., G. J. Hannon, and D. Beach. 1993. A new regulatory motif in cell cycle control causing specific inhibition of cyclin D/CDK4. Nature 366:704.
28. Xiong, Y., G. J. Hannon, H. Zhang, D. Casso, R. Kobayashi, and D. Beach. 1993. p21 is a universal inhibitor of cyclin kinases. Nature 366:710.
29. 1 cyclin/cdk protein kinase activity, is related to p21. Cell 78:67.
30. Sherr, C. J., and E. R. Stanley. 1990. Colony stimulating factor-1, in Peptide Growth Factors and Their Receptors. Springer-Verlag, Heidelberg, Germany.
31. 1 phase of the cell cycle. Cell 65:701.
32. Cooper, J. A., and P. Whyte. 1989. RB and the cell cycle: entrance or exit? Cell 58:1009.
33. Vogelstein, B., and K. W. Kinzler. 1992. p53 function and dysfunction. Cell 70:523.
34. Cobrinik, D., S. F. Dowdy, P. W. Hinds, S. Mittnacht, and R. A. Weinberg. 1992. The retinoblastoma protein and the regulation of cell cycling. Trends Biochem. Sci. 17:312.
35. Murray, A. 1994. Cell cycle checkpoints. Curr. Opin. Cell Biol. 6:872.
36. Van Belle, H., F. Goossens, and J. Wynants. 1987. Formation and release of purine catabolites during hypoperfusion, anoxia and ischemia. Am. J. Physiol. 252:H886.
37. Matherne, G. P., J. P. Headrick, S. D. Coleman, and R. M. Berne. 1990. Intersticial transudate purines in normoxic and hipoxic immature and mature rabbit hearts. Pediatr. Res. 28:348.
38. Cronstein, B. N. 1994. Adenosine, an endogenous anti-inflammatory agent. J. Appl. Physiol. 76:5.
39. Haskó, G., C. Szabó, Z. H. Németh, V. Kvetan, S. M. Pastores, and E. S. Vizi. 1996. Adenosine receptor agonist differentially regulate IL-10, TNF-α and nitricoxide production in Raw-264.7 macrophages and in endotoxemic mice. J. Immunol. 157:4634.
40. Dalziel, H. H., and D. P. Westfall. 1994. Receptors for adenine nucleolides and nucleosides: subclassification, distribution, and molecular characterization. Pharmacol. Rev. 46:449.
41. Libert, F., M. Parmentier, A. Lefort, C. Dinsart, J. Van Sande, C. Maenhaut, M. J. Simons, J. E. Dumont, and G. Vassart. 1989. Selective amplification and cloning of four new members of the G protein-coupled receptor family. Science 24:570.
42. 2-adenosine receptor subtype. Mol. Endocrinol. 6:384.
43. 3 adenosine receptor. Proc. Natl. Acad. Sci. USA 89:7432.
44. Mullet, D., R. H. Fertel, D. Kniss, and G. W. Cox. 1997. An increase in intracellular cyclic AMP modulates nitric oxide production in IFN-γ-trealed macrophages. J. Immunol. 158:897.
45. 3 adenosine receptors. J. Immunol. 156:3435.
46. Ritchie, P. K., B. L. Spangelo, D. K. Krzymowski, T. B. Rossiter, E. Kurth, and A. M. Judd. 1997. Adenosine increases interleukin 6 release and decreases tumor necrosis factor release from rat adrenal zona glomerulosa cells, ovarian cells, anterior pituitary cells, and peritoneal macrophages. Cytokine 9:187.
47. Le Moine, O., P. Stordeur, L. Schandené, A. Marchant, D. de Groote, M. Goldman, and J. Devière. 1996. Adenosine enhances IL-10 secretion by human monocyles. J. Immunol. 156:4408.
48. Celada, A., P. W. Gray, E. Rinderknecht, and R. D. Schreiber. 1984. Evidence for a γ-interferon receptor that regulates macrophage tumoricidal activity. J. Exp. Med. 160:55.
49. Kip1 CDK "inhibitors" are essential activators of cyclin D-dependent kinases in murine fibroblasts. EMBO J. 18:1571.
50. 49. Xiong, Y., T. Connolly, B. Futcher, and D. Beach. 1991. Human D-type cyclin. Cell 65:691.
51. 1 cyclins. Cell 71:323.
52. Torczynski, P., A. P. Bollon, and M. Fuke. 1983. The complete nucleotide sequence of the rat 18S ribosomal RNA gene and comparison with the respective yeast and frog genes. Nucleic Acids Res. 11:4879.
53. Celada, A., and R. A. Maki. 1992. Transforming growth factor-β enhances the M-CSF and GM-CSF-stimulated proliferation of macrophages. J. Immunol. 148:1102.
54. Celada, A., F. E. Borras, C. Soler, J. Lloberas, M. Klemsz, C. van Beveren, S. McKercher, and R. A. Maki. 1996. The transcription factor PU.I is involved in macrophage proliferation. J. Exp. Med. 184:61.
55. Hogquist, K. A., M. A. Nett, E. R. Unanue, and D. D. Chaplin. 1991. Interleukin 1 is processed and released during apoptosis. Proc. Natl. Acad. Sci. USA 88:8485.
56. Samuels, M. L., M. J. Weber, J. M. Bishop, and M. McMahon. 1993. Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an eslradiol-dependent human Raf-1 protein kinase. Mol Cell Biol. 13:6241.
57. Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156.
58. North, R. A., and E. A. Barnard. 1997. Nucleotide receptors. Curr. Opin. Neurobiol. 7:346.
59. 2B adenosine receptor expression in macrophages: a mechanism of macrophage deactivation. J. Immunol. 162:3607.
60. 3H]-NECA in rat strial membranes. Mol. Pharmacol. 29:331.
61. 3H]-2-chloroadenosine. Int. J. Biochem. 14:399.
62. 2 receptors. In Adenosine and Adenosine Receptors. M. Williams, ed. Humana, Clifton, NJ, pp. 57.
63. 3-selective adenosine agonists. J. Med. Chem. 37:636.
64. 2 receptors in rat brain. J. Pharmacol. Exp. Ther. 251:388.
65. 1 adenosine receptor antagonist. Life Sci. 40:555.
66. Van Calker, D., M. Muller, and B. Hamprecht. 1979. Adenosine regulates, via two different types of receptors, the accumulation of cyclic AMP in cultured brain cell. J. Neurochem. 33:999.
67. Gurden, M. F., J. Coates, F. Ellis, B. Evans, M. Foster, E. Hornby, I. Kennedy, D. P. Martin, P. Strong, C. J. Vardey, and A. Wheeldon. 1993. Functional characterization of three adenosine receptor types. Br. J. Pharmacol. 109:693.
68. Ciruela, F., C. Saura, E. I. Canela, J. Malloll, C. Lluis, and R. Franco. 1996. Adenosine deaminase affects ligard-induced signaling by interacting with adenosine receptors. FEBS Lett. 380:219.
69. Fredholm, B. B., M. P. Abbrachio, G. Burnstock, J. W. Daly, T. K. Harden, K. A. Jacobson, P. Leff, and M. Williams. 1994. Nomenclature and classification of purinoreceptors. Pharmacol. Rev. 46:143.
70. Cotter, T. G. 1992. Induction of apoptosis in cells of the immune system by cytotoxic stimuli. Semin. Immunol. 4:399.
71. 1 stage of the cell cycle and overrides constitutive c-myc expression. Mol. Cell Biol. 12:2351.
72. kip1) of cyclin-dependent kinase 4 activation. Cell 79:487.
73. Vairo, G., S. Argyrious, A. M. Bordun, G. Whitty, and J. A. Hamilton. 1990. Inhibition of the signaling pathways for macrophage proliferation by cyclic AMP: lack of effect on early responses to colony stimulating factor-1. J. Biol. Chem. 265:2692.
74. Baccarini, M., S. P. Dello, D. Buscher, A. Bartocci, and E. R. Stanley. 1992. IFN-γ/lipopolysaccharide activation of macrophages is associated with protein kinase C-dependent down-modulation of the colony-stimulating factor-1 receptor. J. Immunol. 149:2656.
75. Jaworowski, A., E. Christy, P. Yusoff, R. Byrne, and J. A. Hamilton. 1996. Differences in the kinetics of activation of protein kinases and ERK-1 in CSF- and LPS-stimulated macrophages. Biochem J. 320:1011.
76. Burgering, B. M. T., and J. L. Bos. 1995. Regulation of Ras-mediated signalling: more than one way to skin a cat. Trends Biochem. Sci. 20:18.
77. Wilson, N. J., A. Jaworowski., A. C. Ward, and J. A. Hamilton. 1998. cAMP enhances CSF-1-induced ERK activity and c-fos mRNA expression via a MEK-dependent and Ras-independent mechanism in macrophages. Biochem. Biophys. Kes. Commun. 244:475.
78. kip1, a cyclin dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals. Cell 78:59.