Sevoflurane potentiates and blocks GABA-induced currents through recombinant α1β2γ2 GABAA receptors: Implications for an enhanced GABAergic transmission

European Journal of Anaesthesiology

Volumn 18, Issue 6, 2001, Pages 377-383

  Hapfelmeier, G ^a,c   Schneck, H ^b   Kochs, E ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b Kreisklinik Ebersberg   (Germany)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Anaesthetic Action, channel block; Ligand Activated Ion Channels, GABAA receptor; Volatile Anaesthetics, sevoflurane

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; BICUCULLINE; PICROTOXIN; SEVOFLURANE;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DESENSITIZATION; DRUG EFFECT; DRUG MECHANISM; DRUG POTENTIATION; EMBRYO; GABAERGIC TRANSMISSION; HUMAN; HUMAN CELL; MINIMUM LUNG ALVEOLUS CONCENTRATION; PATCH CLAMP; RECEPTOR BLOCKING; SYNAPTIC TRANSMISSION;

ANESTHETICS, INHALATION; BICUCULLINE; CELL LINE; GABA ANTAGONISTS; GAMMA-AMINOBUTYRIC ACID; HUMANS; ION CHANNELS; KIDNEY; METHYL ETHERS; PICROTOXIN; RECEPTORS, GABA-A; SYNAPTIC TRANSMISSION;

EID: 0035741525     PISSN: 02650215     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0265-0215.2001.00848.x     Document Type: Article

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