Sevoflurane modulates both GABA(A) and GABA(B) receptors in area CA1 of rat hippocampus

British Journal of Anaesthesia

Volumn 78, Issue 1, 1997, Pages 60-65

  Hirota, K ^a   Roth, S H ^b  

^a UNIVERSITY OF TOYAMA   (Japan)

^b UNIVERSITY OF CALGARY   (Canada)

Author keywords

Anaesthetics volatile, sevoflurane; Brain, hippocampus; Rat; Receptors, amino acid

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; 4 AMINOBUTYRIC ACID A RECEPTOR STIMULATING AGENT; 4 AMINOBUTYRIC ACID B RECEPTOR; 4 AMINOBUTYRIC ACID B RECEPTOR BLOCKING AGENT; 4 AMINOBUTYRIC ACID B RECEPTOR STIMULATING AGENT; BACLOFEN; BICUCULLINE METHIODIDE; INHALATION ANESTHETIC AGENT; MUSCIMOL; PHACLOFEN; SEVOFLURANE; 4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; 4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT; ETHER DERIVATIVE;

ANIMAL TISSUE; ARTICLE; BRAIN SLICE; DRUG ANTAGONISM; DRUG POTENTIATION; HIPPOCAMPUS; MALE; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; ANIMAL; CULTURE TECHNIQUE; DRUG EFFECT; ELECTROSTIMULATION; METABOLISM; SPRAGUE DAWLEY RAT;

ANESTHETICS, INHALATION; ANIMALS; CULTURE TECHNIQUES; ELECTRIC STIMULATION; ETHERS; GABA AGONISTS; GABA ANTAGONISTS; HIPPOCAMPUS; MALE; METHYL ETHERS; PYRAMIDAL CELLS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; RECEPTORS, GABA-B;

EID: 0030615001     PISSN: 00070912     EISSN: None     Source Type: Journal    
DOI: 10.1093/bja/78.1.60     Document Type: Article

References (29)

1. Yang J, Zorumski CF. Effects of isoflurane on N-methyl-D-aspartate gated ion channels in cultured rat hippocampal neurons. Annals of the New York Academy of Sciences 1991; 625: 287-289.
2. Study RE. Isoflurane inhibits multiple voltage-gated calcium currents in hippocampal pyramidal neurons. Anesthesiology 1994; 81: 104-116.
3. MacIver MB, Roth SH. Inhalation anesthetics exhibit pathway-specific and differential actions on hippocampal synaptic responses in vitro. British Journal of Anaesthesia 1988; 60: 680-691.
4. Perouansky M, Baranov D, Salman M, Yaari Y. Effects of halothane on glutamate receptor-mediated excitatory postsynaptic currents. A patch-clamp study in adult mouse hippocampal slices. Anesthesiology 1995; 83: 109-119.
5. Nicoll RA. The effects of anaesthetics on synaptic excitation and inhibition in the olfactory bulb. Journal of Physiology (London) 1972; 223: 803-814.
6. McCormick DA. GABA as an inhibitory neurotransmitter in human cerebral cortex. Journal of Neurophysiology 1989; 62: 1018-1027.
7. Cheng S-C, Brunner EA. Inducing anesthesia with a GABA analog, THIP. Anesthesiology 1985; 63: 147-151.
8. A receptor subtypes: from pharmacology to molecular biology. FASEB Journal 1991; 5: 2916-2923.
9. B receptor pharmacology. Annual Review of Pharmacology and Toxicology 1993; 33: 109-147.
10. Nakahiro M, Yeh JZ, Brunner E, Narahashi T. General anesthetics modulate GABA receptor channel complex in rat dorsal ganglion neurons. FASEB Journal 1989; 3: 1850-1854.
11. - currents in cultured rat hippocampal neurones by three volatile anaesthetics. Journal of Physiology (London) 1992; 449: 279-293.
12. Wakamori M, Ikemoto Y, Akaike N. Effects of two volatile anesthetics and a volatile convulsant on the excitatory and inhibitory amino acid responses in dissociated CNS neurons of the rat. Journal of Neurophysiology 1991; 66: 2014-2021.
13. Yang J, Tsenberg KE, Zorumski CF. Volatile anesthetics gate a chloride current in postnatal rat hippocampal neurons. FASEB Journal 1992; 6: 914-918.
14. A receptors expressed by Xenopus oocytes: lack of involvement of intracellular calcium. Journal of Pharmacology and Experimental Therapeutics 1992; 263: 569-578.
15. Pearce RA, Stringer JL, Lothman EW. Effects of volatile anesthetics on synaptic transmission in rat hippocampus. Anesthesiology 1989; 71: 591-598.
16. Sawynok J, Labella FS. Naloxone antagonizes inhibitory and unmasks excitatory effects of baclofen. Journal of Pharmacy and Pharmacology 1981; 33: 597-599.
17. Wu J, Harata N, Akaike N. Sevoflurane-induced ionic current in acutely dissociated CA1pyramidal neurons of the rat hippocampus. Brain Research 1994; 645: 303-308.
18. Kerr DIB, Ong J, Prager RH, Gyther BD, Curtis DR. Phaclofen: a peripheral and central baclofen antagonist. Brain Research 1987; 405: 150-154.
19. MacIver MB, Roth SH. Enflurane-induced burst firing of hippocampal CA1 neurones. British Journal of Anaesthesia 1987; 59: 369-378.
20. Albertson TE, Tseng C-C, Joy RM. Propofol modification of evoked hippocampal dentate inhibition in urethaneanesthetized rats. Anesthesiology 1991; 75: 82-90.
21. Strum DP, Eger EI II. Partition coefficients for sevoflurane in human blood, saline, and olive oil. Anesthesia and Analgesia 1987; 66: 654-656.
22. Kendig JJ, Maclver MB, Roth SH. Anesthetic actions in the hippocampal formation. Annals of the New York Academy of Sciences 1991; 625: 37-53.
23. B receptors in the central nervous system. Nature (London) 1988; 332: 156-158.
24. Davies CH, Davies SN, Collingridge GL. Paired-pulse depression of monosynaptic GABA-mediated inhibitory postsynaptic responses in rat hippocampus. Journal of Physiology (London) 1990; 434: 513-531.
25. Mody I, Tanelian DL, MacIver MB. Halothane enhances tonic neuronal inhibition by elevating intracellular calcium. Brain Research 1991; 538: 319-323.
26. Yoshimura M, Higashi H, Fujita S, Shimoji K. Selective depression of hippocampal inhibitory postsynaptic potentials and spontaneous firing by volatile anesthetics. Brain Research 1985; 340: 363-368.
27. Nathan T, Lambert JDC. Depression of the fast IPSP underlies paired-pulse facilitation in area CA1 of the rat hippocampus. Journal of Neurophysiology 1991; 66: 1704-1715.
28. Cheng S-C, Brunner EA. A hypothetical model on the mechanism of anesthesia. Medical Hypotheses 1987; 23: 1-9.
29. A receptor structure. Journal of Neurochemistry 1993; 60: 1548-1553.