Myocardial depressant effects of sevoflurane: Mechanical and electrophysiologic actions in vitro

Anesthesiology

Volumn 84, Issue 5, 1996, Pages 1166-1176

  Park, Wyun Kon ^a   Pancrazio, Joseph J ^b   Suh, Chang Kook ^c   Lynch III, Carl ^b  

^a Yonsei University College of Medicine   (South Korea)

^b UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^c Inha University School of Medicine   (South Korea)

Author keywords

Anesthetics, volatile: sevoflurane; Heart: action potential; contractility; guinea pig; rapid cooling contracture; rat; Ions: calcium current

Indexed keywords

CALCIUM ION; POTASSIUM ION; SEVOFLURANE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CURRENT; CONTROLLED STUDY; DRUG EFFECT; FEMALE; GUINEA PIG; HEART DEPOLARIZATION; HEART ELECTROPHYSIOLOGY; HEART MUSCLE CONTRACTILITY; HEART MUSCLE POTENTIAL; IN VITRO STUDY; INHALATION ANESTHESIA; MUSCLE ISOMETRIC CONTRACTION; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; PRIORITY JOURNAL; RAT; SARCOPLASMIC RETICULUM;

ANESTHETICS, INHALATION; ANIMALS; CALCIUM; DEPRESSION, CHEMICAL; ETHERS; FEMALE; GUINEA PIGS; METHYL ETHERS; MYOCARDIAL CONTRACTION; PAPILLARY MUSCLES; POTASSIUM CHANNELS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 9244238120     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-199605000-00019     Document Type: Article

References (60)

1. Strum DP, Eger EI II: Partition coefficients for sevoflurane in human blood, saline, and olive oil. Anesth Analg 1987; 66:654-6
2. Wallin RF, Regan BM, Napoli MD, Stern IJ: Sevoflurane: A new inhalational anesthetic agent. Anesth Analg 1975; 54:758-66
3. Holaday DA, Smith FR: Clinical characteristics and biotransformation of sevoflurane in healthy human volunteers. ANESTHESIOLOGY 1981; 54:100-6
4. Manohar M, Parks C: Porcine systemic and regional organ blood flow during 1.0 and 1.5 minimum alveolar concentrations of sevoflurane anesthesia without and with 50% nitrous oxide. J Pharmacol Exp Ther 1984; 231:640-8
5. Frink EJ Jr, Malan TP, Atlas M, Dominguez LM, DiNardo JA, Brown BR Jr: Clinical comparison of sevoflurane and isoflurane in healthy patients. Anesth Analg 1992; 74:241-5
6. Kasuda H, Akazawa S, Shimizu R: The echocardiographic assessment of left ventricular performance during sevoflurane and halothane anesthesia. J Anesth 1990, 4:295-302
7. Kazama T, Ikeda K: Comparison of MAC and the rate of rise of alveolar concentration of sevoflurane with halothane and isoflurane in the dog. ANESTHESIOLOGY 1988; 68:435-7
8. Bernard JM, Wouters PF, Doursout MF, Florence B, Chelly JE, Merin RG: Effects of sevoflurane and isoflurane on cardiac and coronary dynamics in chronically instrumented dogs. ANESTHESIOLOGY 1990; 72:659-62
9. Lynch C III: Cellular Electrophysiology of the Heart, Clinical Cardiac Electrophysiology: Perioperative Considerations. Edited by Lynch C III. Philadelphia, JB Lippincott, 1994, pp 1-52
10. Hatakeyama N, Ito Y, Momose Y: Effects of sevoflurane, isoflurane, and halothane on mechanical and electrophysiologic properties of canine myocardium. Anesth Analg 1993; 7:1327-32
11. Hatakeyama N, Momose Y, Ito Y: Effects of sevoflurane on contractile responses and electrophysiologic properties in canine single cardiac myocytes. ANESTHESIOLOGY 1995; 82:559-65
12. Bosnjak ZJ, Supan FD, Rusch NJ: The effects of halothane, enflurane and isoflurane on calcium currents in isolated canine ventricular cells. ANESTHESIOLOGY 1991; 74:340-5
13. Lynch C III: Differential depression of myocardial contractility by volatile anesthetics in vitro: Comparison with uncouplers of excitation-contraction coupling. J Cardiovasc Pharmacol 1990; 15:655-65
14. Lynch C III: Differential depression of myocardial contractility by halothane and isoflurane in vitro. ANESTHESIOLOGY 1986; 64:620-31
15. Su JY, Bell JG: Intracellular mechanism of action of isoflurane and halothane on striated muscle of the rabbit. Anesth Analg 1986; 65:457-62
16. 2+ release channel of cardiac sarcoplasmic reticulum by volatile anesthetics. ANESTHESIOLOGY 1994; 81:459-69
17. Lynch C III, Frazer MJ: Anesthetic alteration of ryanodine binding by cardiac calcium release channels. Biochim Biophys Acta 1994; 1194:109-17
18. Reuter H, Scholz H: The regulation of the calcium conductance of cardiac muscle by adrenaline. J Physiol (Lond) 1977; 264:49-62
19. Repke DI, Katz AH: The stimulation of calcium transport in cardiac sarcoplasmic reticulum by adenosine 3′:5′-monophosphate-dependent protein kinase. J Biol Chem 1974; 249:6174-80
20. Fabiato A, Fabiato J: Relaxing and inotropic effects of cyclic AMP on skinned cardiac cells. Nature 1975; 253:556-8
21. Seibel K, Karema E, Takeya K, Reiter M: Effects of noradrenaline on an early and late component of the myocardial contraction. Naunyn-Schmiedebergs Arch Pharmacol 1978; 305:65-74
22. 2+ release. Am J Physiol 1991; 260: H785-95
23. Bridge JHB: Relationships between the sarcoplasmic reticulum and sarcolemmal calcium transport revealed by rapidly cooling rabbit ventricular muscle. J Gen Physiol 1986; 88:437-73
24. Park WK, Pancrazio JJ, Lynch C III: Mechanical and electrophysiologic effects of protamine on isolated ventricular myocardium: Evidence for calcium overload. Cardiovasc Res 1994; 28:505-14
25. Hamill OP, Marty A, Neher E, Sakmann B, Sigworth FJ: Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflugers Arch 1981; 391: 85-100
26. Armstrong CM, Bezanilla F: Charge movement associated with the opening and closing of activation gates of Na channels. J Gen Physiol 1974; 63:533-52
27. Pancrazio JJ: PCS: An IBM-compatible microcomputer program for the analysis and display of voltage-clamp data. Comput Meth Prog Biomed 1993; 40:175-80
28. Katoh T, Ikeda K: The minimum alveolar concentration (MAC) of sevoflurane in humans. ANESTHESIOLOGY 1987; 66:301-3
29. Feldman MD, Gwathmey JK, Phillips P, Schoen FJ, Morgan JP: Reversal of the force-frequency relationship in working myocardium from patients with end-stage heart failure. J Appl Cardiol 1988; 3: 272-83
30. Schouten VJA, ter Keurs HEDJ: The force-frequency relationship in rat myocardium. The influence of muscle dimensions. Pflugers Arch 1986; 407:14-7
31. 2+ channels in guinea-pig heart cells. J Physiol (Lond) 1992; 456:247-66
32. Pancrazio JJ: Halothane and isoflurane preferentially depress a component of calcium channel current which undergoes slow inactivation. J Physiol (Lond) (in press)
33. Baum VC, Wetzel GT, Klitzner TS: Effects of halothane and ketamine on activation and inactivation of myocardial calcium current. J Cardiovasc Pharmacol 1994; 23:799-805
34. Kemmotsu O, Hashimoto Y, Shimosato S: Inotropic effects of isoflurane on mechanics of contraction in isolated cat papillary muscles from normal and failing hearts. ANESTHESIOLOGY 1973; 39:470-7
35. Komai H, Rusy BF: Negative inotropic effects of isoflurane and halothane in rabbit papillary muscles. Anesth Analg 1987; 66:29-33
36. Housmans PE, Murat I: Comparative effects of halothane, enflurane, and isoflurane at equipotent anesthetic concentrations on isolated ventricular myocardium of the ferret. I. Contractility. ANESTHESIOLOGY 1988; 69:451-63
37. Harkin CP, Pagel PS, Kersten JR, Hettrick DA, Warltier DC: Direct negative inotropic and lusitropic effects of sevoflurane. ANESTHESIOLOGY 1994; 81:156-67
38. Kikura M, Ikeda K: Comparison of the effects of sevoflurane/nitrous oxide and enflurane/nitrous oxide on myocardial contractility in humans: Load-independent and noninvasive assessment with transesophageal echocardiography. ANESTHESIOLOGY 1993; 79:235-43
39. Lynch C III, Frazer MJ: Depressant effects of volatile anesthetics upon rat and amphibian ventricular myocardium: Insights into mechanisms of action. ANESTHESIOLOGY 1989; 70:511-22
40. Reiter M, Vierling W, Seibel K: Excitation-contraction coupling in rested-state contractions of guinea pig ventricular myocardium. Naunyn-Schmiedebergs Arch Pharmacol 1984; 325:159-69
41. Lewartowski B, Prokopczuk A, Pytkowski B: Effect of inhibitors of slow calcium current on rested state contraction of papillary muscles and the post rest contractions of atrial muscle of the cat and rabbit hearts. Pflugers Arch 1978; 377:167-75
42. Shattock MJ, Bers DM: Rat vs. rabbit ventricle: Ca flux and intracellular Na assessed by ion-selective microelectrodes. Am J Physiol 1989; 256:C813-22
43. Bassani JWM, Bassani RA, Bers DM: Relaxation in rabbit and rat cardiac cells: Species-dependent differences in cellular mechanisms. J Physiol (Lond) 1994; 476:279-93
44. Komai H, Redon D, Rusy BF: Effects of isoflurane and halothane on rapid cooling contractures in myocardial tissue. Am J Physiol 1989; 257:H1804-11
45. Kurihara S, Sakai T: Effects of rapid cooling on mechanical and electrical responses in ventricular muscle of guinea-pig. J Physiol (Lond) 1985; 361:361-78
46. Feher JJ, Rebeyka IM: Cooling and pH jump-induced calcium release from isolated cardiac sarcoplasmic reticulum. Am J Physiol 1994; 267:H962-9
47. Bers DM: SR Ca loading in cardiac muscle preparations based on rapid-cooling contractures. Am J Physiol 1989; 256:C109-20
48. Vitez TS, White PF, Eger EI, II: Effects of hypothermia on halothane MAC and isoflurane MAC in the rat. ANESTHESIOLOGY 1974; 41: 80-1
49. Eskinder H, Rusch NJ, Supan FD, Kampine JP, Bosnjak ZJ: The effects of volatile anesthetics on L-type and T-type calcium channel currents in canine Purkinje cells. ANESTHESIOLOGY 1991; 74:919-26
50. Lee KS, Marban E, Tsien RW: Inactivation of calcium channels in mammalian heart cells: Joint dependence on membrane potential and intracellular calcium. J Physiol (Lond) 1985; 364:395-411
51. Delmar M, Michaels DC, Jalife J: Slow recovery of excitability and the Wenckebach phenomenon in the single guinea pig ventricular myocyte. Circ Res 1989; 65:761-74
52. + current by halothane in single frog atrial cells. Eur J Pharmacol 1986; 126:293-5
53. + conductance of myocardium. J Pharmacol Exp Ther 1993; 265:358-65
54. + current: Differential sensitivity to block by class III antiarrhythmic agents. J Gen Physiol 1990; 96:195-215
55. + channel protein in mammalian cells and immunolocalization in guinea pig heart. Circ Res 1993; 73:968-73
56. Varnum MD, Busch AE, Bond CT, Maylie J, Adelman JP: The min K channel underlies the cardiac potassium current IKs and mediates species-specific responses to protein kinase C. Proc Natl Acad Sci U S A 1993; 90:11528-32
57. Zorn L, Kulkarni R, Anantharam V, Bayley H, Treistman SN: Halothane acts on many potassium channels including a minimal potassium channel. Neurosci Lett 1993; 161:81-4
58. Crumb WJ Jr., Wible B, Arnold DJ, Payne JP, Brown AM: Blockade of multiple human cardiac potassium currents by the antihistamine terfenadine: Possible mechanism for terfenadine-associated cardiotoxicity. Mol Pharmacol 1994; 47:181-90
59. Varró A, Nánási PP, Lathrop DA: Potassium currents in isolated human atrial and ventricular cardiocytes. Acta Physiol Scand 1993; 149:133-42
60. + currents in human ventricular cells. Biophys J 1996; A276