Muts recognition: Multiple mismatches and sequence context effects

Journal of Biosciences

Volumn 26, Issue 5, 2001, Pages 595-606

  Joshi, Amita ^a   Rao, Basuthkar J ^a  

^a TATA INSTITUTE OF FUNDAMENTAL RESEARCH   (India)

Author keywords

Mismatch; MutS; Sequence context

Indexed keywords

GENE PRODUCT; PROTEIN MUTS; UNCLASSIFIED DRUG;

PROTEIN;

ARTICLE; BASE MISPAIRING; BINDING AFFINITY; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DNA BINDING; DNA FOOTPRINTING; DNA HELIX; ENZYME BINDING; ESCHERICHIA COLI; GENE SEQUENCE; HYDROLYSIS; NONHUMAN; PROTEIN PURIFICATION; SEQUENCE ANALYSIS;

ADENOSINE TRIPHOSPHATASES; BACTERIAL PROTEINS; BASE PAIR MISMATCH; BASE SEQUENCE; DNA PRIMERS; DNA REPAIR; DNA-BINDING PROTEINS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; MUTS DNA MISMATCH-BINDING PROTEIN; NUCLEIC ACID HETERODUPLEXES; PROTEIN BINDING; PROTEIN CONFORMATION;

ESCHERICHIA COLI; PROKARYOTA;

EID: 0035696150     PISSN: 02505991     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02704758     Document Type: Article

References (45)

1. NMR solution structure of a DNA dodecamer containing GT mismatches
2. Structure, dynamics, and thermodynamics of mismatched DNA oligonucleotide duplexes d(CCCAGGG)2 and d(CCCTGGG)2
3. Single base mismatches in DNA long- and short-range structure probed by analysis of axis trajectory and local chemical reactivity
4. The contrasting structures of mismatched DNA sequences containing looped-out bases bulges and multiple mismatches (bubbles)
5. Interaction of MutS protein with the major and minor grooves of a heteroduplex DNA
6. Solution structure as a function of pH of two central mismatches C·T and C·C in the 29 to 39 K-ras gene sequence by nuclear magnetic resonance and molecular dynamics
7. Affinity of mismatch-binding protein MutS for heteroduplexes containing different mismatches
8. Structures of mismatched base pairs in DNA and their recognition by the Escherichia coli mismatch repair system
9. Solution structure of two mismatches A·A and T·T in the K-ras gene context by nuclear magnetic resonance and molecular dynamics
10. Flexibility of DNA
11. The structure of guanosine-thymidine mismatches in B-DNA at 2·5-A resolution
12. Replication errors: Cha(lle)nging the genome
13. Mismatch-containing oligonucleotide duplexes bound by the E. coli mutS-encoded protein
14. ATP-hydrolysis-dependent conformational switch modulates the stability of MutS-mismatch complexes
15. Repair of a mismatch is influenced by the base composition of the surrounding nucleotide sequence
16. Detection of localized DNA flexibility
17. Non-Watson-Crick base pairs modulate homologous alignments in RecA pairing reactions
18. Pyrimidine·pyrimidine base pair mismatches in DNA. A nuclear magnetic resonance study of T·T pairing at neutral pH and C·C pairing at acidic pH in dodecanucleotide duplexes
19. Biochemistry and genetics of eukaryotic mismatch repair
20. Eukaryotic DNA mismatch repair
21. The crystal structure of DNA mismatch repair protein MutS binding to a G x T mismatch
22. Properties of multiple G·A mismatches in stable oligonucleotide duplexes
23. Conformational flexibility in DNA duplexes containing single G·G mismatches
24. Reaction of diethyl pyrocarbonate with nucleic acid components. Adenosine
25. 2-terminal region of Taq MutS protein to the major groove of a heteroduplex DNA
26. Recognition of DNA alterations by the mismatch repair system
27. Damage increases the flexibility of duplex DNA
28. Flexibility and curvature of duplex DNA containing mismatched sites as a function of temperature
29. Mismatch repair in replication fidelity, genetic recombination, and cancer biology
30. DNA repair mechanisms for the recognition and removal of damaged DNA bases
31. Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA
32. Repair of DNA hetero-duplexes containing small heterologous sequences in Escherichia coli
33. Deoxyguanosine-deoxyadenosine pairing in the d(C-G-A-G-A-AT-T-C-G-C-G duplex: Conformation and dynamics at and adjacent to the dG X dA mismatch site
34. Deoxyadenosine-deoxycytidine pairing in the d(C-G-C-G-A-A-T-T-C-A-C-G) duplex: Conformation and dynamics at and adjacent to the dA X dC mismatch site
35. Dynamics of DNA duplexes containing internal G·T G·A A·C and T·C pairs: Hydrogen exchange at and adjacent to mismatch sites
36. DNA lesions. A thermodynamic perspective
37. DNA repair: Models for damage and mismatch recognition
38. The barrier to recombination between Escherichia coli and Salmonella typhimurium is disrupted in mismatch repair mutants
39. DNA mismatch repair: MutS structures bound to mismatches
40. Escherichia coli mutS-encoded protein binds to mismatched DNA base pairs
41. Mispair specificity of methyl-directed DNA mismatch correction in vitro
42. Reaction of diethyl pyrocarbonate with nucleic acid components Bases and nucleosides derived from guanine, cytosine, and uracil
43. Mismatches in DNA double strands: Thermodynamic parameters and their correlation to repair efficiencies
44. Role of MutS ATPase activity in MutS, L-dependent block of in vitro strand transfer
45. The locus of sequence-directed and protein-induced DNA bending