Corticosterone controls interleukin-1β expression and sickness behavior in the rat

Journal of Neuroendocrinology

Volumn 8, Issue 2, 1996, Pages 129-135

  Pezeshki, Gita ^a   Pohl, Thomas ^a   Schöbitz, Bernd ^a  

^a MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

Author keywords

Cytokines; Fever; Glucocorticoid; Radiotelemetry

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CORTICOSTERONE; INTERLEUKIN 1BETA; MESSENGER RNA;

ADIPSIA; ADRENALECTOMY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANOREXIA; ARTICLE; BODY TEMPERATURE; CONTROLLED STUDY; FEVER; FLUID INTAKE; FOOD INTAKE; ILLNESS BEHAVIOR; LOCOMOTION; MALE; NONHUMAN; PHYSICAL ACTIVITY; PRIORITY JOURNAL; RAT; SUBCUTANEOUS DRUG ADMINISTRATION;

ADRENAL GLANDS; ADRENALECTOMY; ANIMALS; BEHAVIOR, ANIMAL; BLOTTING, NORTHERN; BODY TEMPERATURE; CORTICOSTERONE; DRINKING; EATING; INTERLEUKIN-1; LIPOPOLYSACCHARIDES; MALE; MOTOR ACTIVITY; RATS; RATS, WISTAR; RNA, MESSENGER; SPLEEN;

EID: 0029670130     PISSN: 09538194     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2826.1996.tb00833.x     Document Type: Article

References (36)

1. Hart BL. (1988). Biological basis of the behavior of sick animals. Neurosci Biobehav Rev. 12: 123-137.
2. Kent S, Bluthe R-M, Kelley KW, Dantzer R. (1992). Sickness behaviour as a new target for drug development. Trends Pharmacol Sci. 13: 24-28.
3. Schöbitz B, Reul JMHM, Holsboer F. (1994). The role of the hypothalamic-pituitary-adrenocortical system during inflammatory conditions. Critical Rev Neurobiol. 8: 263-291.
4. Kluger MJ. (1991). Fever: Role of pyrogens and cryogens. Physiol Rev. 71: 93-127.
5. Bluthe R-M, Dantzer R. (1992). Chronic intracerebral infusions of vasopressin and vasopressin antagonist modulate behavioral effects of interleukin-1 in rat. Brain Res Bull. 29: 897-900.
6. Willies GH, Woolf CJ. (1980). The site of action of corticosteroid antipyresis in the rabbit. J Physiol. 300: 1-6.
7. Carey F, Forder R, Edge MD, Greene AR, Horan MA, Strijbos PJLM, Rothwell NJ. (1990). Lipocortin 1 fragment modifies pyrogenic actions of cytokines in rats. Am J Physiol. 259: R266-R269.
8. Schöbitz B, Holsboer F, Sutanto W, Groß G, Schönbaum E, de Kloet ER. (1994). Corticosterone modulates interleukin-evoked fever in the rat. Neuroendocrinology. 59: 387-395.
9. Plata-Salaman CR. (1991) Dexamethasone inhibits food intake suppression induced by low doses of interleukin-1 beta intracerebroventricularly. Brain Res Bull. 27. 737-738.
10. Toth LA, Gardiner TW, Krueger JM. (1992). Modulation of sleep by cortisone in normal and bacterially infected rabbits. Am J Physiol. 263: R1339-R1344.
11. Besedovsky HO, delRey A, Sorkin E, Dinarello CA. (1987). Immunoregulatory feedback between interleukin-1 and glucocorticoid hormones. Science. 233: 652-654.
12. Berkenbosch F, Van Oers J, delRey A, Tilders F, Besedovsky HO. (1987). Corticotropin-releasing factor-producing neurons in the rat activated by interleukin-1. Science. 238: 524-526.
13. Besedovsky HO, delRey A. (1992). Immune-neuroendocrine networks. Front Neuroendocrinol. 13: 61-94
14. Schöbitz B, de Kloet ER, Holsboer F. (1994). Gene expression and function of interleukin 1, interleukin 6 and tumor necrosis factor in the brain. Prog Neurobiol. 44: 397-432.
15. Munck A, Guyre PM, Holbrook NJ. (1984) Physiological functions of glucocorticoids in stress and their relation to pharmacological actions. Endocr Rev. 5: 25-44.
16. Coelho MM, Souza GEP, Pela IR. (1992) Endotoxin-induced fever is modulated by endogenous glucocorticoids in rats. Am J Physiol. 263: R423-R427.
17. Morrow LE, McClellan JL, Conn CA, Kluger MJ. (1993). Glucocorticoids alter fever and IL-6 responses to psychological stress and to lipopolysaccharides. Am J Physiol. 264. R1010-1016.
18. Schöbitz B, van den Dobbelsteen M, Sutanto W, Holsboer F, de Kloet ER. (1993). Regulation of IL6 gene expression in rat. Endocrinology. 132: 1569-1576.
19. McClellan JL, Klir JJ, Morrow LE, Kluger MJ. (1994) Central effects of glucocorticoid receptor antagonist RU-38486 on lipopolysaccharide and stress-induced fever. Am J Physiol. 267: R705-711.
20. Chomczynski P, Sacchi N. (1987). Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem. 162: 156-159.
21. Sambrook J, Fritsch EF, Maniatis T (1989). Molecular cloning, a Laboratory Manual. 7.39-7.52. Cold Spring Harbour Laboratory Press, Cold Spring, New York
22. Bandtlow CE, Meyer M, Lindholm D, Spranger M, Heumann R, Thoenen H. (1991). Regional and cellular codistribution of interleukin 1 beta and nerve growth factor mRNA in the adult rat brain: Possible relationship to the regulation of nerve growth factor synthesis. J Cell Biol. 111: 1701-1711
23. Forth Ph, Marty L, Piechaczyk M, Sabrouty SE, Dani C, Jeanteur P, Blanchard JM. (1985). Various rat adult tissues express only one major mRNA species from glyceraldehyde-3-phosphate dehydrogenase multigenic family. Nucl Acid Res. 13: 1431-1442.
24. Garcia J, Hankins WG, Rusiniak KW. (1974). Behavioral regulation of the milieu interne in man and rat. Science. 185: 824-831.
25. Dantzer R, Bluthe R-M, Kelley KW. (1991). Androgen-dependent vasopressinergic neurotransmission attenuates interleukin-1 induced sickness behavior. Brain Res. 557. 115-120.
26. Dantzer R, Satinoff E, Kelley KW. (1987). Cyclosporine and alpha-interferon do not attenuate morphine withdrawal in rats but do impair thermoregulation. Physiol Behav. 39: 593-598.
27. Leshner AI (1971). The adrenals and the regulatory nature of running wheel activity. Physiol Behav. 6: 551-558.
28. Hamelink CR, Curie PJ, Chambers JW, Castonguay TW, Coscina D. (1994). Corticosterone-responsive and -unresponsive metabolic characteristics in adrenalectomized rats. Am J Physiol. 267: R799-R804.
29. Snyder DS, Unanue ER. (1982). Corticosteroids inhibit murine macrophage Ia expression and interleukin 1 production. J Immunol. 129: 1803-1805.
30. Lee SW, Tsou AP, Chan H, Thomas J, Petrie K, Eugui EM, Allison AC (1988). Glucocorticoid selectively inhibit the transcription of the interleukin 1β mRNA. Proc Natl Acad Sci USA. 85: 1204-1208.
31. Baybutt HN, Holsboer F. (1990). Inhibition of macrophage differentiation and function by cortisol. Endocrinology. 127: 476-480.
32. Reul JMHM, de Kloet ER. (1985). Two receptor systems for corticosterone in rat brain: microdistribution and differential occupation. Endocrinology. 117: 2505-2511.
33. Schöbitz B, Sutanto W, Carey MP, Holsboer F, de Kloet ER. (1994). Endotoxin and interleukin 1 decrease the affinity of hippocampal mineralocorticoid receptor (type I) in parallel to activation of the hypothalamic-pituitary-adrenal axis Neuroendocrinology. 60: 124-133.
34. Bluthe R-M, Dantzer R, Kelley KW. (1989). CRF is not involved in the behavioural effects of peripherally injected interleukin-1 in the rat. Neurosci Res Commun. 5: 149-154.
35. Rothwell NJ. (1989). CRF is involved in the pyrogenic and thermogenic effects of interleukin 1β in the rat. Am J Physiol. 256: E111-E115.
36. Spodaro F, Dunn AJ. (1990). Intracerebroventricular administration of interleukin-1 to mice alters investigation of stimuli in a novel environment. Brain Behav Immun. 4: 308-322.