Diverse effects of chronic treatment with losartan, fosinopril, and amlodipine on apoptosis, angiotensin II in the left ventricle of hypertensive rats

International Journal of Cardiology

Volumn 81, Issue 2-3, 2001, Pages 123-129

  Yu, Guolong ^a   Liang, Xiaoqiu ^a   Xie, Xiumei ^a   Su, Ming ^a   Zhao, Suiping ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Angiotensin II; Apoptosis; Cardiac hypertrophy; Drug therapy

Indexed keywords

AMLODIPINE; ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; CALCIUM CHANNEL BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; FOSINOPRIL; LOSARTAN; PLACEBO;

ANGIOTENSIN BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG EFFECT; HEART HYPERTROPHY; HEART LEFT VENTRICLE; HEART MUSCLE CELL; HEART PROTECTION; HEART WEIGHT; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SPONTANEOUSLY HYPERTENSIVE RAT; SYSTOLIC BLOOD PRESSURE;

AMLODIPINE; ANGIOTENSIN II; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; ANTIHYPERTENSIVE AGENTS; APOPTOSIS; BLOOD PRESSURE; CHINA; DISEASE MODELS, ANIMAL; FOSINOPRIL; HEART VENTRICLES; HYPERTROPHY, LEFT VENTRICULAR; LOSARTAN; MODELS, CARDIOVASCULAR; MYOCARDIUM; RANDOM ALLOCATION; RATS; RATS, INBRED SHR; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTORS, ANGIOTENSIN;

EID: 0035668113     PISSN: 01675273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-5273(01)00539-3     Document Type: Article

References (28)

1. Apoptosis in myocytes in end-stage heart failure
2. Apoptosis in human acute myocardial infarction
3. Apoptosis in pressure-overload induced heart hypertrophy in the rat
4. Increased cardiomyocyte apoptosis during the transition to heart failure in the spontaneously hypertensive rat
5. Apoptotic and necrotic myocyte cell deaths are independent contributing variables of infarct size in rats
6. Evidence of cardiocyte apoptosis in myocardium of dogs with chronic heart failure
7. Hypothesis: Apoptosis may be a mechanism for the transition to heart failure with chronic pressure overload
8. Myocyte apoptosis and heart failure
9. Chronic effects of enalapril and amlodipine on cardiac remodeling in cardiomyopathic hamster hearts
10. Overexpression of bax protein and enhanced apoptosis in the left ventricle of spontaneously hypertensive rats: Effects of AT1 blockade with losartan
11. Cardiovascular effects of combination of perindopril, candesartan, and amlodipine in hypertensive rats
12. Cardiac hypertensive rat
13. Early captopril treatment prevents hypertrophy dependent gene expression in hearts of SHR
14. Cardiac structural remodeling after treatment of spontaneously hypertensive rats with nifedipine or nisoldipine
15. Stretch-induced programmed myocyte cell death
16. Cardiomyocyte apoptosis and cardiac angiotensin-converting enzyme in spontaneously hypertensive rats
17. Cardiac action of angiotensin II: Role of an intracardiac rennin-angiotensin system
18. Apoptosis: Basic mechanisms and implications for cardiovascular diseases
19. Angiotensin II type 2 receptor mediates programmed cell death
20. Angiotensin II activates programmed myocyte cell death in vitro
21. Collagen metabolism in cultured adult rat cardiac fibroblasts: Response to angiotensin II and aldosterone
22. Increased apoptosis in the heart of genetic hypertension, associated with increased fibroblasts
23. Caspase activation and mitochondrial cytochrome C release during hypoxia-mediated apoptosis of adult ventricular myocytes
24. Chronic AT1 receptor blockade and angiotensin-converting enzyme inhibition in (CHF 146) cardiomyopathic hamsters: Effects on cardiac hypertrophy and survival
25. Cardiomyocyte apoptosis and cardiac angiotensin-converting enzyme in spontaneously hypertensive rats
26. Recent insight into therapy of congestive heart failure: Focus on ACE inhibition and angiotensin-II antagonism
27. Effects of anglotensin-converting enzyme inhibition and angiotensin II AT1 receptor antagonism on cardiac parameters in left ventricular hypertrophy
28. Role of bradykinin in the reduction of left ventricular hypertrophy induced by angiotensin-converting enzyme inhibitors in spontaneously hypertensive rats