Structure-function analysis of fission yeast Hus1-Rad1-Rad9 checkpoint complex

Molecular Biology of the Cell

Volumn 12, Issue 12, 2001, Pages 3744-3758

  Kaur, R ^a   Kostrub, C F ^a   Enoch, T ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLINE; FUNGAL PROTEIN; PROTEIN HUS1; PROTEIN RAD1; PROTEIN RAD9; UNCLASSIFIED DRUG;

ALLELE; ARTICLE; CELL CYCLE; COMPLEX FORMATION; CONTROLLED STUDY; GENE MUTATION; MOLECULAR EVOLUTION; MOLECULAR MODEL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STRUCTURE; STRUCTURE ACTIVITY RELATION; YEAST;

FUNGI; SCHIZOSACCHAROMYCES POMBE;

EID: 0035658296     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.12.12.3744     Document Type: Article

References (48)

1. Conserved domains in DNA repair proteins and evolution of repair systems
2. Schizosaccharomyces pombe proliferating cell nuclear antigen mutations affect DNA polymerase delta processivity
3. A mutational analysis of the yeast proliferating cell nuclear antigen indicates distinct roles in DNA replication and DNA repair
4. TATA box mutations in the Schizosaccharomyces pombe nmt1 promoter affect transcription efficiency but not the transcription start point or thiamine repressibility
5. The Schizosaccharomyces pombe rad3 checkpoint gene
6. + cell cycle checkpoint control gene
7. DNA replication checkpoint control
8. Reconstitution and molecular analysis of the hRad9-hHus1-hRad1 (9-1-1) DNA damage-responsive checkpoint complex
9. HDAC1, a histone deacetylase, forms a complex with Hus1 and Rad9, two G2/M checkpoint Rad proteins
10. Characterization of Schizosaccharomyces pombe Hus1: A PCNA-related protein that associates with Rad1 and Rad9
11. A simple and efficient procedure for transformation of yeasts
12. Cell cycle control and cancer
13. Checkpoints: Controls that ensure the order of cell cycle events
14. Mutual correction of faulty PCNA subunits in temperature-sensitive lethal mus209 mutants of Drosophila melanogaster
15. Functional inactivation of genes by dominant negative mutations
16. DNA damage and cell cycle control in Schizosaccharomyces pombe
17. Tyrosine 114 is essential for the trimeric structure and the functional activities of human proliferating cell nuclear antigen
18. +
19. PCNA: Structure, functions and interactions
20. Protein-PCNA interactions: A DNA-scanning mechanism?
21. The C-terminal region of Schizosaccaromyces pombe proliferating cell nuclear antigen is essential for DNA polymerase activity
22. Role of a complex containing Rad17, Mec3, and Ddc1 in the yeast DNA damage checkpoint pathway
23. +, a fission yeast gene required for S-M and DNA damage checkpoints
24. Hus1p, a conserved fission yeast checkpoint protein, interacts with Rad1p and is phosphorylated in response to DNA damage
25. Use of gap repair in fission yeast to obtain novel alleles of specific genes
26. Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA
27. + checkpoint control gene
28. nmt1 of fission yeast. A highly transcribed gene completely repressed by thiamine
29. Molecular genetic analysis of fission yeast Schizosaccharomyces pombe
30. Clamping down on clamps and clamp loaders - The eukaryotic replication factor C
31. Rfc5, in cooperation with Rad24, controls DNA damage checkpoints throughout the cell cycle in Saccharomyces cerevisiae
32. Cell cycle checkpoints, chromosome stability and the progression of cancer
33. The REC1 gene of Ustilago maydis, which encodes a 3′->5′ exonuclease, couples DNA repair and completion of DNA synthesis to a mitotic checkpoint
34. + checkpoint gene encodes an exonuclease
35. The human checkpoint protein hRad17 interacts with the PCNA-like proteins hRad1, hHus1, and hRad9
36. Feedback controls and G2 checkpoints: Fission yeast as a model system
37. Replication factor C3 of Schizosaccharomyces pombe, a small subunit of replication factor C complex, plays a role in both replication and damage checkpoints
38. The human G2 checkpoint control protein hRAD9 is a nuclear phosphoprotein that forms complexes with hRAD1 and hHUS1
39. S-phase and DNA-damage checkpoints: A tale of two yeasts
40. A sliding clamp model for the Rad1 family of cell cycle checkpoint proteins
41. PCNA, a multifunctional ring on DNA
42. Structure-based predictions of Rad1, Rad9, Hus1 and Rad17 participation in sliding clamp and clamp-loading complexes
43. Human homologs of Schizosaccharomyces pombe Rad1, Hus1, and Rad9 form a DNA damageresponsive protein complex
44. DNA damage checkpoints update: Guetting molecular
45. + cell cycle checkpoint gene
46. Protein-PCNA interactions: A DNA-scanning mechanism?
47. The crystal structure of an unusual processivity factor, herpes simplex virus UL42, bound to the C terminus of its cognate polymerase