What can we teach Drosophila? What can they teach us?

Trends in Genetics

Volumn 17, Issue 12, 2001, Pages 719-726

  Waddell, Scott ^a   Quinn, William G ^b  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; CHEMICAL MUTAGEN; CYCLIC AMP; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN;

ANIMAL BEHAVIOR; ATTENTION; BRAIN REGION; COGNITION; DROSOPHILA; ENHANCER REGION; GENE EXPRESSION; GENE FUNCTION; GENE MUTATION; LEARNING; MEMORY; MOLECULAR CLONING; MOLECULAR GENETICS; MUTAGENESIS; NONHUMAN; OLFACTORY SYSTEM; PRIORITY JOURNAL; REVIEW; SECOND MESSENGER; SLEEP; TEMPERATURE SENSITIVE MUTANT; TISSUE SPECIFICITY; TRANSGENE; TRANSPOSON; VISION;

ANIMALS; ATTENTION; CIRCADIAN RHYTHM; CYCLIC AMP; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DROSOPHILA; GENETICS, BEHAVIORAL; LEARNING; MEMORY; MODELS, BIOLOGICAL; MUSHROOM BODIES; MUTATION; SENSATION;

ANIMALIA; BASIDIOMYCOTA; DROSOPHILA MELANOGASTER; INSECTA;

EID: 0035576875     PISSN: 01689525     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-9525(01)02526-4     Document Type: Review

References (81)

1. Conditioned behavior in Drosophila melanogaster
2. Classical conditioning and retention in normal and mutant Drosophila melanogaster
3. Reward learning in normal and mutant Drosophila
4. Basic organization of operant behavior as revealed in Drosophila flight orientation
5. Behavioral manipulation of retrieval in a spatial memory task for Drosophila melanogaster
6. Dunce, a mutant of Drosophila deficient in learning
7. Loss of calcium/calmodulin responsiveness in adenylate cyclase of rutabaga, a Drosophila learning mutant
8. The Drosophila memory mutant amnesiac
9. Radish, a Drosophila mutant deficient in consolidated memory
10. Deficient protein kinase C activity in turnip, a Drosophila learning mutant
11. The Drosophila mutation turnip has pleiotropic behavioral effects and does not specifically affect learning
12. Genetic dissection of consolidated memory in Drosophila
13. Defect in cyclic AMP phosphodiesterase due to the dunce mutation of learning in Drosophila melanogaster
14. Molecular analysis of cDNA clones and the corresponding genomic coding sequences of the Drosophila dunce+ gene, the structural gene for cAMP phosphodiesterase
15. +/Calmodulin-responsive adenylyl cyclase
16. The cyclic AMP phosphodiesterase encoded by the Drosophila dunce gene is concentrated in the mushroom body neuropil
17. Preferential expression of the Drosophila rutabaga gene in mushroom bodies, neural centers for learning in insects
18. Associative odor learning in Drosophila is abolished by chemical ablation of mushroom bodies
19. Drosophila mushroom body mutants are deficient in olfactory learning
20. Drosophila mushroom bodies are dispensable for visual, tactile, and motor learning
21. Associative learning disrupted by impaired Gs signaling in Drosophila mushroom bodies
22. Calmodulin-regulated adenylyl cyclases and neuromodulation
23. Localization of a short-term memory in Drosophila
24. A neuropeptide gene defined by the Drosophila memory mutant amnesiac
25. Ethanol intoxication in Drosophila: Genetic and pharmacological evidence for regulation by the cAMP signaling pathway
26. The amnesiac gene product is expressed in two neurons in the Drosophila brain that are critical for memory
27. Genetic dissection of memory formation in Drosophila melanogaster
28. Tripartite mushroom body architecture revealed by antigenic markers
29. Preferential expression in mushroom bodies of the catalytic subunit of protein kinase A and its role in learning and memory
30. cAMP-dependent protein kinase and the disruption of learning in transgenic flies
31. Defective learning in mutants of the Drosophila gene for a regulatory subunit of cAMP-dependent protein kinase
32. Effects of a conditional Drosophila PKA mutant on olfactory learning and memory
33. Prolonged activation of cAMP-dependent protein kinase during conditioning induces long-term memory in honeybees
34. Induction of a dominant negative CREB transgene specifically blocks long-term memory in Drosophila
35. CREB as a memory modulator: Induced expression of a dCREB2 activator isoform enhances long-term memory in Drosophila
36. Genetic dissection of structural and functional components of synaptic plasticity. III. CREB is necessary for presynaptic functional plasticity
37. Latheo, a new gene involved in associative learning and memory in Drosophila melanogaster, identified from P element mutagenesis
38. Nalyot, a mutation of the Drosophila myb-related Adf1 transcription factor, disrupts synapse formation and olfactory memory
39. Molecular cloning of linotte in Drosophila: A novel gene that functions in adults during associative learning
40. Identification of linotte, a new gene affecting learning and memory in Drosophila melanogaster
41. Latheo encodes a subunit of the origin recognition complex and disrupts neuronal proliferation and adult olfactory memory when mutant
42. Latheo, a Drosophila gene involved in learning, regulates functional synaptic plasticity
43. The receptor tyrosine kinase gene linotte is required for neuronal pathway selection in the Drosophila mushroom bodies
44. The Drosophila putative kinase linotte (derailed) prevents central brain axons from converging on a newly described interhemispheric ring
45. Olfactory learning deficits in mutants for leonardo, a Drosophila gene encoding a 14-3-3 protein
46. Integrin-mediated short-term memory in Drosophila
47. Drosophila fasciclinII is required for the formation of odor memories and for normal sensitivity to alcohol
48. 14-3-3 Proteins: Structure, function, and regulation
49. Leonardo, a Drosophila 14-3-3 protein involved in learning, regulates presynaptic function
50. A dynamically regulated 14-3-3, Slob, and Slowpoke potassium channel complex in Drosophila presynaptic nerve terminals
51. Integrin-mediated regulation of synaptic morphology, transmission, and plasticity
52. Cell adhesion molecules, CREB, and the formation of new synaptic connections
53. Genetic dissection of structural and functional components of synaptic plasticity. II. Fasciclin II controls presynaptic structural plasticity
54. Activity-dependent functional and developmental plasticity of Drosophila neurons
55. Role of cAMP cascade in synaptic stability and plasticity: Ultrastructural and physiological analyses of individual synaptic boutons in Drosophila memory mutants
56. A gain-of-function screen for genes controlling motor axon guidance and synaptogenesis in Drosophila
57. Conditional rescue of the dunce learning/memory and female fertility defects with Drosophila or rat transgenes
58. A neurofibromatosis-1-regulated pathway is required for learning in Drosophila
59. Developmental expression of an amn(+) transgene rescues the mutant memory defect of amnesiac adults
60. Conditioning of leg position in normal and mutant Drosophila
61. The meaning and structure of the so-called 'mushroom bodies' of the hexapod brain
62. Vision affects mushroom bodies and central complex in Drosophila melanogaster
63. Context generalization in Drosophila visual learning requires the mushroom bodies
64. The role of Drosophila mushroom body signaling in olfactory memory
65. Disruption of neurotransmission in Drosophila mushroom body blocks retrieval but not acquisition of memory
66. Mushroom bodies suppress locomotor activity in Drosophila melanogaster
67. A higher control center of locomotor behavior in the Drosophila brain
68. Temporally structured replay of awake hippocampal ensemble activity during rapid eye movement sleep
69. Rest in Drosophila is a sleep-like state
70. Correlates of sleep and waking in Drosophila melanogaster
71. Germ-line transformation involving DNA from the period locus in Drosophila melanogaster: Overlapping genomic fragments that restore circadian and ultradian rhythmicity to per0 and per- mutants
72. A pdf neuropeptide gene mutation and ablation of PDF neurons each cause severe abnormalities of behavioral circadian rhythms in Drosophila
73. Differential regulation of circadian pacemaker output by separate clock genes in Drosophila
74. The Drosophila dCREB2 gene affects the circadian clock
75. An emergent mechanism of selective visual attention in Drosophila
76. Mushroom bodies, Ca(2+) oscillations, and the memory gene amnesiac
77. A Drosophila CREB/CREM homolog encodes multiple isoforms, including a cyclic AMP-dependent protein kinase-responsive transcriptional activator and antagonist
78. Subdivision of the Drosophila mushroom bodies by enhancer-trap expression patterns
79. Synchronised neural activity in the Drosophila memory centers and its modulation by amnesiac
80. Improved indicators of cell membrane potential that use fluorescence resonance energy transfer
81. A genetically encoded, fluorescent indicator for cyclic AMP in living cells