The critical role of LIGHT, a TNF family member, in T cell development

Journal of Immunology

Volumn 167, Issue 9, 2001, Pages 5099-5105

  Wang, J ^a   Chun, T ^a   Lo, J C ^a   Wu, Q ^a   Wang, Y ^a   Foster, A ^a   Roca, K ^a   Chen, M ^a   Tamada, K ^a   Chen, L ^a   Wang, C R ^a   Fu, Y X ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN LIGHT; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; CELL MATURATION; CELL SELECTION; CONTROLLED STUDY; HERPES VIRUS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE; THYMOCYTE; TRANSGENIC MOUSE;

EID: 0035500289     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.167.9.5099     Document Type: Article

References (28)

1. Selective events in T cell development
2. Positive selection of lymphocytes
3. Negative selection of lymphocytes
4. Selection of the T cell repertoire
5. T-cell selection
6. Positive selection of thymocytes bearing αβ T cell receptors
7. + thymocytes
8. + thymocytes by two distinct mechanisms differing in their requirement for CD28 costimulation: implications for negative selection in the thymus
9. The thymus and negative selection
10. Several different cell surface molecules control negative selection of medullary thymocytes
11. Death receptors: Signaling and modulation
12. TNF receptor-deficient mice reveal striking differences between several models of thymocyte negative selection
13. LIGHT. a new member of the TNF superfamily, and lymphotoxin α are ligands for herpesvirus entry mediator
14. Modulation of T-cell-mediated immunity in tumor and graft-versus-host disease models through the LIGHT co-stimulatory pathway
15. LIGHT, a novel ligand for lymphotoxin β receptor and TR2/HVEM induces apoptosis and suppresses in vivo tumor formation via gene transfer
16. LIGHT, a TNF-like molecule. costimulates T cell proliferation and is required for dendritic cell-mediated allogeneic T cell response
17. The lymphotoxin-β receptor is necessary and sufficient for LIGHT-mediated apoptosis of tumor cells
18. Evidence for a differential avidity model of T cell selection in the thymus
19. The selection of M3-restricted T cells is dependent on M3 expression and presentation of N-formylated peptides in the thymus
20. The requirement of membrane lymphotoxin for the presence of dendritic cells in lymphoid tissues
21. Characterization of lymphotoxin-αβ complexes on the surface of mouse lymphocytes
22. Development and maturation of secondary lymphoid tissues
23. The ligands and receptors of the lymphotoxin system
24. The thymus selects the useful, neglects the useless and destroys the harmful
25. Functional dissection of the lck proximal promoter
26. CD30 overexpression enhances negative selection in the thymus and mediates programmed cell death via a Bcl-2-sensitive pathway
27. Impaired negative selection of T cells in Hodgkin's disease antigen CD30-deficient mice
28. Cutting edge: Thymic selection and autoreactivity are regulated by multiple coreceptors involved in T cell activation