Kainate receptors expressed by a subpopulation of developing nociceptors rapidly switch from high to low Ca2+ permeability

Journal of Neuroscience

Volumn 21, Issue 13, 2001, Pages 4572-4581

  Lee, C Justin ^a   Kong, Haeyoung ^b   Manzini, M Chiara ^a   Albuquerque, Cristóvão ^a   Chao, Moses V ^b   MacDermott, Amy B ^a  

^a Teachers College   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

C fiber; Calcium permeability; Capsaicin; Dorsal root ganglion; IB4; Kainate receptor; LA4; Lamina II; LD2; Nociceptor

Indexed keywords

KAINIC ACID RECEPTOR;

ANIMAL CELL; ARTICLE; BRAIN DEVELOPMENT; CALCIUM TRANSPORT; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPINAL GANGLION;

EID: 0035399669     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.21-13-04572.2001     Document Type: Article

References (46)

1. The primary afferent depolarizing action of kainate in the rat
2. Assessing the extent of RNA editing in the TMII regions of GluR5 and GluR6 kainate receptors during rat brain development
3. Q/R editing of the rat GluR5 and GluR6 kainate receptors in vivo and in vitro: Evidence for independent developmental, pathological and cellular regulation
4. Cloning of a novel glutamate receptor subunit, GluR5: Expression in the nervous system during development
5. Fractional calcium currents through recombinant GluR channels of the NMDA, AMPA and kainate receptor subtypes
6. The capsaicin receptor: A heat-activated ion channel in the pain pathway
7. Impaired nociception and pain sensation in mice lacking the capsaicin receptor
8. Kainate receptors: Subunits, synaptic localization and function
9. Heteromeric kainate receptors formed by the coassembly of GluR5, GluR6, and GluR7
10. Lactoseries carbohydrates specify subsets of dorsal root ganglion neurons projecting to the superficial dorsal horn of rat spinal cord
11. The methylglutamate, SYM 2081, is a potent and highly selective agonist at kainate receptors
12. Sensory receptor properties of isolectin B4-positive (IB4+) and -negative (IB4-) dorsal root ganglion (DRG) neurones in vivo in the rat
13. Prenatal growth of fine-diameter primary afferents into the rat spinal cord: A transganglionic tracer study
14. The postnatal physiological and neurochemical development of peripheral sensory C fibres
15. GAP-43 expression in the developing rat lumbar spinal cord
16. Developmental changes in the laminar termination of A fibre cutaneous sensory afferents in the rat spinal cord dorsal horn
17. 2+ permeability of AMPA receptors in principal neurons and interneurons in rat CNS
18. Activation of ATP P2X receptors elicits glutamate release from sensory neuron synapses
19. 2+-permeable AMPA receptors
20. Immunocytochemical localization of the vanilloid receptor 1 (VR1): Relationship to neuropeptides, the P2X3 purinoceptor and IB4 binding sites
21. The KA-2 subunit of excitatory amino acid receptors shows widespread expression in brain and forms ion channels with distantly related subunits
22. Glutamate receptor channels in rat DRG neurons: Activation by kainate and quisqualate and blockade of desensitization by Con A
23. Development of peripheral hindlimb and central spinal cord innervation by subpopulations of dorsal root ganglion cells in the embryonic rat
24. Postnatal changes in responses of rat dorsal horn cells to afferent stimulation: A fibre-induced sensitization
25. Dual mechanism for presynaptic modulation by axonal metabotropic glutamate receptor at the mouse mossy fibre-CA3 synapse
26. Presynaptic kainate receptors regulate spinal sensory transmission
27. Calcium entry through a subpopulation of AMPA receptors desensitized neighbouring NMDA receptors in rat dorsal horn neurons
28. Activation of kainate receptors on rat sensory neurons evokes action potential firing and may modulate transmitter release
29. Prenatal development of rat primary afferent fibers. II. Central projections
30. Selective modulation of desensitization at AMPA versus kainate receptors by cyclothiazide and concanavalin A
31. Temporal analysis of the upregulation of GluR5 mRNA editing with age: Regional evaluation
32. High- affinity kainate-type ion channels in rat cerebellar granule cells
33. Postnatal maturation of primary afferent terminations in the substantia gelatinosa of the rat spinal cord. An electron microscopic study
34. Kainate receptor subunits expressed in single cultured hippocampal neurons: Molecular and functional variants by RNA editing
35. Generation and analysis of GluR5(Q636R) kainate receptor mutant mice
36. AMPA, KA and NMDA receptors are expressed in the rat DRG neurones
37. Synaptic activation of presynaptic kainate receptors on hippocampal mossy fiber synapses
38. The development and postnatal organization of primary afferent projections to the rat thoracic spinal cord
39. Distinct kainate receptor phenotypes in immature and mature mouse cerebellar granule cells
40. RNA editing in brain controls a determinant of ion flow in glutamate-gated channels
41. Isolectin B(4)-positive and -negative nociceptors are functionally distinct
42. Effect of RNA editing and subunit co-assembly single-channel properties of recombinant kainate receptors
43. The localization of classical transmitters and neuropeptides within neurons in laminae I-III of the mammalian spinal dorsal horn
44. The cloned capsaicin receptor integrates multiple pain-producing stimuli
45. Differential dependence on GluR2 expression of three characteristic features of AMPA receptors
46. (2S,4R)-4-methylglutamic acid (SYM 2081): A selective, high-affinity ligand for kainate receptors