The regulation of biologic products derived from bioengineered plants

Current Opinion in Biotechnology

Volumn 12, Issue 3, 2001, Pages 308-311

  Stein, Kathryn E ^a   Webber, Keith O ^a  

^a CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; BIOLOGICAL PRODUCT; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; VACCINE;

BIOENGINEERING; CONTRACT; COST EFFECTIVENESS ANALYSIS; DRUG MANUFACTURE; DRUG STRUCTURE; GENETIC TRANSFECTION; GOOD MANUFACTURING PRACTICE; HUMAN; INFECTION; NONHUMAN; PLANT; PLANT SEED; PRIORITY JOURNAL; PROPHYLAXIS; REVIEW; RISK; TECHNOLOGY; TOBACCO MOSAIC VIRUS;

ANIMALS; BIOLOGICAL PRODUCTS; BIOTECHNOLOGY; DNA, RECOMBINANT; GENETIC ENGINEERING; GLYCOPROTEINS; HUMANS; LEGISLATION; PLANTS, GENETICALLY MODIFIED; SEEDS; UNITED STATES; UNITED STATES DEPARTMENT OF AGRICULTURE; UNITED STATES FOOD AND DRUG ADMINISTRATION;

EID: 0035369779     PISSN: 09581669     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0958-1669(00)00217-2     Document Type: Review

References (16)

1. Feasibility of antibody production in plants for human therapeutic use
2. Transgenic plants for therapeutic proteins: Linking upstream and downstream strategies
3. Plants for delivery of edible vaccines
4. A review of oral vaccination with transgenic vegetables
5. Plant seed oil-bodies as carriers for foreign proteins
6. Plants as bioreactors for biopharmaceuticals: Regulatory considerations
7. β(1,2)-Xylose and α(1,3)-fucose residues have a strong contribution in IgE binding to plant glycoallergens
8. N-Glycosylation of a mouse IgG expressed in transgenic tobacco plants
9. A murine monoclonal antibody produced in transgenic plants with plant-specific glycans is not immunogenic in mice
10. In vivo trafficking and catabolism of IgG1 antibodies with Fc associated carbohydrates of differing structure
11. Effect of c2-associated carbohydrate structure on Ig effector function: Studies with chimeric mouse-human IgG1 antibodies in glycosylation mutants of Chinese hamster ovary cells
12. Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets
13. Rapid production of specific vaccines for lymphoma by expression of the tumor-derived single-chain Fv epitopes in tobacco plants