Human NADPH-P450 oxidoreductase modulates the level of cytochrome P450 CYP2D6 holoprotein via haem oxygenase-dependent and -independent pathways

Biochemical Journal

Volumn 356, Issue 2, 2001, Pages 613-619

  Ding, S ^a   Yao, D ^a   Deeni, Y Y ^a   Burchell, B ^a   Wolf, C R ^a   Friedberg, T ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Drug metabolism; Oxidative stress; Pharmacokinetics; Regulation of P450; Toxicology

Indexed keywords

CELL CULTURE; DNA; ENZYMES; PROTEINS; SCAVENGING; SODIUM COMPOUNDS;

ISOFORMS;

BIOCHEMISTRY;

APOPROTEIN; ARSENITE SODIUM; CYTOCHROME P450 2D6; CYTOCHROME P450 REDUCTASE; DIMETHYL SULFOXIDE; FERRITIN; HEMIN; SCAVENGER;

ANIMAL CELL; ARTICLE; CHO CELL; CONTROLLED STUDY; ENZYME ACTIVITY; GENETIC TRANSFECTION; HOMEOSTASIS; HUMAN; HUMAN CELL; IMMUNOCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; BASE SEQUENCE; CHO CELLS; CRICETINAE; CYTOCHROME P-450 CYP2D6; DIMETHYL SULFOXIDE; DNA PRIMERS; HEME OXYGENASE (DECYCLIZING); HEMIN; HOLOENZYMES; HOMEOSTASIS; HUMANS; NADPH-FERRIHEMOPROTEIN REDUCTASE; RECOMBINANT PROTEINS; TRANSFECTION;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS;

EID: 0035367218     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3560613     Document Type: Article

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