Functional high level expression of cytochrome P450 CYP2D6 using baculoviral expression systems

Archives of Biochemistry and Biophysics

Volumn 328, Issue 1, 1996, Pages 143-150

  Paine, Mark J I ^a   Gilham, David ^a   Roberts, Gordon C K ^b   Wolf, C Roland ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

baculovirus expression; coexpression; CYP2D6; drug metabolism; NADPH cytochrome P450 reductase

Indexed keywords

CYTOCHROME P450; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE FERRIHEMOPROTEIN REDUCTASE;

ANIMAL CELL; ARTICLE; BACULOVIRUS; CELL LYSATE; DRUG METABOLISM; ENZYME STRUCTURE; GENE EXPRESSION; LEPIDOPTERA; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROMOTER REGION; X RAY CRYSTALLOGRAPHY;

ANIMALIA; FELIS CATUS; LEPIDOPTERA; SPODOPTERA FRUGIPERDA; UNIDENTIFIED BACULOVIRUS;

EID: 0029986770     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1006/abbi.1996.0154     Document Type: Article

References (42)

1. Wolf, C. R. (1986) Trends Genet. 2, 209-214.
2. Nebert, D. W., Nelson, D. R., Coon, M. J., Estabrook, R. W., Feyereisen, R., Fuji-Kuriyama, Y., Gonzalez, F. J., Guengerich, F. P., Gunsalus, I. C., Johnson, E. F., Loper, J. C., Sato, R., Waterman, M. R., and Waxman, D. J. (1991) DNA Cell Biol. 10, 1-14.
3. Eichelbaum, M., and Gross, A. S. (1990) Pharmacol. Ther. 46, 377-394.
4. Lennard, M. S. (1990) Pharmacol. Toxicol. 67, 273-283.
5. Ayesh, R., Idle J. R., Ritchie, J. C., Crothers, M. J., and Hetzel, M. R. (1984) Nature 312, 169-170.
6. Gough, A. C., Miles, J. S., Spurr, N. K., Moss, J. E., Gaedigk, A., Eichelbaum, M., and Wolf, C. R. (1990) Nature 347, 773-776.
7. Smith, C. A. D., Gough, A. C., Leigh, P. N., Summers, B. A., Harding, A. E., Maraganore, D. M., Sturman, S. G., Schapira, A. H. V., Williams, A. C., Spurr, N. K., and Wolf, C. R. (1992) Lancet 339, 1375-1377.
8. Islam, S. A., Wolf, C. R., Lennard, M. S., and Sternberg, M. J. E. (1991) Carcinogenesis 12, 2211-2219.
9. Wolff, T., Distlerath, L. M., Worthington, M. T., Groopman, J. D., Hammons, G. J., Kadlubar, F. F., Prough, R. A., Martin, M. V., and Guengerich, F. P. (1985) Cancer Res. 45, 2116-2122.
10. Meyer, U. A., Gut, J., Kronbach, T., Skoda, C., Meier, U. T., Catin, T., and Dayer, P. (1986) Xenobiotica 16, 449-464.
11. Poulos, T. L., Finzel, B. C., Gunsalus, I. C., Wagner, G. C., and Kraut, J. (1985) J. Biol. Chem. 260, 16122-16130.
12. Ravichandran, K G., Boddapalli, S. S., Haseman, C. A., Peterson, J. A., and Deisenhofer, J. (1993) Science 261, 731-736.
13. Barnes, H. J., Arlotto, M. P., and Waterman, M. R. (1991) Proc. Natl. Acad. Sci. USA 88, 5597-5601.
14. Smith, G. C. M., Tew, D. G., and Wolf, C. R. (1994) Proc. Natl. Acad. Sci. USA 91, 8710-8714.
15. O'Reilly, D. R, Miller, L. K., and Luckow V. A. (1992) Baculovirus Expression Vectors: A Laboratory Manual, Freeman, New York.
16. Omura, T., and Sato, R. (1964) J. Biol. Chem. 239, 2370-2378.
17. Vermillion, J., and Coon, M. J. (1978) J. Biol. Chem. 253, 8812-8819.
18. Kronbach, T., Mathys, D., Gut, J., Catin, T., and Meyer, U. A. (1987) Analyt. Biochem. 162, 24-32.
19. Otton, S. V., Crewe, H. K., Lennard, M. S., Tucker, G. T., and Woods, H. F. (1988) J. Pharmacol. Exp. Ther. 247, 242-247.
20. Ellis, S. W., Ching, M. S., Watson, P. F., Henderson, C. J., Simula, A. P., Lennard, M. S., Tucker, G. T., and Woods, H. F. (1992) Biochem. Pharmacol. 44, 617-620.
21. Penman, B. W., Reece, J., Smith, T., Yang, C. S., Gelboin, H. V., Gonzalez, F. J., and Crespi, C. L. (1993) Pharmacogenetics 3, 28-39.
22. Bradford, M. (1976) Anal. Biochem. 72, 248-254.
23. Barbeau , A., Cloutier, T., Roy, M., Plasse, L., Paris, S., and Poirer, J. (1987) Lancet 2, 1213-1216.
24. Poirer, J, Roy., M., Campanella, G., Cloutier, T., and Paris, S. (1987) Lancet 2, 386.
25. Mukhopadhyay, C. K., and Chatterjee, I. B. (1994) J. Biol. Chem. 269, 13390-13397.
26. Hasseman, C. A., Kurumbail, R. G., Boddupalli, S. S., Petersen, J. A., and Deisenhofer, J. (1995) Structure 3, 41-62.
27. Gillam, E. M. J., Guo, Z., Martin, M. V., Jenkins, C. M., and Guengerich, P. F. (1995) Arch. Biochem. Biophys. 319, 540-550.
28. Lee, C. A., Kadwell, S. H., Kost, T. A., and Serabjit-Singh, C. J. (1995) Arch. Biochem. Biophys. 319, 157-167.
29. Tamura, S., Korzekwa, K. R., Kimura, S., Gelboin, H. V., and Gonzalez, F. J. (1992) Arch. Biochem. Biophys. 293, 219-223.
30. Kobayashi, S., Murray, S., Watson, D., Sesardic, D., Davis, D. S., and Boobis, A. R. (1989) Biochem. Pharmacol. 38, 2795-2799.
31. Smith, D. A., and Jones, B. C. (1992) Biochem. Pharmacol. 44, 2089-2098.
32. Barnes, H. J., Jenkins, C. M., and Waterman, M. R. (1994) Arch. Biochem. Biophys. 315, 489-494.
33. Buters, J. T. M., Korezekwa, K. R., Kunze, K. L., Omata, Y., Hardwick, J. P., and Gonzalez, F. J. (1994) Drug Metab. Dispos. 22, 688-692.
34. Modi, S., Paine, M. J. I., Sutcliffe, M. L-Y., Primrose, W. U., Wolf, C. R., and Roberts, G. C. K (1995) submitted for publication.
35. Gut, J., Catin, T., Dayer, P., Kronbach, T., Zanger, U., and Meyer, U. A. (1986) J. Biol. Chem. 261, 11734-11743.
36. Schimada, T., Misono, K. S., and Guengerich, F. P. (1986) J. Biol. Chem. 261, 909-921.
37. Schwab, G. E., Raucy, J. L., and Johnson, E. F. (1988) Mol. Pharmacol. 33, 493-499.
38. Patten, C. J., and Koch, P. (1995) Arch. Biochem. Biophys. 317, 504-513.
39. Asseffa, A., Smith, S. J., Nagata, K., Gillette, J., Gelboin, H. V., and Gonzalez, F. J. (1989) Arch. Biochem. Biophys. 274, 481-490.
40. Kimura, S., Umeno, M., Skoda R. C., Meyer U. A., and Gonzalez, F. J. (1989) Am. J. Hum. Genet. 45, 889-904.
41. Henderson, C., and Wolff, C. R. (1992) in Methods in Molecular Biology, Vol 10: Immunochemical Protocols (Manson, M., Ed.), The Human Press Inc., Totawa, NJ.
42. Cupp-Vickery, J. R., and Poulos, T. L. (1995)Nature Struct. Biol. 2, 144-153.